Gene Review:
Cyp1a1 - cytochrome P450, family 1, subfamily a,...
Rattus norvegicus
Synonyms:
AHH, AHRR, CP11, CYP1, CYP1A1, ...
- Natural furocoumarins as inducers and inhibitors of cytochrome P450 1A1 in rat hepatocytes. Baumgart, A., Schmidt, M., Schmitz, H.J., Schrenk, D. Biochem. Pharmacol. (2005)
- Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis. Thirman, M.J., Albrecht, J.H., Krueger, M.A., Erickson, R.R., Cherwitz, D.L., Park, S.S., Gelboin, H.V., Holtzman, J.L. Proc. Natl. Acad. Sci. U.S.A. (1994)
- In vivo up-regulation of aryl hydrocarbon receptor expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in a dioxin-resistant rat model. Franc, M.A., Pohjanvirta, R., Tuomisto, J., Okey, A.B. Biochem. Pharmacol. (2001)
- Cooperation of the inducible nitric oxide synthase and cytochrome P450 1A1 in mediating lung inflammation and mutagenicity induced by diesel exhaust particles. Zhao, H., Barger, M.W., Ma, J.K., Castranova, V., Ma, J.Y. Environ. Health Perspect. (2006)
- Comparative assessment of metabolic enzyme levels in macrophage populations of the F344 rat. Germolec, D.R., Adams, N.H., Luster, M.I. Biochem. Pharmacol. (1995)
- Evidence for the catabolism of polychlorinated biphenyl-induced cytochrome P-448 by microsomal heme oxygenase, and the inhibition of delta-aminolevulinate dehydratase by polychlorinated biphenyls. Maines, M.D. J. Exp. Med. (1976)
- Effects of enteral nutrition and ethanol on cytochrome P450 distribution in small intestine of male rats. Hakkak, R., Ronis, M.J., Badger, T.M. Gastroenterology (1993)
- Evolutionarily divergent electron donor proteins interact with P450MT2 through the same helical domain but different contact points. Anandatheerthavarada, H.K., Amuthan, G., Biswas, G., Robin, M.A., Murali, R., Waterman, M.R., Avadhani, N.G. EMBO J. (2001)
- Targeting of NH2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2. Addya, S., Anandatheerthavarada, H.K., Biswas, G., Bhagwat, S.V., Mullick, J., Avadhani, N.G. J. Cell Biol. (1997)
- Down-regulation of nuclear aryl hydrocarbon receptor DNA-binding and transactivation functions: requirement for a labile or inducible factor. Reick, M., Robertson, R.W., Pasco, D.S., Fagan, J.B. Mol. Cell. Biol. (1994)
- Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells. Backlund, M., Johansson, I., Mkrtchian, S., Ingelman-Sundberg, M. J. Biol. Chem. (1997)
- alpha-Naphthoflavone-induced CYP1A1 gene expression and cytosolic aryl hydrocarbon receptor transformation. Santostefano, M., Merchant, M., Arellano, L., Morrison, V., Denison, M.S., Safe, S. Mol. Pharmacol. (1993)
- Probing the control elements of the CYP1A1 switching module in H4IIE hepatoma cells. Broccardo, C.J., Billings, R.E., Andersen, M.E., Hanneman, W.H. Toxicol. Sci. (2005)
- Comparison of expression of aldehyde dehydrogenase 3 and CYP1A1 in dominant and recessive aryl hydrocarbon hydroxylase-deficient mutant mouse hepatoma cells. Korkalainen, M.K., Törrönen, A.R., Kärenlampi, S.O. Chem. Biol. Interact. (1995)
- Accumulation of mitochondrial P450MT2, NH(2)-terminal truncated cytochrome P4501A1 in rat brain during chronic treatment with beta-naphthoflavone. A role in the metabolism of neuroactive drugs. Boopathi, E., Anandatheerthavarada, H.K., Bhagwat, S.V., Biswas, G., Fang, J.K., Avadhani, N.G. J. Biol. Chem. (2000)
- Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC. Yabusaki, Y., Shimizu, M., Murakami, H., Nakamura, K., Oeda, K., Ohkawa, H. Nucleic Acids Res. (1984)
- Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation. Roman, B.L., Pollenz, R.S., Peterson, R.E. Toxicol. Appl. Pharmacol. (1998)
- Characterization of in vitro metabolites of the aryl hydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole by liquid chromatography-mass spectrometry and NMR. Bergander, L., Wahlström, N., Alsberg, T., Bergman, J., Rannug, A., Rannug, U. Drug Metab. Dispos. (2003)
- Biodegradation of polychlorinated dibenzo-p-dioxins by recombinant yeast expressing rat CYP1A subfamily. Sakaki, T., Shinkyo, R., Takita, T., Ohta, M., Inouye, K. Arch. Biochem. Biophys. (2002)
- Induction of CYP1A1 and ALDH-3 in lymphoid tissues from Fisher 344 rats exposed to 2,3,7,8-tetrachlorodibenzodioxin (TCDD). Germolec, D.R., Henry, E.C., Maronpot, R., Foley, J.F., Adams, N.H., Gasiewicz, T.A., Luster, M.I. Toxicol. Appl. Pharmacol. (1996)
- Reversible stepwise negative regulation of CYP1A1 in cultured rat epidermal cells. Monk, S.A., Denison, M.S., Rice, R.H. Arch. Biochem. Biophys. (2003)
- Indolo[3,2-b]carbazole inhibits gap junctional intercellular communication in rat primary hepatocytes and acts as a potential tumor promoter. Herrmann, S., Seidelin, M., Bisgaard, H.C., Vang, O. Carcinogenesis (2002)
- An aryl hydrocarbon receptor agonist amplifies the mitogenic actions of estradiol in granulosa cells: evidence of involvement of the cognate receptors. Bussmann, U.A., Bussmann, L.E., Barañao, J.L. Biol. Reprod. (2006)
- Selective centrilobular expression of the aryl hydrocarbon receptor in rat liver. Lindros, K.O., Oinonen, T., Johansson, I., Ingelman-Sundberg, M. J. Pharmacol. Exp. Ther. (1997)
- Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants. Yoshinari, K., Okino, N., Sato, T., Sugatani, J., Miwa, M. Drug Metab. Dispos. (2006)
- Regulation of CYP1A1 transcription via the metabolism of the tryptophan-derived 6-formylindolo[3,2-b]carbazole. Wei, Y.D., Bergander, L., Rannug, U., Rannug, A. Arch. Biochem. Biophys. (2000)
- Ligand/receptor binding for 2,3,7,8-TCDD: implications for risk assessment. Portier, C., Tritscher, A., Kohn, M., Sewall, C., Clark, G., Edler, L., Hoel, D., Lucier, G. Fundamental and applied toxicology : official journal of the Society of Toxicology. (1993)
- Involvement of cytochrome b5 in the metabolism of tetrachlorobiphenyls catalyzed by CYP2B1 and CYP1A1. Matsusue, K., Ariyoshi, N., Oguri, K., Koga, N., Yoshimura, H. Chemosphere (1996)
- Regulation of sulfotransferase gene expression by glucocorticoid hormones and xenobiotics in primary rat hepatocyte culture. Runge-Morris, M. Chem. Biol. Interact. (1998)
- Regional distribution and expression modulation of cytochrome P-450 and epoxide hydrolase mRNAs in the rat brain. Schilter, B., Omiecinski, C.J. Mol. Pharmacol. (1993)
- Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis. Bishayee, A., Roy, S., Chatterjee, M. Oncol. Res. (1999)
- Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the expression of cytochrome P450 1A1, the aryl hydrocarbon receptor, and the aryl hydrocarbon receptor nuclear translocator in rat brain and pituitary. Huang, P., Rannug, A., Ahlbom, E., Håkansson, H., Ceccatelli, S. Toxicol. Appl. Pharmacol. (2000)
- The role of protein tyrosine kinases in CYP1A1 induction by omeprazole and thiabendazole in rat hepatocytes. Lemaire, G., Delescluse, C., Pralavorio, M., Ledirac, N., Lesca, P., Rahmani, R. Life Sci. (2004)
- Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats. Yoshizawa, K., Marsh, T., Foley, J.F., Cai, B., Peddada, S., Walker, N.J., Nyska, A. Toxicol. Sci. (2005)
- CYP1 and AhR expression in 7,12-dimethylbenz[a]anthracene-induced mammary carcinoma of rats prenatally exposed to 3,3',4,4',5-pentachlorobiphenyl. Wakui, S., Yokoo, K., Takahashi, H., Muto, T., Suzuki, Y., Kanai, Y., Hano, H., Furusato, M., Endou, H. Toxicology (2005)
- Dose-response relationships for chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a rat tumor promotion model: quantification and immunolocalization of CYP1A1 and CYP1A2 in the liver. Tritscher, A.M., Goldstein, J.A., Portier, C.J., McCoy, Z., Clark, G.C., Lucier, G.W. Cancer Res. (1992)
- Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood. Ronis, M.J., Rowlands, J.C., Hakkak, R., Badger, T.M. J. Nutr. (2001)