Disease relevance of Papilloma, Inverted

• To determine the role of human papillomavirus in the etiology of these lesions, 15 inverted papillomas, five fungiform papillomas, and two squamous cell carcinomas associated with inverted papilloma were examined for the presence of HPV by in situ hybridization (ISH) and polymerase chain reaction (PCR) [1].
• Prevalence of six types of human papillomavirus in inverted papilloma and papillary transitional cell carcinoma of the bladder: an evaluation by polymerase chain reaction [2].
• Successful treatment with isotretinoin was achieved in 1 dog with ICE, 1 with inverted papillomas, and 1 with epidermal cysts [3].
• CONCLUSION: An inverse relation between HPV and p53 overexpression in sinonasal carcinomas associated with inverted papillomas appears to have been demonstrated [4].
• Cuboidal and squamous metaplasia in inverted papillomas involves downregulation of pRb expression along with increased p16 expression in surface cells [5].

High impact information on Papilloma, Inverted

• In the seven patients who received gadopentetate dimeglumine, all inverted papillomas showed solid inhomogeneous enhancement [6].
• Two of the atypical inverted papilloma cases with prominent nucleoli demonstrated an increase in p53 staining throughout the lesions [7].
• Cytokeratin (CK) 20 staining was negative in all cases of inverted papillomas [7].
• Recurrent inverted papilloma: diagnosis with pharmacokinetic dynamic gadolinium-enhanced MR imaging [8].
• We analyzed formalin-fixed and paraffin-embedded materials from urothelial inverted papillomas using flow-cytometric DNA analysis to investigate the intrinsic nature in terms of the malignant potentials [9].

Chemical compound and disease context of Papilloma, Inverted

• The results suggest that the alteration of cellular glycoprotein structure in inverted papilloma is associated with its biologic characterization [10].
• Estrogen and progesterone receptor expression in inverted papilloma [11].

Biological context of Papilloma, Inverted

• There were no statistically significant differences in MIB-1 activity, p53 protein staining, ploidy, and morphologic features between inverted papillomas in patients with and without a history of urothelial carcinoma [12].
• A review of the literature is presented and particular attention is dedicated to the literature concerning analysis of p53 expression, HPV and Epstein-Barr infection and apoptosis in inverted papilloma [13].
• Flow cytometric analysis of formalin-fixed and paraffin-embedded archival material of the inverted papilloma revealed DNA aneuploidy pattern and relatively high percentage of S phase [14].

Anatomical context of Papilloma, Inverted

• In nonpapillomatous nasal mucosa adjacent to inverted papillomas, CK expression in columnar (respiratory) epithelium exactly matched the findings in inverted papillomas [15].
• RESULTS: In the 2 cases of temporal bone inverted papilloma, p53 expression was 43.75% and 4.92%; p27 expression was higher in temporal bone inverted papilloma (82.45% and 70.53%) than in the sinonasal inverted papilloma group [16].
• An intensely stained thick glycocalyx was associated with prominent surface microvilli seen in the following conditions in humans: some control urothelium, inverted papilloma, well and moderately differentiated transitional cell carcinomas and mucin producing adenocarcinomas [17].

Gene context of Papilloma, Inverted

• Significantly reduced p27Kip1 expression was found in surface cells in dysplastic compared with non-dysplastic inverted papillomas, as well as in the total number of cells in carcinoma in situ compared with dysplastic inverted papillomas (P <.05, respectively) [18].
• Cytokeratin (CK) expression was studied in 22 sinonasal inverted papillomas [15].
• Serum squamous cell carcinoma antigen is a useful biologic marker in patients with inverted papillomas of the sinonasal tract [19].
• Increased expression of matrix metalloproteinase-2 and 9 and human papilloma virus infection are associated with malignant transformation of sinonasal inverted papilloma [20].
• Sixteen of 20 inverted papillomas showed p21(waf1/cip1) expression [21].

Analytical, diagnostic and therapeutic context of Papilloma, Inverted

• Immunohistochemistry of p53 in sinonasal inverted papilloma and associated squamous cell carcinoma [22].

References