Gene Review:
B3GALT1 - UDP-Gal:betaGlcNAc beta 1,3...
Homo sapiens
Synonyms:
Beta-1,3-GalTase 1, Beta-1,3-galactosyltransferase 1, Beta3Gal-T1, Beta3GalT1, UDP-galactose:beta-N-acetyl-glucosamine-beta-1,3-galactosyltransferase 1, ...
- beta 1,3-Galactosyltransferase beta 3Gal-T5 acts on the GlcNAcbeta 1-->3Galbeta 1-->4GlcNAcbeta 1-->R sugar chains of carcinoembryonic antigen and other N-linked glycoproteins and is down-regulated in colon adenocarcinomas. Salvini, R., Bardoni, A., Valli, M., Trinchera, M. J. Biol. Chem. (2001)
- Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression. Freire, T., Bay, S., von Mensdorff-Pouilly, S., Osinaga, E. Cancer Res. (2005)
- Differences in the regulation of specific glycosylation in the pathogenesis of paroxysmal nocturnal hemoglobinuria and the Tn-syndrome. Thurnher, M., Fehr, J., Berger, E.G. Exp. Hematol. (1994)
- Diagnostic and prognostic value of glycosyltransferase mRNA in glioblastoma multiforme patients. Oblinger, J.L., Pearl, D.K., Boardman, C.L., Saqr, H., Prior, T.W., Scheithauer, B.W., Jenkins, R.B., Burger, P.C., Yates, A.J. Neuropathol. Appl. Neurobiol. (2006)
- Association between expression levels of CA 19-9 and N-acetylglucosamine-beta;1,3-galactosyltransferase 5 gene in human pancreatic cancer tissue. Hayashi, N., Nakamori, S., Okami, J., Nagano, H., Dono, K., Umeshita, K., Sakon, M., Narimatsu, H., Monden, M. Pathobiology (2004)
- Persistent repression of a functional allele can be responsible for galactosyltransferase deficiency in Tn syndrome. Thurnher, M., Rusconi, S., Berger, E.G. J. Clin. Invest. (1993)
- A unique molecular chaperone Cosmc required for activity of the mammalian core 1 beta 3-galactosyltransferase. Ju, T., Cummings, R.D. Proc. Natl. Acad. Sci. U.S.A. (2002)
- A family of human beta3-galactosyltransferases. Characterization of four members of a UDP-galactose:beta-N-acetyl-glucosamine/beta-nacetyl-galactosamine beta-1,3-galactosyltransferase family. Amado, M., Almeida, R., Carneiro, F., Levery, S.B., Holmes, E.H., Nomoto, M., Hollingsworth, M.A., Hassan, H., Schwientek, T., Nielsen, P.A., Bennett, E.P., Clausen, H. J. Biol. Chem. (1998)
- Cloning, expression, and characterization of a novel UDP-galactose:beta-N-acetylglucosamine beta1,3-galactosyltransferase (beta3Gal-T5) responsible for synthesis of type 1 chain in colorectal and pancreatic epithelia and tumor cells derived therefrom. Isshiki, S., Togayachi, A., Kudo, T., Nishihara, S., Watanabe, M., Kubota, T., Kitajima, M., Shiraishi, N., Sasaki, K., Andoh, T., Narimatsu, H. J. Biol. Chem. (1999)
- Mucin synthesis and secretion in relation to spontaneous differentiation of colon cancer cells in vitro. Niv, Y., Byrd, J.C., Ho, S.B., Dahiya, R., Kim, Y.S. Int. J. Cancer (1992)
- Leucocyte beta 1,3 galactosyltransferase activity in IgA nephropathy. Allen, A.C., Topham, P.S., Harper, S.J., Feehally, J. Nephrol. Dial. Transplant. (1997)
- Beta-1,3-galactosyltransferase and alpha-1,2-fucosyltransferase involved in the biosynthesis of type-1-chain carbohydrate antigens in human colon adenocarcinoma cell lines. Valli, M., Gallanti, A., Bozzaro, S., Trinchera, M. Eur. J. Biochem. (1998)
- Pathogenesis of IgA nephropathy. Feehally, J., Allen, A.C. Annales de médecine interne. (1999)
- Differential expression of beta1,3galactosyltransferases in human colon cells derived from adenocarcinomas or normal mucosa. Bardoni, A., Valli, M., Trinchera, M. FEBS Lett. (1999)
- T cell clones with normal or defective O-galactosylation from a patient with permanent mixed-field polyagglutinability. Thurnher, M., Clausen, H., Fierz, W., Lanzavecchia, A., Berger, E.G. Eur. J. Immunol. (1992)
- Alterations in neuroblastoma ganglioside synthesis by induction of GD1b synthase by retinoic acid. Hettmer, S., McCarter, R., Ladisch, S., Kaucic, K. Br. J. Cancer (2004)
- Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans. Ju, T., Zheng, Q., Cummings, R.D. Glycobiology (2006)
- Proteome analysis of human monocytic THP-1 cells primed with oxidized low-density lipoproteins. Kang, J.H., Kim, H.T., Choi, M.S., Lee, W.H., Huh, T.L., Park, Y.B., Moon, B.J., Kwon, O.S. Proteomics (2006)
- Molecular cloning and characterization of a novel UDP-Gal:GalNAc(alpha) peptide beta 1,3-galactosyltransferase (C1Gal-T2), an enzyme synthesizing a core 1 structure of O-glycan. Kudo, T., Iwai, T., Kubota, T., Iwasaki, H., Takayma, Y., Hiruma, T., Inaba, N., Zhang, Y., Gotoh, M., Togayachi, A., Narimatsu, H. J. Biol. Chem. (2002)