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MeSH Review

Mastectomy, Segmental

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Disease relevance of Mastectomy, Segmental


High impact information on Mastectomy, Segmental


Chemical compound and disease context of Mastectomy, Segmental


Biological context of Mastectomy, Segmental


Anatomical context of Mastectomy, Segmental


Associations of Mastectomy, Segmental with chemical compounds

  • In patients who were assessed as requiring mastectomy at baseline (n = 124), 44% of patients received breast-conserving surgery (BCS) after anastrozole compared with 31% of patients after tamoxifen (P = .23); this difference became significant for patients who were deemed feasible for BCS by their surgeon (46% v 22%, respectively; P = .03) [19].
  • Pathologic specimens from 250 breasts (245 patients) treated between June 1982 and June 1990 with lumpectomy, immediate (boost) interstitial iridium-192 to 15-20 Gy, and external-beam irradiation to the entire breast to 45-50 Gy were reviewed [20].
  • Intraoperative interstitial implantation of iridium 192 during a lumpectomy for carcinoma of the breast has been well tolerated by the patient [21].
  • Thirty patients (15 aged less than 45 years, 15 aged greater than or equal to 45 years; range 28-54 years) underwent mastectomy/lumpectomy with axillary clearance (with or without local irradiation) followed by ovarian irradiation and prednisolone therapy (2.5 mg three times daily for 5 years) [22].
  • Forty cirrhotic patients with Child-Pugh Grade A, aged 40 to 70 yr, scheduled for liver segmentectomy, had anesthesia induced with midazolam 0.1 mg/kg and fentanyl 4 micro g/kg [23].

Gene context of Mastectomy, Segmental


Analytical, diagnostic and therapeutic context of Mastectomy, Segmental


  1. Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer. Fisher, B., Dignam, J., Wolmark, N., DeCillis, A., Emir, B., Wickerham, D.L., Bryant, J., Dimitrov, N.V., Abramson, N., Atkins, J.N., Shibata, H., Deschenes, L., Margolese, R.G. J. Natl. Cancer Inst. (1997) [Pubmed]
  2. Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial. Fisher, B., Dignam, J., Wolmark, N., Wickerham, D.L., Fisher, E.R., Mamounas, E., Smith, R., Begovic, M., Dimitrov, N.V., Margolese, R.G., Kardinal, C.G., Kavanah, M.T., Fehrenbacher, L., Oishi, R.H. Lancet (1999) [Pubmed]
  3. Risk of breast cancer recurrence and contralateral breast cancer in relation to BRCA1 and BRCA2 mutation status following breast-conserving surgery and radiotherapy. Kirova, Y.M., Stoppa-Lyonnet, D., Savignoni, A., Sigal-Zafrani, B., Fabre, N., Fourquet, A. Eur. J. Cancer (2005) [Pubmed]
  4. System for combined three-dimensional morphological and molecular analysis of thick tissue specimens. Fernandez-Gonzalez, R., Jones, A., Garcia-Rodriguez, E., Chen, P.Y., Idica, A., Lockett, S.J., Barcellos-Hoff, M.H., Ortiz-De-Solorzano, C. Microsc. Res. Tech. (2002) [Pubmed]
  5. Sonography-guided percutaneous microwave ablation of high-grade dysplastic nodules in cirrhotic liver. Liang, P., Dong, B., Yu, X., Wang, Y., Sheng, L., Yu, D., Xiao, Q. AJR. American journal of roentgenology. (2005) [Pubmed]
  6. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. Fisher, B., Costantino, J., Redmond, C., Poisson, R., Bowman, D., Couture, J., Dimitrov, N.V., Wolmark, N., Wickerham, D.L., Fisher, E.R. N. Engl. J. Med. (1989) [Pubmed]
  7. Radiation therapy plus tamoxifen versus tamoxifen alone after breast-conserving surgery in postmenopausal women with stage I breast cancer: a decision analysis. Punglia, R.S., Kuntz, K.M., Lee, J.H., Recht, A. J. Clin. Oncol. (2003) [Pubmed]
  8. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. Ellis, M.J., Coop, A., Singh, B., Mauriac, L., Llombert-Cussac, A., Jänicke, F., Miller, W.R., Evans, D.B., Dugan, M., Brady, C., Quebe-Fehling, E., Borgs, M. J. Clin. Oncol. (2001) [Pubmed]
  9. Early-stage breast cancer: local control after conservative surgery and radiation therapy with immediate interstitial boost. Krishnan, L., Jewell, W.R., Mansfield, C.M., Reddy, E.K., Thomas, J.H., Krishnan, E.C. Radiology. (1993) [Pubmed]
  10. Review of the development of letrozole and its use in advanced breast cancer and in the neoadjuvant setting. Bhatnagar, A.S. Breast (Edinburgh, Scotland) (2006) [Pubmed]
  11. Breast-conserving therapy with adjuvant paclitaxel and radiation therapy: feasibility of concurrent treatment. Ellerbroek, N., Martino, S., Mautner, B., Tao, M.L., Rose, C., Botnick, L. The breast journal. (2003) [Pubmed]
  12. Intercostal nerve block for lumpectomy: superior postoperative pain relief with bupivacaine. Atanassoff, P.G., Alon, E., Weiss, B.M. Journal of clinical anesthesia. (1994) [Pubmed]
  13. STK15/Aurora-A expression in primary breast tumors is correlated with nuclear grade but not with prognosis. Royce, M.E., Xia, W., Sahin, A.A., Katayama, H., Johnston, D.A., Hortobagyi, G., Sen, S., Hung, M.C. Cancer (2004) [Pubmed]
  14. Patterns of treatment for ductal carcinoma in situ of the breast in Louisiana, 1988-1999. Wu, X., Chen, V.W., Ruiz, B., Andrews, P.A., Hsieh, M.C., Schmidt, B.A., Correa, C.N., Fontham, E.T. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society. (2003) [Pubmed]
  15. Quality of breast cancer care: what do we know? Malin, J.L., Schuster, M.A., Kahn, K.A., Brook, R.H. J. Clin. Oncol. (2002) [Pubmed]
  16. Control of aromatase activity in breast tumours: the role of the immune system. Singh, A., Purohit, A., Duncan, L.J., Mokbel, K., Ghilchik, M.W., Reed, M.J. J. Steroid Biochem. Mol. Biol. (1997) [Pubmed]
  17. Breast cancer in an intramammary sentinel node. Gajdos, C., Bleiweiss, I.J., Drossman, S., Tartter, P.I. The breast journal. (2001) [Pubmed]
  18. Function-preserving segmentectomy of the cirrhotic liver. Takayama, T., Nakatsuka, T., Shimada, K., Yamamoto, J., Kosuge, T., Yamasaki, S., Hirai, Y., Makuuchi, M. Hepatogastroenterology (1995) [Pubmed]
  19. Neoadjuvant treatment of postmenopausal breast cancer with anastrozole, tamoxifen, or both in combination: the Immediate Preoperative Anastrozole, Tamoxifen, or Combined with Tamoxifen (IMPACT) multicenter double-blind randomized trial. Smith, I.E., Dowsett, M., Ebbs, S.R., Dixon, J.M., Skene, A., Blohmer, J.U., Ashley, S.E., Francis, S., Boeddinghaus, I., Walsh, G. J. Clin. Oncol. (2005) [Pubmed]
  20. Breast cancer with extensive intraductal component: treatment with immediate interstitial boost irradiation. Krishnan, L., Jewell, W.R., Krishnan, E.C., Cherian, R., Lin, F. Radiology. (1992) [Pubmed]
  21. Intraoperative interstitial implantation of iridium 192 in the breast. Mansfield, C.M., Jewell, W.R. Radiology. (1984) [Pubmed]
  22. Meakin adjuvant regimen in premenopausal patients with breast cancer. Smith, D., Dewar, J.A., Horobin, J.M., Scott, J.S., Preece, P.E. The British journal of surgery. (1990) [Pubmed]
  23. A comparison of liver function after hepatectomy in cirrhotic patients between sevoflurane and isoflurane in anesthesia with nitrous oxide and epidural block. Nishiyama, T., Fujimoto, T., Hanaoka, K. Anesth. Analg. (2004) [Pubmed]
  24. Absence of HER4 expression predicts recurrence of ductal carcinoma in situ of the breast. Barnes, N.L., Khavari, S., Boland, G.P., Cramer, A., Knox, W.F., Bundred, N.J. Clin. Cancer Res. (2005) [Pubmed]
  25. Effect of breast surgery on serum levels of insulin-like growth factors (IGF-I, IGF-II, and IGF binding protein-3) in women with benign and malignant breast lesions. Holdaway, I.M., Lethaby, A.E., Mason, B.H., Singh, V., Harman, J.E., MacCormick, M., Civil, I.D. Ann. Surg. Oncol. (2001) [Pubmed]
  26. Predictive value of estrogen receptor status as assessed by ligand-binding assay in patients with early-stage breast cancer treated with breast conserving surgery and radiation therapy. Takei, H., Horiguchi, J., Maemura, M., Koibuchi, Y., Oyama, T., Yokoe, T., Iino, Y., Morishita, Y. Oncol. Rep. (2002) [Pubmed]
  27. Mutant p53 protein overexpression in women with ipsilateral breast tumor recurrence following lumpectomy and radiation therapy. Turner, B.C., Gumbs, A.A., Carbone, C.J., Carter, D., Glazer, P.M., Haffty, B.G. Cancer (2000) [Pubmed]
  28. Sequencing of tamoxifen and radiotherapy after breast-conserving surgery in early-stage breast cancer. Pierce, L.J., Hutchins, L.F., Green, S.R., Lew, D.L., Gralow, J.R., Livingston, R.B., Osborne, C.K., Albain, K.S. J. Clin. Oncol. (2005) [Pubmed]
  29. Undertreatment strongly decreases prognosis of breast cancer in elderly women. Bouchardy, C., Rapiti, E., Fioretta, G., Laissue, P., Neyroud-Caspar, I., Schäfer, P., Kurtz, J., Sappino, A.P., Vlastos, G. J. Clin. Oncol. (2003) [Pubmed]
  30. Electron and high-dose-rate brachytherapy boost in the conservative treatment of stage I-II breast cancer first results of the randomized Budapest boost trial. Polgár, C., Fodor, J., Orosz, Z., Major, T., Takácsi-Nagy, Z., Mangel, L.C., Sulyok, Z., Somogyi, A., Kásler, M., Németh, G. Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]. (2002) [Pubmed]
  31. Tamoxifen with and without radiation after partial mastectomy in patients with involved nodes. Cooke, A.L., Perera, F., Fisher, B., Opeitum, A., Yu, N. Int. J. Radiat. Oncol. Biol. Phys. (1995) [Pubmed]
  32. Extent of resection for hepatocellular carcinoma 2 cm or less in greatest diameter. Yamamoto, M., Takasaki, K., Otsubo, T., Saito, A., Nakano, M. Am. J. Surg. (2002) [Pubmed]
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