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MeSH Review

Glycocalyx

 
 
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Disease relevance of Glycocalyx

 

High impact information on Glycocalyx

 

Chemical compound and disease context of Glycocalyx

 

Biological context of Glycocalyx

 

Anatomical context of Glycocalyx

 

Associations of Glycocalyx with chemical compounds

  • The glycocalyx was absent on organisms fixed without osmium and was partially lost when parasites aggregated in their own secretions before fixation [25].
  • Thus it has become feasible to visualize habitats of two surface enzymes, angiotensin-converting enzyme and carboxypeptidase N. Efforts to visualize surface enzymes required development of means of replicating cell surfaces, a methodology that in turn provided the first en face view of the glycocalyx [26].
  • These results, coupled with those of previous studies of permeability changes induced by sialic acid removal, indicate that control of cellular Ca permeability resides in at least two separate sites at the cellular surface: (1) the glycocalyx and (2) the lipid bilayer [27].
  • Glycocalicin, a major glycoprotein of the platelet glycocalyx, is obtained in soluble forms following platelet homogenization and has been purified to homogeneity [28].
  • Since sialic acids are located terminally on the bronchoalveolar lining cells' glycocalyx and play crucial roles, we focused mainly on the existing lung histochemical and biochemical data of these sugar residues, as well as their evolution throughout lung development [29].
 

Gene context of Glycocalyx

  • These results suggest (1) that the intact distal tubular epithelium of the human kidney does not bind crystals, and (2) that crystal retention in the human kidney may depend on the expression of CD44-, OPN-, and-HA rich cell coats by damaged distal tubular epithelium [30].
  • Cytofluorimetry of disaggregated cervical squames confirmed membranous expression and immunogold labelling of ultrathin cryostat sections localized CEA to the glycocalyx and to within cytoplasmic membrane-bound vesicles of mature squames [31].
  • Mucin glycoproteins are major constituents of the glycocalyx that covers mucosal epithelium [32].
  • As it approaches the maternal surface, the attaching embryo encounters the epithelial glycocalyx, which contains the mucin, MUC1 [33].
  • In the cell coat of the cardiomyocytes of the bare heart tube the fibronectin and laminin are concentrated in patches [34].
 

Analytical, diagnostic and therapeutic context of Glycocalyx

References

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  22. Neovasculature induced by vascular endothelial growth factor is fenestrated. Roberts, W.G., Palade, G.E. Cancer Res. (1997) [Pubmed]
  23. Molecular and mechanical bases of focal lipid accumulation in arterial wall. Chien, S. Prog. Biophys. Mol. Biol. (2003) [Pubmed]
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  31. Membranous expression of carcinoembryonic antigen (CEA) in the normal cervical squamous mucosa. Sanders, D.S., Stocks, S.C., Milne, D.M., Milne, G.A., Hopwood, D., Kerr, M.A. J. Pathol. (1992) [Pubmed]
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