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Gpnmb  -  glycoprotein (transmembrane) nmb

Mus musculus

Synonyms: DC-HIL, Dchil, Dendritic cell-associated transmembrane protein, Hgfin, Nmb, ...
 
 
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Disease relevance of Gpnmb

 

High impact information on Gpnmb

 

Biological context of Gpnmb

 

Anatomical context of Gpnmb

 

Associations of Gpnmb with chemical compounds

 

Regulatory relationships of Gpnmb

 

Other interactions of Gpnmb

 

Analytical, diagnostic and therapeutic context of Gpnmb

References

  1. Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma. Anderson, M.G., Libby, R.T., Mao, M., Cosma, I.M., Wilson, L.A., Smith, R.S., John, S.W. BMC Biol. (2006) [Pubmed]
  2. Identification and characterization of the genes encoding human and mouse osteoactivin. Owen, T.A., Smock, S.L., Prakash, S., Pinder, L., Brees, D., Krull, D., Castleberry, T.A., Clancy, Y.C., Marks, S.C., Safadi, F.F., Popoff, S.N. Crit. Rev. Eukaryot. Gene Expr. (2003) [Pubmed]
  3. Cloning and characterization of osteoactivin, a novel cDNA expressed in osteoblasts. Safadi, F.F., Xu, J., Smock, S.L., Rico, M.C., Owen, T.A., Popoff, S.N. J. Cell. Biochem. (2001) [Pubmed]
  4. Interacting loci cause severe iris atrophy and glaucoma in DBA/2J mice. Chang, B., Smith, R.S., Hawes, N.L., Anderson, M.G., Zabaleta, A., Savinova, O., Roderick, T.H., Heckenlively, J.R., Davisson, M.T., John, S.W. Nat. Genet. (1999) [Pubmed]
  5. By altering ocular immune privilege, bone marrow-derived cells pathogenically contribute to DBA/2J pigmentary glaucoma. Mo, J.S., Anderson, M.G., Gregory, M., Smith, R.S., Savinova, O.V., Serreze, D.V., Ksander, B.R., Streilein, J.W., John, S.W. J. Exp. Med. (2003) [Pubmed]
  6. Bone-related genes expressed in advanced malignancies induce invasion and metastasis in a genetically defined human cancer model. Rich, J.N., Shi, Q., Hjelmeland, M., Cummings, T.J., Kuan, C.T., Bigner, D.D., Counter, C.M., Wang, X.F. J. Biol. Chem. (2003) [Pubmed]
  7. Molecular cloning of a dendritic cell-associated transmembrane protein, DC-HIL, that promotes RGD-dependent adhesion of endothelial cells through recognition of heparan sulfate proteoglycans. Shikano, S., Bonkobara, M., Zukas, P.K., Ariizumi, K. J. Biol. Chem. (2001) [Pubmed]
  8. Osteoactivin upregulates expression of MMP-3 and MMP-9 in fibroblasts infiltrated into denervated skeletal muscle in mice. Ogawa, T., Nikawa, T., Furochi, H., Kosyoji, M., Hirasaka, K., Suzue, N., Sairyo, K., Nakano, S., Yamaoka, T., Itakura, M., Kishi, K., Yasui, N. Am. J. Physiol., Cell Physiol. (2005) [Pubmed]
  9. Gpnmb is induced in macrophages by IFN-gamma and lipopolysaccharide and acts as a feedback regulator of proinflammatory responses. Ripoll, V.M., Irvine, K.M., Ravasi, T., Sweet, M.J., Hume, D.A. J. Immunol. (2007) [Pubmed]
 
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