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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Petrous Bone

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Disease relevance of Petrous Bone


High impact information on Petrous Bone

  • Further evaluation revealed a large nasopharyngeal carcinoma invading the left petrous bone [6].
  • Posttreatment isolates from the petrous pyramids also were resistant to AM and CM and produced chloramphenicol acetyltransferase and beta-lactamase activity, but had no plasmid DNA [7].
  • Bivariate comparisons with age revealed a number of temporal trends during the period investigated, most notable of which were coronal rotation of the petrous bones and basicranial retroflexion (flattening) [8].
  • In correlation with the clinical course, the intraoperative findings, intraoperative visualization with sodium fluorescein, high-resolution computed tomography of the paranasal sinuses or the petrous bone, computed tomographic cisternography, magnetic resonance imaging, and radionuclide cisternography, there was no false-positive result [9].
  • METHODS: With this technique, a titanium micromesh, tailored according to the defect of the drilled petrous bone and contoured to the outer appearance of the posterolateral cranial base, is used to cover the petrosectomy area [10].

Anatomical context of Petrous Bone


Associations of Petrous Bone with chemical compounds

  • MR and CT correlation of cholesterol cysts of the petrous bone [14].
  • T1-weighted MRI before and after gadolinium confirmed the presence of a mixed tumour of the petrous bone with marked uptake of contrast medium [15].
  • The vessels were visualized by a composite method including the selective injection of the internal auditory artery with coloured silicone or India ink; the counterstaining of the labyrinth with osmic acid; the cutting of the petrous bone in 1-mm thick, serial sections that were cleared with methylsalicylate [16].
  • The external bony auditory canal is morphologically defined as concerns the shape and calibre in successive plane parallel histologic sections of the petrous bone [17].
  • Tests performed on isolated petrous bone resulted in the development of a new surgical instrument suitable for stapedotomy using the CO2 laser [18].

Gene context of Petrous Bone

  • Although typically midline in site, intracranial tumors may arise off the midline, and a significant proportion of these arise unilaterally in the petrous bone [19].
  • The subjects were patients with profound bilateral sensorineural hearing loss who had all had high-resolution computed tomography (CT) with contiguous 1-mm-thick images obtained through the petrous bone in axial sections [20].
  • Chordoma of the petrous bone [21].
  • The importance of microfissures in the petrous bone in the causation of otosclerosis and perilymphatic leakage has long been discussed, and the present techniques may advance our understanding of these pathological conditions[22]
  • Navigation data on current position, direction and distance to a target structure were helpful in the transethmoidal-transsphenoidal approach to the clivus, as well as for accessing deep seated structures (C1-C2 junction, petrous bone tip) [23].

Analytical, diagnostic and therapeutic context of Petrous Bone


  1. Optimizing screening for blunt cerebrovascular injuries. Biffl, W.L., Moore, E.E., Offner, P.J., Brega, K.E., Franciose, R.J., Elliott, J.P., Burch, J.M. Am. J. Surg. (1999) [Pubmed]
  2. Giant cholesterol cysts of the petrous apex. Sataloff, R.T., Myers, D.L., Roberts, B.R., Feldman, M.D., Mayer, D.P., Choi, H.Y. Arch. Otolaryngol. Head Neck Surg. (1988) [Pubmed]
  3. Skull base trauma: diagnosis and management. Samii, M., Tatagiba, M. Neurol. Res. (2002) [Pubmed]
  4. Magnetic resonance imaging of the posterior cranial fossa. Valvassori, G.E., Guzman, M. The Annals of otology, rhinology, and laryngology. (1988) [Pubmed]
  5. Computed tomography evaluation of the inner ear as a diagnostic, counselling and management strategy in patients with congenital sensorineural hearing impairment. Cross, N.C., Stephens, S.D., Francis, M., Hourihan, M.D., Reardon, W. Clinical otolaryngology and allied sciences. (1999) [Pubmed]
  6. Carotid sinus syndrome associated with an occult primary nasopharyngeal carcinoma. Tulchinsky, M., Krasnow, S.H. Arch. Intern. Med. (1988) [Pubmed]
  7. Ampicillin-chloramphenicol-resistant Haemophilus influenzae: plasmid-mediated resistance in bacterial meningitis. Overturf, G.D., Cable, D., Ward, J. Pediatr. Res. (1987) [Pubmed]
  8. Brain size and the human cranial base: a prenatal perspective. Jeffery, N., Spoor, F. Am. J. Phys. Anthropol. (2002) [Pubmed]
  9. Predictive values of beta-trace protein (prostaglandin D synthase) by use of laser-nephelometry assay for the identification of cerebrospinal fluid. Bachmann, G., Petereit, H., Djenabi, U., Michel, O. Neurosurgery (2002) [Pubmed]
  10. Anatomic reconstruction of the posterolateral cranial base with titanium micromesh for combined transpetrosal approach: technical note. Zimmerman, M., Seifert, V. Neurosurgery (1997) [Pubmed]
  11. Microsurgical removal of petroclival meningiomas: a report of 33 patients. Bricolo, A.P., Turazzi, S., Talacchi, A., Cristofori, L. Neurosurgery (1992) [Pubmed]
  12. Spontaneous CSF communication to the middle ear and external auditory canal. A case report. Spar, J.A. Acta radiologica (Stockholm, Sweden : 1987) (1994) [Pubmed]
  13. Obliteration of the middle ear and mastoid cleft in subtotal petrosectomy: indications, technique, and results. Coker, N.J., Jenkins, H.A., Fisch, U. The Annals of otology, rhinology, and laryngology. (1986) [Pubmed]
  14. MR and CT correlation of cholesterol cysts of the petrous bone. Griffin, C., DeLaPaz, R., Enzmann, D. AJNR. American journal of neuroradiology. (1987) [Pubmed]
  15. Histiocytosis X of the petrous bone in the adult: MRI. Bonafé, A., Joomye, H., Jaeger, P., Fraysse, B., Manelfe, C. Neuroradiology. (1994) [Pubmed]
  16. The vascular anatomy of the vestibular labyrinth in man. Mazzoni, A. Acta oto-laryngologica. Supplementum. (1990) [Pubmed]
  17. External bony auditory canal and the tympanic bone. Morphologic properties and influences on the tomographic reproduction. Eckerdal, O., Ahlqvist, J. Acta radiologica: diagnosis. (1980) [Pubmed]
  18. Experimental investigations on the suitability of the carbon dioxide laser for stapedotomy. Thoma, J., Mrowinski, D., Kastenbauer, E.R. The Annals of otology, rhinology, and laryngology. (1986) [Pubmed]
  19. CT and MR findings in patients with chordomas of the petrous apex. Brown, R.V., Sage, M.R., Brophy, B.P. AJNR. American journal of neuroradiology. (1990) [Pubmed]
  20. A new classification for cochleovestibular malformations. Sennaroglu, L., Saatci, I. Laryngoscope (2002) [Pubmed]
  21. Chordoma of the petrous bone. Lipper, M.H., Cail, W.S. South. Med. J. (1991) [Pubmed]
  22. Demonstration of intravital microfissures in undecalcified plastic-embedded temporal bones with the prestaining technique. Frisch, T., Sørensen, M.S., Bretlau, P. The Annals of otology, rhinology, and laryngology. (2001) [Pubmed]
  23. An experimental approach to image guided skull base surgery employing a microscope-based neuronavigation system. Brinker, T., Arango, G., Kaminsky, J., Samii, A., Thorns, U., Vorkapic, P., Samii, M. Acta neurochirurgica. (1998) [Pubmed]
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