Chemical Compound Review:
gamma-Carboxyglutamate 3-aminopropane-1,1,3- tricarboxylic acid
Synonyms:
AG-F-83503, AC1Q5ROC, CTK1H0810, FT-0640370, AC1L24FS, ...
- The presence of protein-bound gamma-carboxyglutamic acid in calcium-containing renal calculi. Lian, J.B., Prien, E.L., Glimcher, M.J., Gallop, P.M. J. Clin. Invest. (1977)
- Increase in serum bone gamma-carboxyglutamic acid protein with aging in women. Implications for the mechanism of age-related bone loss. Delmas, P.D., Stenner, D., Wahner, H.W., Mann, K.G., Riggs, B.L. J. Clin. Invest. (1983)
- Serum bone gamma carboxyglutamic acid-containing protein in primary hyperparathyroidism and in malignant hypercalcemia. Comparison with bone histomorphometry. Delmas, P.D., Demiaux, B., Malaval, L., Chapuy, M.C., Edouard, C., Meunier, P.J. J. Clin. Invest. (1986)
- The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors. Pan, L.C., Price, P.A. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Gamma-carboxyglutamate excretion and calcinosis in juvenile dermatomyositis. Lian, J.B., Pachman, L.M., Gundberg, C.M., Partridge, R.E., Maryjowski, M.C. Arthritis Rheum. (1982)
- Vitamin K, prothrombin and gamma-carboxyglutamic acid. Stenflo, J. N. Engl. J. Med. (1977)
- Dietary induced subclinical vitamin K deficiency in normal human subjects. Ferland, G., Sadowski, J.A., O'Brien, M.E. J. Clin. Invest. (1993)
- Estimation of bone turnover evaluated by 47Ca-kinetics. Efficiency of serum bone gamma-carboxyglutamic acid-containing protein, serum alkaline phosphatase, and urinary hydroxyproline excretion. Charles, P., Poser, J.W., Mosekilde, L., Jensen, F.T. J. Clin. Invest. (1985)
- New biochemical marker for bone metabolism. Measurement by radioimmunoassay of bone GLA protein in the plasma of normal subjects and patients with bone disease. Price, P.A., Parthemore, J.G., Deftos, L.J. J. Clin. Invest. (1980)
- Matrix GLA protein is a developmental regulator of chondrocyte mineralization and, when constitutively expressed, blocks endochondral and intramembranous ossification in the limb. Yagami, K., Suh, J.Y., Enomoto-Iwamoto, M., Koyama, E., Abrams, W.R., Shapiro, I.M., Pacifici, M., Iwamoto, M. J. Cell Biol. (1999)
- Sequence of the precursor to rat bone gamma-carboxyglutamic acid protein that accumulates in warfarin-treated osteosarcoma cells. Pan, L.C., Williamson, M.K., Price, P.A. J. Biol. Chem. (1985)
- Retinoic acid and glucocorticoids enhance the effect of 1,25-dihydroxyvitamin D3 on bone gamma-carboxyglutamic acid protein synthesis by rat osteosarcoma cells. Nishimoto, S.K., Salka, C., Nimni, M.E. J. Bone Miner. Res. (1987)
- Dietary phylloquinone depletion and repletion in older women. Booth, S.L., Martini, L., Peterson, J.W., Saltzman, E., Dallal, G.E., Wood, R.J. J. Nutr. (2003)
- Evidence for modulation of osteocalcin containing gamma-carboxyglutamic acid residues synthesis by insulin-like growth factor-I and vitamin K2 in human osteosarcoma cell line MG-63. Kudo, Y., Iwashita, M., Takeda, Y., Muraki, T. Eur. J. Endocrinol. (1998)
- Effects on the urinary level of gamma-carboxyglutamic acid caused by the administration of antibiotics with N-methyl thiotetrazole side chains to patients with infectious diseases. Uehara, S., Honjo, K., Hirayama, A., Goto, K. Chemotherapy. (1989)
- Vitamin K-dependent carboxylase: affinity purification from bovine liver by using a synthetic propeptide containing the gamma-carboxylation recognition site. Hubbard, B.R., Ulrich, M.M., Jacobs, M., Vermeer, C., Walsh, C., Furie, B., Furie, B.C. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins. Kulman, J.D., Harris, J.E., Haldeman, B.A., Davie, E.W. Proc. Natl. Acad. Sci. U.S.A. (1997)
- Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Price, P.A., Otsuka, A.A., Poser, J.W., Kristaponis, J., Raman, N. Proc. Natl. Acad. Sci. U.S.A. (1976)
- Direct identification of the calcium-binding amino acid, gamma-carboxyglutamate, in mineralized tissue. Hauschka, P.V., Lian, J.B., Gallop, P.M. Proc. Natl. Acad. Sci. U.S.A. (1975)
- Molecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylase. Price, P.A., Fraser, J.D., Metz-Virca, G. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Structural basis of membrane binding by Gla domains of vitamin K-dependent proteins. Huang, M., Rigby, A.C., Morelli, X., Grant, M.A., Huang, G., Furie, B., Seaton, B., Furie, B.C. Nat. Struct. Biol. (2003)
- In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells. Rehemtulla, A., Roth, D.A., Wasley, L.C., Kuliopulos, A., Walsh, C.T., Furie, B., Furie, B.C., Kaufman, R.J. Proc. Natl. Acad. Sci. U.S.A. (1993)
- Circulating and binding characteristics of wild-type factor IX and certain Gla domain mutants in vivo. Gui, T., Lin, H.F., Jin, D.Y., Hoffman, M., Straight, D.L., Roberts, H.R., Stafford, D.W. Blood (2002)
- Osteocalcin induces chemotaxis, secretion of matrix proteins, and calcium-mediated intracellular signaling in human osteoclast-like cells. Chenu, C., Colucci, S., Grano, M., Zigrino, P., Barattolo, R., Zambonin, G., Baldini, N., Vergnaud, P., Delmas, P.D., Zallone, A.Z. J. Cell Biol. (1994)
- Comparison of amino acid sequence of bovine coagulation Factor IX (Christmas Factor) with that of other vitamin K-dependent plasma proteins. Katayama, K., Ericsson, L.H., Enfield, D.L., Walsh, K.A., Neurath, H., Davie, E.W., Titani, K. Proc. Natl. Acad. Sci. U.S.A. (1979)
- Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Van Buskirk, J.J., Kirsch, W.M., Kleyer, D.L., Barkley, R.M., Koch, T.H. Proc. Natl. Acad. Sci. U.S.A. (1984)
- Conformational changes in conantokin-G induced upon binding of calcium and magnesium as revealed by NMR structural analysis. Chen, Z., Blandl, T., Prorok, M., Warder, S.E., Li, L., Zhu, Y., Pedersen, L.G., Ni, F., Castellino, F.J. J. Biol. Chem. (1998)
- The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Stearns-Kurosawa, D.J., Kurosawa, S., Mollica, J.S., Ferrell, G.L., Esmon, C.T. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Platelet factor 4 stimulates thrombomodulin protein C-activating cofactor activity. A structure-function analysis. Slungaard, A., Key, N.S. J. Biol. Chem. (1994)
- Cell adhesion to phosphatidylserine mediated by a product of growth arrest-specific gene 6. Nakano, T., Ishimoto, Y., Kishino, J., Umeda, M., Inoue, K., Nagata, K., Ohashi, K., Mizuno, K., Arita, H. J. Biol. Chem. (1997)
- Protein C inhibitor secreted from activated platelets efficiently inhibits activated protein C on phosphatidylethanolamine of platelet membrane and microvesicles. Nishioka, J., Ning, M., Hayashi, T., Suzuki, K. J. Biol. Chem. (1998)
- Binding of anticoagulant vitamin K-dependent protein S to platelet-derived microparticles. Dahlbäck, B., Wiedmer, T., Sims, P.J. Biochemistry (1992)
- Vitamin K-dependent carboxylation of pulmonary surfactant-associated proteins. Rannels, S.R., Gallaher, K.J., Wallin, R., Rannels, D.E. Proc. Natl. Acad. Sci. U.S.A. (1987)
- Protein CVermont: symptomatic type II protein C deficiency associated with two GLA domain mutations. Bovill, E.G., Tomczak, J.A., Grant, B., Bhushan, F., Pillemer, E., Rainville, I.R., Long, G.L. Blood (1992)
- Oral anticoagulant treatment: friend or foe in cardiovascular disease? Schurgers, L.J., Aebert, H., Vermeer, C., Bültmann, B., Janzen, J. Blood (2004)
- Metal binding sites of a gamma-carboxyglutamic acid-rich fragment of bovine prothrombin. Furie, B.C., Blumenstein, M., Furie, B. J. Biol. Chem. (1979)
- Mutagenesis of the gamma-carboxyglutamic acid domain of human factor VII to generate maximum enhancement of the membrane contact site. Harvey, S.B., Stone, M.D., Martinez, M.B., Nelsestuen, G.L. J. Biol. Chem. (2003)