Disease relevance of Mohs Surgery

• OBJECTIVE: To present the results of all patients with periocular squamous cell carcinoma (SCC) treated with Mohs' micrographic surgery (MMS) in Australia between 1993 and 1999 [1].
• BACKGROUND: Toluidine blue is a useful stain for detecting basal cell carcinoma during Mohs' micrographic surgery [2].
• Dermatofibrosarcoma protuberans treated with Mohs surgery. A case with CD34 immunostaining variability [3].
• CONCLUSION: Immunoperoxidase-guided Mohs micrographic surgery using low-molecular-weight cytokeratin enhances the sensitivity for detection of mucinous carcinoma, and may help contribute to complete tumor removal [4].
• Re: Questionable utility of Melan-A/Mart-1 immunoperoxidase staining while doing Mohs surgery for melanoma [5].

High impact information on Mohs Surgery

• Surgical Pearl: the use of methylene blue temporary tattoos for tissue orientation in Mohs micrographic surgery [6].
• The formalin-fixed paraffin-embedded tissue technique allows Mohs' surgery to be performed using routine pathology facilities and permits the efficient use of operating room personnel and theatre time [7].
• A retrospective, controlled study was performed of complications of excisional and Mohs micrographic surgery in 653 patients who were being treated with warfarin or platelet inhibitors or with their medications being briefly withheld [8].
• Six lesions were treated by Mohs micrographic surgery, and one case was treated with topical 5% fluorouracil [9].
• Fifty-eight patients participated in a controlled evaluation that compared a transparent film dressing (TFD [Bioclusive]) with a combination of conventional dry gauze dressing (Curity) and antibiotic ointment (Polysporin) in the treatment of fresh skin wounds following Mohs micrographic surgery [10].

Chemical compound and disease context of Mohs Surgery

• Restylane persistent for 23 months found during Mohs micrographic surgery: a source of confusion with hyaluronic acid surrounding basal cell carcinoma [11].
• A deeply invasive squamous cell carcinoma of the right vermilion border of the lip superposed on a nevus flammeus (port-wine stain) was excised by the Mohs micrographic surgery, fixed-tissue technique [12].
• In micrographic (Mohs') surgery, routine haematoxylin and eosin stains may present difficulties in interpretation of infiltrative (morphoeic) basal cell carcinoma [13].

Biological context of Mohs Surgery

• In vivo real-time confocal reflectance microscopy: a noninvasive guide for Mohs micrographic surgery facilitated by aluminum chloride, an excellent contrast enhancer [14].
• Understanding the pre-, peri-, and postoperative considerations in Mohs' surgery will help dermatology nurses better prepare and educate patients who undergo this procedure [15].
• In addition, the anatomy and histology of nail unit SCC, as well as prognostic factors and perioperative evaluation as they relate to performing Mohs micrographic surgery, are reviewed [16].

Anatomical context of Mohs Surgery

• We recommend Mohs micrographic surgery with toluidine blue staining technique for the treatment of adenoid cystic carcinoma [17].

Associations of Mohs Surgery with chemical compounds

• The interaction between propranolol and epinephrine as observed in patients undergoing Mohs' surgery [18].
• Rapid toluidine blue stain for Mohs' micrographic surgery [2].
• Fourteen of these patients had nasal defects and one had a vermilion border defect that resulted from tumor removal by Mohs surgery [19].
• Mohs micrographic surgery using the fresh tissue technique and standard hematoxylin and eosin staining was performed [20].
• OBJECTIVE: The purpose of this study is to compare the efficacy of gentamicin ointment with that of petrolatum for the prevention of suppurative chondritis during second-intention healing of auricular wounds after Mohs surgery [21].

Gene context of Mohs Surgery

• This case demonstrates the variable expression of CD34 antigen by DFSP tumors and emphasizes the need to interpret with caution the results of these immunostains during Mohs surgery [3].
• Adjuvant cytokeratin staining in Mohs micrographic surgery for basal cell carcinoma [22].
• OBJECTIVE: Simple yet effective modifications to Mohs surgery and processing may enhance procedural efficiency, ensure proper tissue orientation and tracking, while greatly reducing "recuts." Using the methods described, Mohs specimens no longer need to be incised or excised with any bevel, thus conserving tissue and facilitating closure [23].
• Rapid skin edge elevation using the OCT compound droplet technique to obtain horizontal microsections in Mohs micrographic surgery [24].
• RESULTS: Neural involvement was detected in H&E preparations before and during excision of the metastatic nodules by Mohs micrographic surgery [25].

Analytical, diagnostic and therapeutic context of Mohs Surgery

• We describe a patient with high-risk cutaneous SCC who is disease-free 1 year after adjuvant radiotherapy subsequent to excision by Mohs micrographic surgery [26].
• Many physicians have overlooked the value of adding zinc chloride tissue fixation prior to Mohs micrographic surgery, partly because of the absence of randomized clinical comparison trials [27].
• Zinc chloride fixative (as described in fixed-tissue Mohs surgery) is useful as a chemical debridement method for osteomyelitic bone [28].
• Current treatments include excisional surgery, Mohs' micrographic surgery, cryotherapy, carbon dioxide laser therapy and topical 5-fluorouracil [29].

References