Gene Review:
CYP3A7 - cytochrome P450, family 3, subfamily A,...
Homo sapiens
Synonyms:
CP37, CYPIIIA7, Cytochrome P450 3A7, Cytochrome P450-HFLA, P-450(HFL33), ...
- Novel transcriptional regulation of the human CYP3A7 gene by Sp1 and Sp3 through nuclear factor kappa B-like element. Saito, T., Takahashi, Y., Hashimoto, H., Kamataki, T. J. Biol. Chem. (2001)
- Development of bacterial expression system with high yield of CYP3A7, a human fetus-specific form of cytochrome P450. Inoue, E., Takahashi, Y., Imai, Y., Kamataki, T. Biochem. Biophys. Res. Commun. (2000)
- Establishment of transgenic mice carrying human fetus-specific CYP3A7. Li, Y., Yokoi, T., Kitamura, R., Sasaki, M., Gunji, M., Katsuki, M., Kamataki, T. Arch. Biochem. Biophys. (1996)
- Cytotoxicity of chloroacetanilide herbicide alachlor in HepG2 cells independent of CYP3A4 and CYP3A7. Miranda, S.R., Meyer, S.A. Food Chem. Toxicol. (2007)
- Efficient complementary DNA directed expression of human fetal liver cytochrome P450 (CYP3A7) in insect cells using baculovirus. Sakuma, T., Kitamura, R., Yokoi, T., Kamataki, T. Biochem. Mol. Biol. Int. (1995)
- Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. Schuetz, J.D., Kauma, S., Guzelian, P.S. J. Clin. Invest. (1993)
- Steroid hydroxylation by human fetal CYP3A7 and human NADPH-cytochrome P450 reductase coexpressed in insect cells using baculovirus. Ohmori, S., Fujiki, N., Nakasa, H., Nakamura, H., Ishii, I., Itahashi, K., Kitada, M. Res. Commun. Mol. Pathol. Pharmacol. (1998)
- Functional cytochrome P4503A isoforms in human embryonic tissues: expression during organogenesis. Yang, H.Y., Lee, Q.P., Rettie, A.E., Juchau, M.R. Mol. Pharmacol. (1994)
- A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1. Rodriguez-Antona, C., Axelson, M., Otter, C., Rane, A., Ingelman-Sundberg, M. J. Biol. Chem. (2005)
- Catalysis of drug oxidation during embryogenesis in human hepatic tissues using imipramine as a model substrate. Chen, H., Brzezinski, M.R., Fantel, A.G., Juchau, M.R. Drug Metab. Dispos. (1999)
- Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3. Schmiedlin-Ren, P., Thummel, K.E., Fisher, J.M., Paine, M.F., Lown, K.S., Watkins, P.B. Mol. Pharmacol. (1997)
- Cytochrome P450 (CYP) expression in human myeloblastic and lymphoid cell lines. Nagai, F., Hiyoshi, Y., Sugimachi, K., Tamura, H.O. Biol. Pharm. Bull. (2002)
- Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue. Kivistö, K.T., Bookjans, G., Fromm, M.F., Griese, E.U., Münzel, P., Kroemer, H.K. British journal of clinical pharmacology. (1996)
- Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. Lee, A.J., Cai, M.X., Thomas, P.E., Conney, A.H., Zhu, B.T. Endocrinology (2003)
- Catalysis of the 4-hydroxylation of retinoic acids by cyp3a7 in human fetal hepatic tissues. Chen, H., Fantel, A.G., Juchau, M.R. Drug Metab. Dispos. (2000)
- A review of developmental aspects of cytochrome P450. Oesterheld, J.R. Journal of child and adolescent psychopharmacology. (1998)
- CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele. Sim, S.C., Edwards, R.J., Boobis, A.R., Ingelman-Sundberg, M. Pharmacogenet. Genomics (2005)
- Loss of CYP3A7 gene induction by 1,25-dihydroxyvitamin D3 is caused by less binding of VDR to the proximal ER6 in CYP3A7 gene. Hara, H., Yasunami, Y., Adachi, T. Biochem. Biophys. Res. Commun. (2004)
- Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells. Ohmori, S., Nakasa, H., Asanome, K., Kurose, Y., Ishii, I., Hosokawa, M., Kitada, M. Biochim. Biophys. Acta (1998)
- CYP3A gene expression in human gut epithelium. Kolars, J.C., Lown, K.S., Schmiedlin-Ren, P., Ghosh, M., Fang, C., Wrighton, S.A., Merion, R.M., Watkins, P.B. Pharmacogenetics (1994)
- Cytochrome p450 and glutathione s-transferase mRNA expression in human fetal liver hematopoietic stem cells. Shao, J., Stapleton, P.L., Lin, Y.S., Gallagher, E.P. Drug Metab. Dispos. (2007)
- Effect of cell density and epidermal growth factor on the inducible expression of CYP3A and CYP1A genes in human hepatocytes in primary culture. Greuet, J., Pichard, L., Ourlin, J.C., Bonfils, C., Domergue, J., Le Treut, P., Maurel, P. Hepatology (1997)
- Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma. Tsunedomi, R., Iizuka, N., Hamamoto, Y., Uchimura, S., Miyamoto, T., Tamesa, T., Okada, T., Takemoto, N., Takashima, M., Sakamoto, K., Hamada, K., Yamada-Okabe, H., Oka, M. Int. J. Oncol. (2005)
- Cytochrome P450 CYP3A in human renal cell cancer. Murray, G.I., McFadyen, M.C., Mitchell, R.T., Cheung, Y.L., Kerr, A.C., Melvin, W.T. Br. J. Cancer (1999)
- Perinatal expression and inducibility of human CYP3A7 in C57BL/6N transgenic mice. Li, Y., Yokoi, T., Sasaki, M., Hattori, K., Katsuki, M., Kamataki, T. Biochem. Biophys. Res. Commun. (1996)
- The pregnane X receptor binds to response elements in a genomic context-dependent manner, and PXR activator rifampicin selectively alters the binding among target genes. Song, X., Xie, M., Zhang, H., Li, Y., Sachdeva, K., Yan, B. Drug Metab. Dispos. (2004)
- Inhibitory anti-CYP3A4 peptide antibody: mapping of inhibitory epitope and specificity toward other CYP3A isoforms. Wang, R.W., Newton, D.J., Liu, N.Y., Shou, M., Rushmore, T., Lu, A.Y. Drug Metab. Dispos. (1999)