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MeSH Review

Paraparesis, Tropical Spastic

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Analytical, diagnostic and therapeutic context of Paraparesis, Tropical Spastic


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  2. High human T cell lymphotropic virus type 1 (HTLV-1)-specific precursor cytotoxic T lymphocyte frequencies in patients with HTLV-1-associated neurological disease. Elovaara, I., Koenig, S., Brewah, A.Y., Woods, R.M., Lehky, T., Jacobson, S. J. Exp. Med. (1993) [Pubmed]
  3. Detection of human T lymphotrophic virus type I (HTLV-I) proviral DNA and analysis of T cell receptor V beta CDR3 sequences in spinal cord lesions of HTLV-I-associated myelopathy/tropical spastic paraparesis. Hara, H., Morita, M., Iwaki, T., Hatae, T., Itoyama, Y., Kitamoto, T., Akizuki, S., Goto, I., Watanabe, T. J. Exp. Med. (1994) [Pubmed]
  4. Chronic myelopathy associated with human T-lymphotropic virus type I (HTLV-I). Gessain, A., Gout, O. Ann. Intern. Med. (1992) [Pubmed]
  5. Establishment of human T-cell leukemia virus type I T-cell lymphomas in severe combined immunodeficient mice. Feuer, G., Zack, J.A., Harrington, W.J., Valderama, R., Rosenblatt, J.D., Wachsman, W., Baird, S.M., Chen, I.S. Blood (1993) [Pubmed]
  6. Extracellular matrix protein expression in cerebrospinal fluid from patients with tropical spastic paraparesis associated with HTLV-I and Creutzfeldt-Jakob disease. Cartier, L., García, L., Kettlun, A.M., Castañeda, P., Collados, L., Vásquez, F., Giraudon, P., Belin, M.F., Valenzuela, M.A. Scand. J. Clin. Lab. Invest. (2004) [Pubmed]
  7. Increased expression of human T lymphocyte virus type I (HTLV-I) Tax11-19 peptide-human histocompatibility leukocyte antigen A*201 complexes on CD4+ CD25+ T Cells detected by peptide-specific, major histocompatibility complex-restricted antibodies in patients with HTLV-I-associated neurologic disease. Yamano, Y., Cohen, C.J., Takenouchi, N., Yao, K., Tomaru, U., Li, H.C., Reiter, Y., Jacobson, S. J. Exp. Med. (2004) [Pubmed]
  8. Multiple sclerosis (not tropical spastic paraparesis) on Key West, Florida. Román, G.C., Sheremata, W.A. Lancet (1987) [Pubmed]
  9. IL-15 plays a major role in the persistence of Tax-specific CD8 cells in HAM/TSP patients. Azimi, N., Nagai, M., Jacobson, S., Waldmann, T.A. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  10. Human T cell lymphotropic virus type I Tax protein trans-activates interleukin 15 gene transcription through an NF-kappaB site. Azimi, N., Brown, K., Bamford, R.N., Tagaya, Y., Siebenlist, U., Waldmann, T.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  11. Low frequency of CD94/NKG2A+ T lymphocytes in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis, but not in asymptomatic carriers. Saito, M., Braud, V.M., Goon, P., Hanon, E., Taylor, G.P., Saito, A., Eiraku, N., Tanaka, Y., Usuku, K., Weber, J.N., Osame, M., Bangham, C.R. Blood (2003) [Pubmed]
  12. High-dose zidovudine induction in HTLV-I-associated myelopathy: safety and possible efficacy. Sheremata, W.A., Benedict, D., Squilacote, D.C., Sazant, A., DeFreitas, E. Neurology (1993) [Pubmed]
  13. Pentoxifylline down-regulates adhesion molecule expression and inflammatory cytokine production in cultured peripheral blood mononuclear cells from patients with HTLV-I-associated myelopathy. Tsujino, A., Nakamura, T., Nishiura, Y., Shirabe, S., Furuya, T., Goto, H., Kawakami, A., Eguchi, K., Nagataki, S. J. Neuroimmunol. (1997) [Pubmed]
  14. Methylprednisolone therapy in tropical spastic paraparesis. Duncan, J., Rudge, P. J. Neurol. Neurosurg. Psychiatr. (1990) [Pubmed]
  15. Intermittent high-dose vitamin C therapy in patients with HTLV-I associated myelopathy. Kataoka, A., Imai, H., Inayoshi, S., Tsuda, T. J. Neurol. Neurosurg. Psychiatr. (1993) [Pubmed]
  16. Detection of tumor necrosis factor-alpha-positive cells in cerebrospinal fluid of patients with HTLV-I-associated myelopathy. Nakamura, S., Nagano, I., Yoshioka, M., Shimazaki, S., Onodera, J., Kogure, K. J. Neuroimmunol. (1993) [Pubmed]
  17. Phylogenetic subgroups of human T cell lymphotropic virus (HTLV) type I in the tax gene and their association with different risks for HTLV-I-associated myelopathy/tropical spastic paraparesis. Furukawa, Y., Yamashita, M., Usuku, K., Izumo, S., Nakagawa, M., Osame, M. J. Infect. Dis. (2000) [Pubmed]
  18. Relationship between anti-Tax antibody responses and cocultivatable virus in HTLV-I-infected rabbits. Lydy, S.L., Conner, M.E., Marriott, S.J. Virology (1998) [Pubmed]
  19. Transfusion transmission of human T-lymphotropic virus type I (HTLV-I) from an asymptomatic blood donor: conservation of LTR U3, env, and tax nucleotide sequences in a recipient with HTLV-I-associated myelopathy. Gasmi, M., D'Incan, M., Desgranges, C. Transfusion (1997) [Pubmed]
  20. Cell surface phenotype of in vitro proliferating lymphocytes in HTLV-I-associated myelopathy (HAM/TSP). Eiraku, N., Ijichi, S., Yashiki, S., Osame, M., Sonoda, S. J. Neuroimmunol. (1992) [Pubmed]
  21. Hypoxanthine-guanine phosphoribosyltransferase reporter gene mutation for analysis of in vivo clonal amplification in patients with HTLV type 1-associated Myelopathy/Tropical spastic paraparesis. Albertini, R.J., Ardell, S.K., Judice, S.A., Jacobson, S., Allegretta, M. AIDS Res. Hum. Retroviruses (2000) [Pubmed]
  22. Demonstration of human T lymphotropic virus type I (HTLV-I) tax-specific CD8+ lymphocytes directly in peripheral blood of HTLV-I-associated myelopathy/tropical spastic paraparesis patients by intracellular cytokine detection. Kubota, R., Kawanishi, T., Matsubara, H., Manns, A., Jacobson, S. J. Immunol. (1998) [Pubmed]
  23. HTLV-I-associated myelopathy: clinicopathologic correlation with localization of provirus to spinal cord. Bhigjee, A.I., Wiley, C.A., Wachsman, W., Amenomori, T., Pirie, D., Bill, P.L., Windsor, I. Neurology (1991) [Pubmed]
  24. Common human T cell leukemia virus type 1 (HTLV-1) integration sites in cerebrospinal fluid and blood lymphocytes of patients with HTLV-1-associated myelopathy/tropical spastic paraparesis indicate that HTLV-1 crosses the blood-brain barrier via clonal HTLV-1-infected cells. Cavrois, M., Gessain, A., Gout, O., Wain-Hobson, S., Wattel, E. J. Infect. Dis. (2000) [Pubmed]
  25. Expression of the target antigen for cytotoxic T lymphocytes on adult T-cell-leukemia cells. Kannagi, M., Matsushita, S., Harada, S. Int. J. Cancer (1993) [Pubmed]
  26. Interferon-alpha significantly reduces cerebrospinal fluid CD4 cell subsets in HAM/TSP. Feng, J., Misu, T., Fujihara, K., Saito, H., Takahashi, T., Kohnosu, T., Shiga, Y., Takeda, A., Sato, S., Takase, S., Itoyama, Y. J. Neuroimmunol. (2003) [Pubmed]
  27. Human T-cell lymphotropic virus type I-infected cells extravasate through the endothelial barrier by a local angiogenesis-like mechanism. Bazarbachi, A., Abou Merhi, R., Gessain, A., Talhouk, R., El-Khoury, H., Nasr, R., Gout, O., Sulahian, R., Homaidan, F., de Thé, H., Hermine, O., El-Sabban, M.E. Cancer Res. (2004) [Pubmed]
  28. P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway. Chowdhury, I.H., Radonovich, M., Mahieux, R., Pise-Masison, C., Muralidhar, S., Brady, J.N. J. Gen. Virol. (2003) [Pubmed]
  29. How does interleukin 15 contribute to the pathogenesis of HTLV type 1-associated myelopathy/tropical spastic paraparesis? Azimi, N., Mariner, J., Jacobson, S., Waldmann, T.A. AIDS Res. Hum. Retroviruses (2000) [Pubmed]
  30. Expression of adhesion molecules and monocyte chemoattractant protein -1 (MCP-1) in the spinal cord lesions in HTLV-I-associated myelopathy. Umehara, F., Izumo, S., Takeya, M., Takahashi, K., Sato, E., Osame, M. Acta Neuropathol. (1996) [Pubmed]
  31. Gelatinase activity of matrix metalloproteinases in the cerebrospinal fluid of various patient populations. Valenzuela, M.A., Cartier, L., Collados, L., Kettlun, A.M., Araya, F., Concha, C., Flores, L., Wolf, M.E., Mosnaim, A.D. Res. Commun. Mol. Pathol. Pharmacol. (1999) [Pubmed]
  32. In situ hybridization detection of HTLV-I RNA in peripheral blood mononuclear cells of TSP/HAM patients and their spouses. Beilke, M.A., In, D.R., Gravell, M., Hamilton, R.S., Mora, C.A., Leon-Monzon, M., Rodgers-Johnson, P.E., Gajdusek, D.C., Gibbs, C.J., Zaninovic, V. J. Med. Virol. (1991) [Pubmed]
  33. High-level production of alternatively spliced soluble interleukin-6 receptor in serum of patients with adult T-cell leukaemia/HTLV-I-associated myelopathy. Horiuchi, S., Ampofo, W., Koyanagi, Y., Yamashita, A., Waki, M., Matsumoto, A., Yamamoto, M., Yamamoto, N. Immunology (1998) [Pubmed]
  34. MRI contributes to the differentiation between MS and HTLV-I associated myelopathy in British Columbian coastal natives. Howard, A.K., Li, D.K., Oger, J. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. (2003) [Pubmed]
  35. Human T-cell lymphotropic virus type I (HTLV-I) proviral DNA viral load among asymptomatic patients and patients with HTLV-I-associated myelopathy/tropical spastic paraparesis. Montanheiro, P.A., Oliveira, A.C., Posada-Vergara, M.P., Milagres, A.C., Tauil, C., Marchiori, P.E., Duarte, A.J., Casseb, J. Braz. J. Med. Biol. Res. (2005) [Pubmed]
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