Disease relevance of Periapical Periodontitis

• CONCLUSION: Our findings suggest that SP, mast cells, TNF-alpha-positive cells and E-selectin may modulate the pathogenesis of apical periodontitis and may be responsible for stimulating the formation of granuloma with the resorption of periapical bone [1].
• Ledermix is an effective intracanal medicament for the control of postoperative pain associated with acute apical periodontitis, with a rapid onset of pain reduction [2].
• AIMS: The aim of this study was to determine the occurrence and role of yeasts, enteric gram-negative rods and Enterococcus species in root-filled teeth with chronic apical periodontitis, and the antimicrobial effect of iodine potassium iodide (IKI) irrigation [3].
• STUDY DESIGN: Serial and step serial sections of 256 plastic-embedded root apices with attached apical periodontitis lesions that were prepared for a previous investigation were reviewed for the presence of ciliated epithelium-lined radicular cysts [4].

High impact information on Periapical Periodontitis

• Teeth were categorized by diagnosis as having acute apical periodontitis (AAP, teeth with clinical symptoms but no periapical radiolucency, n=22), chronic apical periodontitis (CAP, teeth with radiolucency but no clinical symptoms, n=15) or exacerbated apical periodontitis (EAP, teeth with symptoms and radiolucency, n=25) [5].
• Releasing cytokines with long-range action, such as interleukin-6 (IL-6) and granulocyte-macrophage colony-stimulating factor (GM-CSF), apical periodontitis may induce changes in remote organs of the host [6].
• Identification of cultivable microorganisms from root canals with apical periodontitis following two-visit endodontic treatment with antibiotics/steroid or calcium hydroxide dressings [7].
• More apical periodontitis was seen when the coronal level of the root filling exceeded the marginal bone level (P < 0.005) [8].
• C-reactive protein and serum amyloid A in a canine model of chronic apical periodontitis [9].

Chemical compound and disease context of Periapical Periodontitis

• Endodontic treatment of teeth with apical periodontitis using calcium hydroxide: a long-term study [10].
• A dog model was used to assess and compare in vivo the efficacy of gutta-percha and AH26 sealer versus Resilon with Epiphany primer and sealer [Resilon "Monoblock" System (RMS)] filled roots in preventing apical periodontitis subsequent to coronal inoculation with oral microorganisms [11].
• Talon cusp causing occlusal trauma and acute apical periodontitis: report of a case [12].
• CONCLUSION: Under the conditions of this study, painful teeth with acute apical periodontitis that had been dressed with Ledermix paste gave rise to less pain than that experienced by patients who had a dressing of calcium hydroxide or no dressing at all [2].
• Presence of cholesterol clefts in apical periodontitis lesions is a common histopathological observation [13].

Biological context of Periapical Periodontitis

• Inflammatory cytokine production and specific antibody responses to lipopolysaccharide from endodontopathic black-pigmented bacteria in patients with multilesional periapical periodontitis [14].
• In addition, in order to demonstrate the effects of prostaglandin on the formation process of apical periodontitis, we examined the effects of indomethacin on bone remodeling during experimental apical periodontitis [15].

Anatomical context of Periapical Periodontitis

• The root canals of 55 single-rooted teeth with apical periodontitis were thoroughly instrumented and irrigated with sodium hypochlorite solution [16].
• We have previously demonstrated that detectable levels of prostaglandin E2 exist in periapical exudates (PE-PGE2) from root canals of periapical periodontitis [17].
• This article reports a case of talon cusp affecting the permanent maxillary left lateral incisor that caused clinical problems related to occlusal trauma and apical periodontitis caused by a premature contact [12].
• OBJECTIVE: The objective of this study was to evaluate the histopathologic response of periapical tissues after root canal treatment of necrotic dog teeth with chronic apical periodontitis by using 2 calcium hydroxide-based root canal dressings and 2 root canal sealers [18].

Gene context of Periapical Periodontitis

• In an attempt to understand further the balance between the types of helper T (Th) cells in human apical periodontitis, we examined the difference in the expression of the chemokine receptor and cytokine in samples obtained from human subjects by means of immunohistochemical methods [19].
• OBJECTIVE: The purpose of this study was to compare both subjective (Periapical Index, PAI) and objective (densitometric) radiographic evaluation of healing after endodontic treatment for apical periodontitis [20].
• We examined the induction of inflammatory cytokines (including interleukin-1, interleukin-6, interleukin-8, and tumor necrosis factor-alpha) by several species of possible causative bacteria in periapical periodontitis [21].
• Clinical study of refractory apical periodontitis treated by apicectomy. Part 1. Root canal morphology of resected apex [22].
• CONCLUSION: The PAI and 2 densitometric estimates (AR/N and AR(S)-N(S)) detected healing of apical periodontitis at 12 weeks after treatment [20].

References