Disease relevance of Pyloric Stenosis

• Severe bacterial infections occurred in 85% of the infants, pyloric stenosis in 12%, gastroesophageal reflux in 8%, and thrombotic events in 10% [1].
• Birth defects in relation to Bendectin use in pregnancy. II. Pyloric stenosis [2].
• Because erythromycin is known to cross the placenta and is a recommended treatment for chlamydia and other infections in pregnancy, we explored whether erythromycin taken during pregnancy might similarly lead to an increase in risk of pyloric stenosis [3].
• Reversible edema in a male patient taking parenteral pantoprazole infusion for pyloric stenosis [4].
• A case of Menkes syndrome with pyloric stenosis: an effect of copper deficiency on NOS1 [5]?

High impact information on Pyloric Stenosis

• METHODS: Specimens from 27 infants with pyloric stenosis and 12 controls were processed for immunohistochemistry using a specific antiserum raised against c-kit, a tyrosine kinase receptor expressed by interstitial cells [6].
• Meat-stimulated gastrin release and acid secretion in patients with pyloric stenosis [7].
• This was in contrast with the rise in plasma arginine in patients with pyloric stenosis after surgery, suggesting that the raised level of arginine was due to the presence of the primary tumour [8].
• We report the association of GCT with infantile pyloric stenosis (IPS) [9].
• Plasma chloride and alkalaemia in pyloric stenosis [10].

Chemical compound and disease context of Pyloric Stenosis

• Pyloric stenosis and maternal Bendectin exposure [11].
• As no side-effects are evident following the administration of metoclopramide and no harm is done by delaying surgery for three days, it is suggested that this therapeutic trial should be undertaken in every case of pyloric stenosis or obstruction [12].
• CONCLUSION: The hypothesized association between erythromycin and infantile pyloric stenosis was not seen [13].
• The ulcers became scars after treatment with omeprazole, which cause in severe pyloric stenosis [14].
• Prostaglandin E2 in pyloric stenosis [15].

Anatomical context of Pyloric Stenosis

• The results indicate a reduction of VIP and enkephalin fibers in smooth muscle in pyloric stenosis patients and may be interpreted to support the view that an impaired neuronal function is involved in the pathophysiology of pyloric stenosis [16].
• In 28 infants with pyloric stenosis (IHPS), the presence of intense NSE activity in the ganglia in the pylorus suggested that these neurones were neither immature nor severely degenerated [17].
• We have examined specimens from five patients with pyloric stenosis and from five controls immunocytochemically with respect to the density of nerve fibers containing VIP, substance P, enkephalin, or GRP [16].
• For example, the male excess of "prune belly" or triad syndrome is considered due to the fact that most cases are secondary to obstruction in the penile urethra, and the male excess of pyloric stenosis is hypothesized as being secondary to the muscle hypertrophying effect of testosterone in the male neonate [18].

Gene context of Pyloric Stenosis

• To our knowledge, the association of complete AIS, congenital glaucoma and pyloric stenosis has also never been reported previously [19].
• RESULTS: The most striking difference between tissues from IHPS patients and controls was the marked increase in IGF-I, IGF-IR alpha, IGF-IR beta and PDGF-R in the hypertrophic circular muscle layer, and, to a lesser degree, in the longitudinal muscle in pyloric stenosis [20].
• In pyloric stenosis, c-kit immunoreactivity was absent in the major part of the tissue [6].
• HLA types and ABO blood groups in infants with pyloric stenosis and their mothers [21].
• Immunochemical characterization of neural cell adhesion molecule (NCAM), nitric oxide synthase, and neurofilament protein expression in pyloric muscle of patients with pyloric stenosis [22].

Analytical, diagnostic and therapeutic context of Pyloric Stenosis

• In the past 3 years, three children (ages 2, 4, and 8 years) suffering from peptic pyloric stenosis and repeated vomiting were treated in our department with balloon dilatation followed by H2-receptor antagonist therapy [23].
• However, there are wide plausible ranges for pyloric stenosis risk after erythromycin administration and for the incidence of C trachomatis pneumonia severe enough to require hospitalization; under some combinations of these rates, prophylaxis could be favored [24].
• Twenty patients (14%) required reoperation 5 days to 4 years postoperatively for obstructing lesions (5), wound dehiscence (3), anastomotic leak or dysfunction (6), other atresias (2), choledochal cyst (1), pyloric stenosis (1), and gastroesophageal reflux (2).(ABSTRACT TRUNCATED AT 250 WORDS)[25]
• Fasting serum gastrin levels were measured by radioimmunoassay in 10 patients with pyloric stenosis, before pyloromyotomy and 7 and 15 days after it, and in 11 controls [26].
• This is a case report of an elderly woman who presented with a history of epigastric pain and persistent vomiting diagnosed initially as a duodenal ulcer, later as a pyloric stenosis and at laparotomy was found to have an anterior diaphragmatic hernia with gastric volvulus [27].

References