Disease relevance of dichloroalumane

• The patients had rates of sweat production greater than 50 mg per minute and had had primary axillary hyperhidrosis that was unresponsive to topical therapy with aluminum chloride for more than one year [1].
• Anhydrous formulation of aluminum chloride for chronic folliculitis [2].
• Concentration of poliovirus from tap water onto membrane filters with aluminum chloride at ambient pH levels [3].
• A method is described for the concentration of an enterovirus from large volumes of tap water by addition of small amounts of aluminum chloride to enhance virus removal by membrane filters [3].
• Ultrastructural alterations of Erwinia carotovora subsp. atroseptica caused by treatment with aluminum chloride and sodium metabisulfite [4].

Psychiatry related information on dichloroalumane

• The present work aims to the investigation of aluminum chloride concentration and reaction time effects on the spectrophotometric behavior of different flavonoids [5].
• OBJECTIVE: To examine the protective effect of Ginkgo biloba leaf extract (GbE) on learning and memory deficit induced by aluminum chloride (AlCl(3)), and explore its mechanisms [6].
• Treatment of Wistar rats with aluminum chloride causes astroglial and neuronal cell damage in the selective brain regions of association cortex and hippocampus, seen in patients with Alzheimer's disease [7].

High impact information on dichloroalumane

• Many neurofibrillary tangles were seen in neurons of spinal cord and cerebrum up to 60 days after injection of aluminum chloride [8].
• Aluminum chloride injected into the brains of developing rabbits produced profound neurofibrillary changes to neurons of spinal cord and cerebrum similar to those produced in adult rabbits, along with a variety of clinical symptoms with the exception of seizures [8].
• Animals examined at 85 and 100 days after injection of aluminum chloride had fewer neurofibrillary tangles of none at all, and apparently they had recovered from the neurofibrillary changes [8].
• Aluminum chloride pretreatment of elastin inhibits elastolysis by matrix metalloproteinases and leads to inhibition of elastin-oriented calcification [9].
• The mechanism by which aluminum chloride stimulates de novo bone formation is unknown [10].

Chemical compound and disease context of dichloroalumane

• In only eight patients (8%) was the compensatory hyperhidrosis considered bothersome, requiring treatment with aluminum chloride in ethanol solution at 25% [11].
• A solution of 30% aluminum chloride was found to be equlvalent to carbol-fuchsin solution in effectively treating symptomatic athlete's foot [12].
• Local topical therapy for hyperhidrosis, such as aluminum chlorohydrate and aluminum chloride, the active ingredients in some antiperspirants, have been tried with some success [13].
• Remission of facial and scalp hyperhidrosis with clonidine hydrochloride and topical aluminum chloride [14].
• The difference in toxicity may be due to the very high content of minerals in the bore hole water, see Table I. c. More fluorine was excreted in faeces when aluminum chloride was added to the diet, as compared to animals which did not receive aluminum chloride [15].

Biological context of dichloroalumane

• Aluminum chloride inhibited the activities of both peaks 1 and 2 with IC50 values of 40-60 microM [16].
• The synthesis of substituted 2-(trifluoromethyl)- and 2-(perfluoroalkyl)-2-hydroxy-2H-chromenes 2a-o was achieved in good yields by intramolecular cyclization of 3-(perfluoroalkyl)-3-phenoxypropenals 1 in the presence of aluminum chloride [17].
• Both types of mutants were characterized by excessive bundling of actin microfilaments and by a strongly increased abundance of actin, a phenotype that could be partially phenocopied in the wild type by treatment with aluminum chloride [18].
• Neonatal Wistar rats were exposed to Al from parturition through adulthood (pre- and post-weaning) by the drinking of 0.3% aluminum chloride (AlCl(3)) solution [19].
• Furthermore, a JNK pathway inhibitor, CEP-11004 (KT8138) inhibited the activation of SAPK/JNK to protect cortical neurons from apoptosis induced by aluminum chloride [20].

Anatomical context of dichloroalumane

• The effects of aluminum chloride on the rate of secretion of the cerebrospinal fluid [21].
• Bacteria exposed to all aluminum chloride concentrations, especially 0.2 M, exhibited loosening of the cell walls, cell wall rupture, cytoplasmic aggregation, and an absence of extracellular vesicles [4].
• Neurofilaments accumulated in perikarya and dendrites of anterior horn cells and Purkinje cells of rabbit treated by aluminum chloride were analysed with a variety of techniques [22].
• In the present study, we demonstrate that exposure of mouse CNS cytoskeletal preparations to aluminum chloride inhibits the degradation of neurofilament proteins by both calcium-dependent and -independent proteases that co-purify with cytoskeletons [23].
• Cholinergic and noradrenergic toxicity of intraventricular aluminum chloride in the rat hippocampus [24].

Associations of dichloroalumane with other chemical compounds

• To investigate the mechanism by which Al reduces Ca absorption, we studied the effect of dietary aluminum chloride (AlCl3) on the relative amounts of intestinal calbindin D-28K in chicks fed diets varying in Ca and phosphorus concentration [25].
• The aging of aluminum hydroxide gel prepared by the reaction of aluminum chloride and ammonium hydroxide was studied by measurement of pH, acid-consuming capacity, hydroxide to aluminum ratio, chloride activity, and X-ray line broadening [26].
• Likewise, the Limulus activity of a test LPS was reduced by the addition of aluminum hydroxide gel or aluminum chloride [27].
• Calcification inhibitor investigations demonstrated that nearly complete inhibition of the calcification of the aortic wall of glutaraldehyde-crosslinked allografts was achieved using a number of individual inhibitors, including controlled release diphosphonates, and pretreatment with either ferric chloride or aluminum chloride [28].
• Each species was exposed to a single soil application of aluminum chloride (0.33 M AlCl(3), pH 2.5), hydrochloric acid (0.39 M HCl, pH 0.6) or water, with or without mycorrhizal inoculation with Pisolithus tinctorius (Coker and Couch) [29].

Gene context of dichloroalumane

• After aluminum chloride administration the most sensitive indicator was an increase of heme oxygenase activity in the liver and a decrease in iron levels in the serum of rats [30].
• On day 21 the uterine horns were used for oxytocin receptor analysis and for in vitro study of myometrial contractile responses to cumulative doses of oxytocin (10(-10) to 10(-6) mol/L) or aluminum fluoride (0.5 to 4.0 mmol/L sodium fluoride in 10 mumol/L aluminum chloride) [31].
• In vitro effect of aluminum chloride on choline acetyltransferase activity of the rat brain during postnatal growth [32].
• Aluminum chloride does not facilitate deposition of human synthetic amyloid beta1-42 peptide in the rat ventricular system of a short-term infusion model [33].
• Dietary aluminum chloride reduces the amount of intestinal calbindin D-28K in chicks fed low calcium or low phosphorus diets [25].

Analytical, diagnostic and therapeutic context of dichloroalumane

• Aluminum chloride induced neurofibrillary changes in the developing rabbit a chronic animal model [8].
• Proximal sciatic axotomy does not inhibit the induction of neurofilamentous inclusions following intracisternal aluminum chloride exposure [34].
• The increased adsorption of viruses in water at pH 7 following addition of aluminum chloride was probably due to flocculation of aluminum, since removal of flocs by filtration greatly reduced the enhancement observed [35].
• The effects of intraperitoneal injections of aluminum chloride were tested on the intestinal calcium absorption and bone calcium mobilization responses to vitamin D3 and 1,25(OH)2D3, as measured by bioassay in chicks [36].
• METHODS: In a double-blind study, cadets attending the US Military Academy were separated into two groups that used either an antiperspirant (20% aluminum chloride hexahydrate in anhydrous ethyl alcohol) or placebo (anhydrous ethyl alcohol) preparation [37].

References