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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Radiotherapy, Adjuvant

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Disease relevance of Radiotherapy, Adjuvant


High impact information on Radiotherapy, Adjuvant

  • Furthermore, in IB1 patients that did not have indications for adjuvant radiotherapy, 15% of patients with elevated preoperative serum SCC-ag levels recurred within 2 years, compared with 1.6% of patients with normal serum SCC-ag levels (P = .02) [6].
  • CONCLUSION: In early-stage cervical cancer, determination of serum SCC-ag levels allows more refined preoperative estimation of the likelihood for adjuvant radiotherapy than current clinical parameters, and simultaneously identifies patients at high risk for recurrence when treated with surgery only [6].
  • Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region [7].
  • PURPOSE: To assess the factors that predict local control and survival in patients with thymoma treated with adjuvant radiotherapy (RT) and suggest strategies for optimizing adjuvant RT [8].
  • CONCLUSIONS: Our series suggests that the addition of concurrent cisplatin to adjuvant radiotherapy improves the ultimate outcome in patients with resected, locally advanced upper tract urothelial malignancies [9].

Chemical compound and disease context of Radiotherapy, Adjuvant


Biological context of Radiotherapy, Adjuvant


Anatomical context of Radiotherapy, Adjuvant


Associations of Radiotherapy, Adjuvant with chemical compounds


Gene context of Radiotherapy, Adjuvant


Analytical, diagnostic and therapeutic context of Radiotherapy, Adjuvant


  1. Expression of p53, glutathione S-transferase-pi, and Bcl-2 proteins and benefit from adjuvant radiotherapy in breast cancer. Silvestrini, R., Veneroni, S., Benini, E., Daidone, M.G., Luisi, A., Leutner, M., Maucione, A., Kenda, R., Zucali, R., Veronesi, U. J. Natl. Cancer Inst. (1997) [Pubmed]
  2. The second British Stomach Cancer Group trial of adjuvant radiotherapy or chemotherapy in resectable gastric cancer: five-year follow-up. Hallissey, M.T., Dunn, J.A., Ward, L.C., Allum, W.H. Lancet (1994) [Pubmed]
  3. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region. Evans, D.B., Wolff, R.A., Hess, K.R. Ann. Surg. (2000) [Pubmed]
  4. Adjuvant radiotherapy following radical prostatectomy is more effective and less toxic than salvage radiotherapy for a rising prostate specific antigen. Anscher, M.S. Int. J. Cancer (2001) [Pubmed]
  5. Isolated limb perfusion with tumor necrosis factor alpha and melphalan for locally advanced soft tissue sarcoma: the value of adjuvant radiotherapy. Thijssens, K.M., van Ginkel, R.J., Pras, E., Suurmeijer, A.J., Hoekstra, H.J. Ann. Surg. Oncol. (2006) [Pubmed]
  6. Preoperative serum squamous cell carcinoma antigen levels in clinical decision making for patients with early-stage cervical cancer. Reesink-Peters, N., van der Velden, J., Ten Hoor, K.A., Boezen, H.M., de Vries, E.G., Schilthuis, M.S., Mourits, M.J., Nijman, H.W., Aalders, J.G., Hollema, H., Pras, E., Duk, J.M., van der Zee, A.G. J. Clin. Oncol. (2005) [Pubmed]
  7. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region. Hoffman, J.P. Ann. Surg. (2000) [Pubmed]
  8. Radiotherapy and prognostic factors for thymoma: a retrospective study of 175 patients. Zhu, G., He, S., Fu, X., Jiang, G., Liu, T. Int. J. Radiat. Oncol. Biol. Phys. (2004) [Pubmed]
  9. Adjuvant radiotherapy with and without concurrent chemotherapy for locally advanced transitional cell carcinoma of the renal pelvis and ureter. Czito, B., Zietman, A., Kaufman, D., Skowronski, U., Shipley, W. J. Urol. (2004) [Pubmed]
  10. A controlled, prospective, randomised trial of adjuvant chemotherapy or radiotherapy in resectable gastric cancer: interim report. British Stomach Cancer Group. Allum, W.H., Hallissey, M.T., Ward, L.C., Hockey, M.S. Br. J. Cancer (1989) [Pubmed]
  11. Increased survival time in brain glioblastomas by a radioneuroendocrine strategy with radiotherapy plus melatonin compared to radiotherapy alone. Lissoni, P., Meregalli, S., Nosetto, L., Barni, S., Tancini, G., Fossati, V., Maestroni, G. Oncology (1996) [Pubmed]
  12. Computed tomogram prior to prostatectomy. Advantage in defining planning target volumes for postoperative adjuvant radiotherapy in patients with stage C prostate cancer? Höcht, S., Wiegel, T., Bottke, D., Jentsch, H., Sternemann, M., Rosenthal, P., Hinkelbein, W. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (2002) [Pubmed]
  13. Phase II study: adjuvant single-agent carboplatin therapy for clinical stage I seminoma. Krege, S., Kalund, G., Otto, T., Goepel, M., Rübben, H. Eur. Urol. (1997) [Pubmed]
  14. Early occurrence of acute myeloid leukemia following adjuvant radiotherapy and higher cumulative dose of cyclophosphamide in carcinoma breast. Srivastava, A., Murari, M., Datta, N.R. Indian journal of cancer. (2004) [Pubmed]
  15. Different types and different prognosis-study of 310 uterine sarcomas. Nickie-Psikuta, M., Gawrychowski, K. Eur. J. Gynaecol. Oncol. (1993) [Pubmed]
  16. Cutaneous head and neck squamous cell carcinoma metastatic to cervical lymph nodes (nonparotid): a better outcome with surgery and adjuvant radiotherapy. Veness, M.J., Palme, C.E., Smith, M., Cakir, B., Morgan, G.J., Kalnins, I. Laryngoscope (2003) [Pubmed]
  17. Intradural spinal seeding of a clival chordoma. Asano, S., Kawahara, N., Kirino, T. Acta neurochirurgica. (2003) [Pubmed]
  18. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Klinkenbijl, J.H., Jeekel, J., Sahmoud, T., van Pel, R., Couvreur, M.L., Veenhof, C.H., Arnaud, J.P., Gonzalez, D.G., de Wit, L.T., Hennipman, A., Wils, J. Ann. Surg. (1999) [Pubmed]
  19. Primary adenocarcinoma of the seminal vesicles. Thiel, R., Effert, P. J. Urol. (2002) [Pubmed]
  20. Feasibility and efficacy of external beam radiotherapy after hyperthermic isolated limb perfusion with TNF-alpha and melphalan for limb-saving treatment in locally advanced extremity soft-tissue sarcoma. Olieman, A.F., Pras, E., van Ginkel, R.J., Molenaar, W.M., Schraffordt Koops, H., Hoekstra, H.J. Int. J. Radiat. Oncol. Biol. Phys. (1998) [Pubmed]
  21. Raltitrexed (Tomudex) concomitant with radiotherapy as adjuvant treatment for patients with rectal cancer: preliminary results of phase I studies. James, R., Price, P., Valentini, V. Eur. J. Cancer (1999) [Pubmed]
  22. Adjuvant chemotherapy after radical hysterectomy for cervical carcinoma. Lai, C.H., Lin, T.S., Soong, Y.K., Chen, H.F. Gynecol. Oncol. (1989) [Pubmed]
  23. Differences in p53 and PCNA expression in rectal adenocarcinomas due to preoperative adjuvant radiotherapy. Diez, M., Enríquez, J.M., Domínguez, P., Tobaruela, E., Ratia, T., Mugüerza, J.M., Escribano, J., Martín, A., Ruiz, A., Granell, J. Int. J. Biol. Markers (1997) [Pubmed]
  24. The growth factor receptors HER-2/neu and EGFR, their relationship, and their effects on the prognosis in early stage (FIGO I-II) epithelial ovarian carcinoma. Skirnisdóttir, I., Sorbe, B., Seidal, T. Int. J. Gynecol. Cancer (2001) [Pubmed]
  25. HIF1-alpha overexpression indicates a good prognosis in early stage squamous cell carcinomas of the oral floor. Fillies, T., Werkmeister, R., van Diest, P.J., Brandt, B., Joos, U., Buerger, H. BMC Cancer (2005) [Pubmed]
  26. Postoperative borderline elevated CEA predicts for earlier relapse in patients with rectal cancer receiving adjuvant postoperative therapy. Dawson, L.A., Franssen, E., Davey, P. The cancer journal from Scientific American. (1999) [Pubmed]
  27. Surgical management of thyroid cancer invading the airway. McCarty, T.M., Kuhn, J.A., Williams, W.L., Ellenhorn, J.D., O'Brien, J.C., Preskitt, J.T., Lieberman, Z.H., Stephens, J., Odom-Maryon, T., Clarke, K.G., Wagman, L.D. Ann. Surg. Oncol. (1997) [Pubmed]
  28. Secondary leukaemia after cure for locally advanced NSCLC: alkylating type secondary leukaemia after induction therapy with docetaxel and carboplatin for NSCLC IIIB. Griesinger, F., Metz, M., Trümper, L., Schulz, T., Haase, D. Lung Cancer (2004) [Pubmed]
  29. Carcinogenic effects of adjuvant tamoxifen treatment and radiotherapy for early breast cancer. Andersson, M., Storm, H.H., Mouridsen, H.T. Acta oncologica (Stockholm, Sweden) (1992) [Pubmed]
  30. A systematic overview of radiation therapy effects in prostate cancer. Nilsson, S., Norlén, B.J., Widmark, A. Acta oncologica (Stockholm, Sweden) (2004) [Pubmed]
  31. Interferon alpha 2b as maintenance therapy improves outcome in follicular lymphoma. Avilés, A., Neri, N., Huerta-Guzmán, J., Pérez, F., Sotelo, L. Leuk. Lymphoma (2004) [Pubmed]
  32. Pharmacotherapy of gestational trophoblastic disease. Lurain, J.R. Expert opinion on pharmacotherapy. (2003) [Pubmed]
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