Gene Review:
NOS1 - nitric oxide synthase 1 (neuronal)
Homo sapiens
Synonyms:
Constitutive NOS, IHPS1, N-NOS, NC-NOS, NOS, ...
Sogos,
Reali,
Fanni,
Curto,
Gremo,
Ciani,
Severi,
Contestabile,
Bartesaghi,
Contestabile,
Roman,
McLain,
Masters,
Hare,
Bloch,
Klotz,
Sedlaczek,
Zumbé,
Engelmann,
Addicks,
Gilchrist,
McCauley,
Befus,
Jarry,
Renaudin,
Denis,
Robard,
Buffin-Meyer,
Karam,
Buzelin,
Paris,
Laboisse,
Vallette,
Khorram,
Garthwaite,
Magness,
Korneev,
Straub,
Kemenes,
Korneeva,
Ott,
Benjamin,
O'Shea,
Leung,
Liu,
Tang,
Ko,
Li,
Lam,
Wong,
Xu,
Liu,
Watanabe,
Song,
Sugimoto,
Horii,
Araki,
Tokumitsu,
Tezuka,
Yamamoto,
Tokuda,
De Sanctis,
MacLean,
Hamada,
Mehta,
Scott,
Jiao,
Yandava,
Kobzik,
Wolyniec,
Fabian,
Venugopal,
Grasemann,
Huang,
Drazen,
Semenza,
- Loss of NOS1 expression in high-grade renal cell carcinoma associated with a shift of NO signalling. Renaudin, K., Denis, M.G., Karam, G., Vallette, G., Buzelin, F., Laboisse, C.L., Jarry, A. Br. J. Cancer (2004)
- Genetic analysis of nitric oxide and endothelin in end-stage renal disease. Freedman, B.I., Yu, H., Anderson, P.J., Roh, B.H., Rich, S.S., Bowden, D.W. Nephrol. Dial. Transplant. (2000)
- NOS1 polymorphism is associated with atopy but not exhaled nitric oxide levels in healthy children. Ali, M., Khoo, S.K., Turner, S., Stick, S., Le Souëf, P., Franklin, P. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology. (2003)
- Expression of two types of nitric oxide synthase mRNA in human neuroblastoma cell lines. Fujisawa, H., Ogura, T., Kurashima, Y., Yokoyama, T., Yamashita, J., Esumi, H. J. Neurochem. (1994)
- Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease. Barreiro, E., Gea, J., Corominas, J.M., Hussain, S.N. Am. J. Respir. Cell Mol. Biol. (2003)
- Evidence for the involvement of endothelial nitric oxide synthase from smooth muscle cells in the erectile function of the human corpus cavernosum. Bloch, W., Klotz, T., Sedlaczek, P., Zumbé, J., Engelmann, U., Addicks, K. Urol. Res. (1998)
- Expression of nitric oxide system in clinically evaluated cases of Alzheimer's disease. Fernández-Vizarra, P., Fernández, A.P., Castro-Blanco, S., Encinas, J.M., Serrano, J., Bentura, M.L., Muñoz, P., Martínez-Murillo, R., Rodrigo, J. Neurobiol. Dis. (2004)
- Timed and targeted differential regulation of nitric oxide synthase (NOS) and anti-NOS genes by reward conditioning leading to long-term memory formation. Korneev, S.A., Straub, V., Kemenes, I., Korneeva, E.I., Ott, S.R., Benjamin, P.R., O'Shea, M. J. Neurosci. (2005)
- Suppression of nitric oxide (NO)-dependent behavior by double-stranded RNA-mediated silencing of a neuronal NO synthase gene. Korneev, S.A., Kemenes, I., Straub, V., Staras, K., Korneeva, E.I., Kemenes, G., Benjamin, P.R., O'Shea, M. J. Neurosci. (2002)
- Nitric oxide in health and disease of the respiratory system. Ricciardolo, F.L., Sterk, P.J., Gaston, B., Folkerts, G. Physiol. Rev. (2004)
- A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Arking, D.E., Pfeufer, A., Post, W., Kao, W.H., Newton-Cheh, C., Ikeda, M., West, K., Kashuk, C., Akyol, M., Perz, S., Jalilzadeh, S., Illig, T., Gieger, C., Guo, C.Y., Larson, M.G., Wichmann, H.E., Marbán, E., O'Donnell, C.J., Hirschhorn, J.N., Kääb, S., Spooner, P.M., Meitinger, T., Chakravarti, A. Nat. Genet. (2006)
- Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Brenman, J.E., Chao, D.S., Gee, S.H., McGee, A.W., Craven, S.E., Santillano, D.R., Wu, Z., Huang, F., Xia, H., Peters, M.F., Froehner, S.C., Bredt, D.S. Cell (1996)
- Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma. De Sanctis, G.T., MacLean, J.A., Hamada, K., Mehta, S., Scott, J.A., Jiao, A., Yandava, C.N., Kobzik, L., Wolyniec, W.W., Fabian, A.J., Venugopal, C.S., Grasemann, H., Huang, P.L., Drazen, J.M. J. Exp. Med. (1999)
- New insights into nNOS regulation of vascular homeostasis. Semenza, G.L. J. Clin. Invest. (2005)
- Nitric oxide in traumatic brain injury. Cherian, L., Hlatky, R., Robertson, C.S. Brain Pathol. (2004)
- In vivo gene transfer of nitric oxide synthase enhances vasomotor function in carotid arteries from normal and cholesterol-Fed rabbits. Channon, K.M., Qian, H., Neplioueva, V., Blazing, M.A., Olmez, E., Shetty, G.A., Youngblood, S.A., Pawloski, J., McMahon, T., Stamler, J.S., George, S.E. Circulation (1998)
- Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation. Ciani, E., Severi, S., Contestabile, A., Bartesaghi, R., Contestabile, A. J. Cell. Sci. (2004)
- Nitric oxide in the peripheral nervous system. Lefebvre, R.A. Ann. Med. (1995)
- Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children. Leung, T.F., Liu, E.K., Tang, N.L., Ko, F.W., Li, C.Y., Lam, C.W., Wong, G.W. Clin. Exp. Allergy (2005)
- Variants of NOS1, NOS2, and NOS3 genes in asthmatics. Gao, P.S., Kawada, H., Kasamatsu, T., Mao, X.Q., Roberts, M.H., Miyamoto, Y., Yoshimura, M., Saitoh, Y., Yasue, H., Nakao, K., Adra, C.N., Kun, J.F., Moro-oka, S., Inoko, H., Ho, L.P., Shirakawa, T., Hopkin, J.M. Biochem. Biophys. Res. Commun. (2000)
- Nitric oxide: from a mysterious labile factor to the molecule of the Nobel Prize. Recent progress in nitric oxide research. Xu, W.M., Liu, L.Z. Cell Res. (1998)
- Linkage and association of childhood asthma with the chromosome 12 genes. Shao, C., Suzuki, Y., Kamada, F., Kanno, K., Tamari, M., Hasegawa, K., Aoki, Y., Kure, S., Yang, X., Endo, H., Takayanagi, R., Nakazawa, C., Morikawa, T., Morikawa, M., Miyabayashi, S., Chiba, Y., Karahashi, M., Saito, S., Tamura, G., Shirakawa, T., Matsubara, Y. J. Hum. Genet. (2004)
- Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism. Steppan, J., Ryoo, S., Schuleri, K.H., Gregg, C., Hasan, R.K., White, A.R., Bugaj, L.J., Khan, M., Santhanam, L., Nyhan, D., Shoukas, A.A., Hare, J.M., Berkowitz, D.E. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Expression of NOS1 and soluble guanylyl cyclase by human kidney epithelial cells: morphological evidence for an autocrine/paracrine action of nitric oxide. Jarry, A., Renaudin, K., Denis, M.G., Robard, M., Buffin-Meyer, B., Karam, G., Buzelin, F., Paris, H., Laboisse, C.L., Vallette, G. Kidney Int. (2003)
- Nitric oxide and excitation-contraction coupling. Hare, J.M. J. Mol. Cell. Cardiol. (2003)
- Genomic analysis and expression patterns reveal distinct genes for endothelial and brain nitric oxide synthase. Sessa, W.C., Harrison, J.K., Luthin, D.R., Pollock, J.S., Lynch, K.R. Hypertension (1993)
- Inflammatory infiltrate, microvessel density, nitric oxide synthase expression, vascular endothelial growth factor expression, and proliferative activity in peri-implant soft tissues around titanium and zirconium oxide healing caps. Degidi, M., Artese, L., Scarano, A., Perrotti, V., Gehrke, P., Piattelli, A. J. Periodontol. (2006)
- Arginase and asthma: novel insights into nitric oxide homeostasis and airway hyperresponsiveness. Meurs, H., Maarsingh, H., Zaagsma, J. Trends Pharmacol. Sci. (2003)
- Nitric oxide "at heart": emerging paradigms after a decade. Pelat, M., Massion, P.B., Balligand, J.L. Archives des maladies du coeur et des vaisseaux. (2005)
- Chimeric enzymes of cytochrome P450 oxidoreductase and neuronal nitric-oxide synthase reductase domain reveal structural and functional differences. Roman, L.J., McLain, J., Masters, B.S. J. Biol. Chem. (2003)
- Determination of the enhancing action of HSP90 on neuronal nitric oxide synthase by EPR spectroscopy. Song, Y., Zweier, J.L., Xia, Y. Am. J. Physiol., Cell Physiol. (2001)
- Post-synaptic density-95 promotes calcium/calmodulin-dependent protein kinase II-mediated Ser847 phosphorylation of neuronal nitric oxide synthase. Watanabe, Y., Song, T., Sugimoto, K., Horii, M., Araki, N., Tokumitsu, H., Tezuka, T., Yamamoto, T., Tokuda, M. Biochem. J. (2003)
- Aberrant expression of nNOS in pyramidal neurons in Alzheimer's disease is highly co-localized with p21ras and p16INK4a. Lüth, H.J., Holzer, M., Gertz, H.J., Arendt, T. Brain Res. (2000)
- Thioredoxin-related regulation of NO/NOS activities. Shao, L.E., Tanaka, T., Gribi, R., Yu, J. Ann. N. Y. Acad. Sci. (2002)
- Expression of nitric oxide synthases and effects of L-arginine and L-NMMA on nitric oxide production and fluid transport in collagenous colitis. Perner, A., Andresen, L., Normark, M., Fischer-Hansen, B., Sørensen, S., Eugen-Olsen, J., Rask-Madsen, J. Gut (2001)
- Dystrophin antisense oligonucleotides decrease expression of nNOS in human neurons. Sogos, V., Reali, C., Fanni, V., Curto, M., Gremo, F. Brain Res. Mol. Brain Res. (2003)
- Somatostatin receptors (sst2) regulate cGMP production in rat retina. Mastrodimou, N., Kiagiadaki, F., Hodjarova, M., Karagianni, E., Thermos, K. Regul. Pept. (2006)
- Expression, localization, and regulation of NOS in human mast cell lines: effects on leukotriene production. Gilchrist, M., McCauley, S.D., Befus, A.D. Blood (2004)
- Temporospatial relationship between the expressions of superoxide dismutase and nitric oxide synthase in the developing human brain: immunohistochemical and immunoblotting analyses. Takikawa, M., Kato, S., Esumi, H., Kurashima, Y., Hirano, A., Asayama, K., Nakashima, K., Ohama, E. Acta Neuropathol. (2001)
- The involvement of nitric oxide and prostaglandins in the cholinergic stimulation of hypothalamie-pituitary-adrenal response during crowding stress. Bugajski, A.J., Gadek-Michalska, A., Bugajski, J. J. Physiol. Pharmacol. (2006)
- Endometrial and myometrial expression of nitric oxide synthase isoforms in pre- and postmenopausal women. Khorram, O., Garthwaite, M., Magness, R.R. J. Clin. Endocrinol. Metab. (1999)
- Induction of nitric oxide synthase in the neointima induced by a periarterial collar in rabbits. Arthur, J.F., Yin, Z.L., Young, H.M., Dusting, G.J. Arterioscler. Thromb. Vasc. Biol. (1997)
- Increased expression of nitric oxide synthase in human lung transplants after nitric oxide inhalation. Cardella, J.A., Keshavjee, S.H., Bai, X.H., Yeoh, J.S., Granton, J.T., Meade, M.O., Matte-Martyn, A., Waddell, T.K., Liu, M. Transplantation (2004)