The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

Cinnabar     sulfanylidenemercury

Synonyms: Paragite, Almaden, Vermilion, Cinnabarite, Mercurius 6a, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of sulfanylidenemercury

  • The significance of hypertelorism, obliquity of eyes, long palpebral fissures, blue scleras, depressed bridge of nose, and prominent upper vermilion border is discussed [1].
  • Despite substantial increases in total dissolved mercury concentration, methylation rates in cultures of Desulfovibrio desulfuricans ND132 equilibrated with cinnabar did not increase in the presence of polysulfides, as expected due to the large size and charged nature of most of the complexes [2].
  • Prominent physical features of the Aarskog syndrome are short stature, telecanthus, ptosis, short broad nose, long philtrum, thin upper vermilion border and pouty lower lip, low-set jug-handle ears, short broad hands with clawlike positioning of the fingers, broad feet with bulbous toes, ventral scrotal folds, cryptorchidism, and hernias [3].
  • CONCLUSION: Cleft lip mongolian spot appears in high incidence when the cleft goes beyond the vermilion border [4].
  • Results of radiotherapy for squamous cell carcinoma of the vermilion border of the lower lip. A retrospective analysis of 108 patients [5].

Psychiatry related information on sulfanylidenemercury

  • Findings present in at least 50% of reported patients include mental retardation, short stature, pubertal delay, an abnormal nose (usually beaked) with hypoplastic nasal alae, microstomia with narrow maxilla, thin upper lip vermilion, broad hips, small hands, joint limitation, short fingers and toes, and vertebral abnormalities [6].
  • RESULTS: The occlusion, vermilion border of the upper and lower lips separately, and the raters' occupations were all highly significant in influencing attractiveness, social perceptions, and perceived sex of the images (P < .01) [7].

High impact information on sulfanylidenemercury

  • TRPS I patients have sparse scalp hair, a bulbous tip of the nose, a long flat philtrum, a thin upper vermilion border and protruding ears [8].
  • We estimated DNA sequence variation within and between four populations of Drosophila ananassae at Om(1D) and vermilion (v) by using single-strand conformation polymorphism analysis and direct DNA sequencing [9].
  • The cn+ gene functioned as a semidominant transgene and segregated in Mendelian ratios [10].
  • All had severe type I lissencephaly with grossly normal cerebellum and a distinctive facial appearance consisting of prominent forehead, bitemporal hollowing, short nose with upturned nares, protuberant upper lip, thin vermilion border, and small jaw [11].
  • We surveyed sequence variation in four X-linked genes (runt, sevenless, Sex-lethal, and vermilion) that have been used in a parallel study in the closely related species D. melanogaster [12].

Chemical compound and disease context of sulfanylidenemercury


Biological context of sulfanylidenemercury

  • By contrast, mutants expressing a vermilion phenotype only in the F2 (F1 mosaics) all carried single bp changes [14].
  • Molecular genetic variation in the centromeric region of the X chromosome in three Drosophila ananassae populations. I. Contrasts between the vermilion and forked loci [15].
  • It is concluded that an eukaryotic in vivo system with no limitations for the recovery of multi-locus deletions, such as vermilion, should be used for the analysis of DNA damage induced by cross-linking agents [16].
  • Specific locus mutations generated in the vermilion gene by CEA under NER(-) conditions were almost exclusively base pair substitutions (93%) [17].
  • Furthermore, there were high levels of linkage disequilibrium in non-African samples, despite apparently high rates of crossing over in the vermilion region [18].

Anatomical context of sulfanylidenemercury


Associations of sulfanylidenemercury with other chemical compounds


Gene context of sulfanylidenemercury

  • Loricrin, profilaggrin and filaggrin were present in the stratum granulosum of orthokeratinised sites, but expression was abruptly lost at the junction between the vermilion and the intermediate zone [27].
  • Involucrin, which was present at all sites, was restricted to the stratum granulosum in skin, but extended into the stratum spinosum, and gradually into parabasal keratinocytes, across the vermilion and mucosa [27].
  • Males with one of three recessive mutants: White, vermilion, or vestigial, competed with wild type males for females [28].
  • We have estimated DNA sequence variation within and between two populations of Drosophila ananassae, using six-cutter restriction site variation at vermilion (v) and furrowed (fw) [29].
  • The other essential segment lies between the crossveinless and vermilion loci and may contain multiple factors that influence the attachment process [30].

Analytical, diagnostic and therapeutic context of sulfanylidenemercury


  1. More on human immunodeficiency virus embryopathy. Iosub, S., Bamji, M., Stone, R.K., Gromisch, D.S., Wasserman, E. Pediatrics (1987) [Pubmed]
  2. Mercury methylation by Desulfovibrio desulfuricans ND132 in the presence of polysulfides. Jay, J.A., Murray, K.J., Gilmour, C.C., Mason, R.P., Morel, F.M., Roberts, A.L., Hemond, H.F. Appl. Environ. Microbiol. (2002) [Pubmed]
  3. The inheritance of the Aarskog facial-digital-genital syndrome. Berman, P., Desjardins, C., Fraser, F.C. J. Pediatr. (1975) [Pubmed]
  4. Cleft lip mongolian spot: mongolian spot associated with cleft lip. Igawa, H.H., Ohura, T., Sugihara, T., Ishikawa, T., Kumakiri, M. J. Am. Acad. Dermatol. (1994) [Pubmed]
  5. Results of radiotherapy for squamous cell carcinoma of the vermilion border of the lower lip. A retrospective analysis of 108 patients. de Visscher, J.G., Grond, A.J., Botke, G., van der Waal, I. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. (1996) [Pubmed]
  6. Apparent Ruvalcaba syndrome with genitourinary abnormalities. Bialer, M.G., Wilson, W.G., Kelly, T.E. Am. J. Med. Genet. (1989) [Pubmed]
  7. Influence of lips on the perception of malocclusion. Scott, C.R., Goonewardene, M.S., Murray, K. American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics. (2006) [Pubmed]
  8. Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I. Momeni, P., Glöckner, G., Schmidt, O., von Holtum, D., Albrecht, B., Gillessen-Kaesbach, G., Hennekam, R., Meinecke, P., Zabel, B., Rosenthal, A., Horsthemke, B., Lüdecke, H.J. Nat. Genet. (2000) [Pubmed]
  9. A test of the background selection hypothesis based on nucleotide data from Drosophila ananassae. Stephan, W., Xing, L., Kirby, D.A., Braverman, J.M. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  10. Stable transformation of the yellow fever mosquito, Aedes aegypti, with the Hermes element from the housefly. Jasinskiene, N., Coates, C.J., Benedict, M.Q., Cornel, A.J., Rafferty, C.S., James, A.A., Collins, F.H. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  11. Clinical and molecular diagnosis of Miller-Dieker syndrome. Dobyns, W.B., Curry, C.J., Hoyme, H.E., Turlington, L., Ledbetter, D.H. Am. J. Hum. Genet. (1991) [Pubmed]
  12. Contrasted polymorphism patterns in a large sample of populations from the evolutionary genetics model Drosophila simulans. Baudry, E., Derome, N., Huet, M., Veuille, M. Genetics (2006) [Pubmed]
  13. The Anopheles gambiae tryptophan oxygenase gene expressed from a baculovirus promoter complements Drosophila melanogaster vermilion. Besansky, N.J., Mukabayire, O., Benedict, M.Q., Rafferty, C.S., Hamm, D.M., Mcnitt, L. Insect Biochem. Mol. Biol. (1997) [Pubmed]
  14. Mutation spectra of 1,2-dibromoethane, 1,2-dichloroethane and 1-bromo-2-chloroethane in excision repair proficient and repair deficient strains of Drosophila melanogaster. Ballering, L.A., Nivard, M.J., Vogel, E.W. Carcinogenesis (1994) [Pubmed]
  15. Molecular genetic variation in the centromeric region of the X chromosome in three Drosophila ananassae populations. I. Contrasts between the vermilion and forked loci. Stephan, W., Langley, C.H. Genetics (1989) [Pubmed]
  16. The cross-linking agent hexamethylphosphoramide predominantly induces intra-locus and multi-locus deletions in postmeiotic germ cells of Drosophila. Aguirrezabalaga, I., Nivard, M.J., Comendador, M.A., Vogel, E.W. Genetics (1995) [Pubmed]
  17. The in vivo genetic activity profile of the monofunctional nitrogen mustard 2-chloroethylamine differs drastically from its bifunctional counterpart mechlorethamine. Wijen, J.P., Nivard, M.J., Vogel, E.W. Carcinogenesis (2000) [Pubmed]
  18. Molecular variation at the vermilion locus in geographically diverse populations of Drosophila melanogaster and D. simulans. Begun, D.J., Aquadro, C.F. Genetics (1995) [Pubmed]
  19. Molecular analysis of mutations induced in the vermilion gene of Drosophila melanogaster by methyl methanesulfonate. Nivard, M.J., Pastink, A., Vogel, E.W. Genetics (1992) [Pubmed]
  20. Spatial organization of human perioral reflexes. Smith, A., McFarland, D.H., Weber, C.M., Moore, C.A. Exp. Neurol. (1987) [Pubmed]
  21. The use of second-intention healing for partial-thickness Mohs defects involving the vermilion and/or mucosal surfaces of the lip. Gloster, H.M. J. Am. Acad. Dermatol. (2002) [Pubmed]
  22. Functional properties of the surface of the vermilion border of the lips are distinct from those of the facial skin. Kobayashi, H., Tagami, H. Br. J. Dermatol. (2004) [Pubmed]
  23. Oral mucosal lesions in systemic lupus erythematosus--a clinical, histopathological and immunopathological study. Jonsson, R., Heyden, G., Westberg, N.G., Nyberg, G. J. Rheumatol. (1984) [Pubmed]
  24. Sequence analysis of N-ethyl-N-nitrosourea-induced vermilion mutations in Drosophila melanogaster. Pastink, A., Vreeken, C., Nivard, M.J., Searles, L.L., Vogel, E.W. Genetics (1989) [Pubmed]
  25. Analytical imaging studies clarifying the process of the darkening of vermilion in paintings. Keune, K., Boon, J.J. Anal. Chem. (2005) [Pubmed]
  26. Influence of nucleotide excision repair and of dose on the types of vermilion mutations induced by diethyl sulfate in postmeiotic male germ cells of Drosophila. Sierra, L.M., Nivard, M.M., Vogel, E.W. Mutat. Res. (1999) [Pubmed]
  27. The differentiation profile of the epithelium of the human lip. Barrett, A.W., Morgan, M., Nwaeze, G., Kramer, G., Berkovitz, B.K. Arch. Oral Biol. (2005) [Pubmed]
  28. Success of mutant Drosophila at different sex ratios. Just, J., Markow, T. Hereditas (1989) [Pubmed]
  29. Reduced levels of DNA polymorphism and fixed between-population differences in the centromeric region of Drosophila ananassae. Stephan, W., Mitchell, S.J. Genetics (1992) [Pubmed]
  30. Spontaneous formation of compound X chromosomes in Drosophila melanogaster. Morrison, R.J., Raymond, J.D., Zunt, J.R., Lim, J.K., Simmons, M.J. Genetics (1988) [Pubmed]
  31. Separation of plutonium and neptunium species by capillary electrophoresis-inductively coupled plasma-mass spectrometry and application to natural groundwater samples. Kuczewski, B., Marquardt, C.M., Seibert, A., Geckeis, H., Kratz, J.V., Trautmann, N. Anal. Chem. (2003) [Pubmed]
  32. Neurotoxic mechanism of cinnabar and mercuric sulfide on the vestibulo-ocular reflex system of guinea pigs. Young, Y.H., Chuu, J.J., Liu, S.H., Lin-Shiau, S.Y. Toxicol. Sci. (2002) [Pubmed]
  33. Germ line transformation of the yellow fever mosquito, Aedes aegypti, mediated by transpositional insertion of a piggyBac vector. Lobo, N.F., Hua-Van, A., Li, X., Nolen, B.M., Fraser, M.J. Insect Mol. Biol. (2002) [Pubmed]
  34. Mutational spectra induced under distinct excision repair conditions by the 3 methylating agents N-methyl-N-nitrosourea, N-methyl-N'-nitro-N-nitrosoguanidine and N-nitrosodimethylamine in postmeiotic male germ cells of Drosophila. Nivard, M.J., Pastink, A., Vogel, E.W. Mutat. Res. (1996) [Pubmed]
WikiGenes - Universities