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MeSH Review

Human Body

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Disease relevance of Human Body


Psychiatry related information on Human Body


High impact information on Human Body

  • About 50-60% of the dietary cholesterol is absorbed and retained by the normal human body, but less than 1% of the non-cholesterol sterols are retained [11].
  • Unique portions of cloned actin genes were used to monitor levels of respective mRNAs in developmentally staged whole organisms and dissected body parts [12].
  • The ACTA-scanner, a device for computerized axial tomography, permits cross-sectional radiographic study of the entire human body, including the spine [13].
  • Although the mechanisms governing the production of TIMP are unknown, immunologically identical forms of this glycoprotein have been detected in a wide variety of human body fluids and cell and tissue culture media [14].
  • However, to date, only one conventional GnRH receptor subtype (type I GnRH receptor) uniquely lacking a carboxyl-terminal tail has been found in the human body [15].

Chemical compound and disease context of Human Body


Biological context of Human Body


Anatomical context of Human Body


Associations of Human Body with chemical compounds

  • Chemical data showed that the female allocates the received PA quickly to all body parts [31].
  • Electrode tracks through lateral striatum of anesthetized rats (pentobarbital or ketamine) revealed spontaneously discharging neurons but no discharges evoked by somatosensory examination (passive manipulation and cutaneous stimulation of 14 body parts) [32].
  • Glucose is an essential nutrient for the human body [33].
  • Reactive oxygen species, including H2O2, O2*- and OH* are constantly produced in the human body and are involved in the development of cardiovascular diseases [34].
  • In contrast, the succeeding enzymes of this de novo pathway, dihydroorotate dehydrogenase and orotate phosphoribosyltransferase, were present in all body parts of the worm [35].

Gene context of Human Body

  • To study its role in adult patterns, we have generated clones of mutant exd- cells and examined their effect on the different body parts [36].
  • TRAF-3 immunostaining was detected in many types of cells throughout the human body [37].
  • In addition to the lipid-tailed CD59, soluble lipid-free forms of CD59 are present in human body fluids [38].
  • Limited expression data for SIX3 and SIX6 are available in the literature but, to date, there are no reports of the relative levels of expression of these genes throughout the human body and in adult tissues in particular [39].
  • Our data demonstrate a wide distribution of CRLR throughout the human body and suggest CRLR to be involved in the mediation of a variety of actions in addition to vascular control [40].

Analytical, diagnostic and therapeutic context of Human Body


  1. Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage. Shioda, T., Kato, H., Ohnishi, Y., Tashiro, K., Ikegawa, M., Nakayama, E.E., Hu, H., Kato, A., Sakai, Y., Liu, H., Honjo, T., Nomoto, A., Iwamoto, A., Morimoto, C., Nagai, Y. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  2. The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector. Tanaka, F., Abe, M., Akiyoshi, T., Nomura, T., Sugimachi, K., Kishimoto, T., Suzuki, T., Okada, M. Cancer Res. (1997) [Pubmed]
  3. Estimates of the chromium(VI) reducing capacity in human body compartments as a mechanism for attenuating its potential toxicity and carcinogenicity. De Flora, S., Camoirano, A., Bagnasco, M., Bennicelli, C., Corbett, G.E., Kerger, B.D. Carcinogenesis (1997) [Pubmed]
  4. Transcriptional activation of the Staphylococcus aureus putP gene by low-proline-high osmotic conditions and during infection of murine and human tissues. Schwan, W.R., Lehmann, L., McCormick, J. Infect. Immun. (2006) [Pubmed]
  5. Enzyme immunoassay for detection of pneumococcal antigen in cerebrospinal fluid. Yolken, R.H., Davis, D., Winkelstein, J., Russell, H., Sippel, J.E. J. Clin. Microbiol. (1984) [Pubmed]
  6. Effect of some beta-carbolines on phenylethylamine and apomorphine stereotypies in rats. Kari, I., Rapakko, S., Airaksinen, M.M. Pharmacol. Biochem. Behav. (1980) [Pubmed]
  7. Formed visual hallucinations after metrizamide myelography. Bachman, D.M. Am. J. Ophthalmol. (1984) [Pubmed]
  8. Ideomotor apraxia in patients with Alzheimer disease: why do they use their body parts as objects? Kato, M., Meguro, K., Sato, M., Shimada, Y., Yamazaki, H., Saito, H., Yamaguchi, S., Yamadori, A. Neuropsychiatry, neuropsychology, and behavioral neurology. (2001) [Pubmed]
  9. Psychosocial adaptation after liver transplantation with particular reference to recipients aware of their cancer. Filiberti, A., Mencaglia, E., Regalia, E., Gangeri, L., Pulvirenti, A., Tamburini, M., Camisasca, M., Quagliuolo, M., Mazzaferro, V. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. (1996) [Pubmed]
  10. Effect of weak electromagnetic fields on body image perception in patients with multiple sclerosis. Sandyk, R. Int. J. Neurosci. (1996) [Pubmed]
  11. Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption. Lee, M.H., Lu, K., Hazard, S., Yu, H., Shulenin, S., Hidaka, H., Kojima, H., Allikmets, R., Sakuma, N., Pegoraro, R., Srivastava, A.K., Salen, G., Dean, M., Patel, S.B. Nat. Genet. (2001) [Pubmed]
  12. Transcripts of the six Drosophila actin genes accumulate in a stage- and tissue-specific manner. Fyrberg, E.A., Mahaffey, J.W., Bond, B.J., Davidson, N. Cell (1983) [Pubmed]
  13. Computerized axial tomography in syringomyelia. DiChiro, G., Axelbaum, S.P., Schellinger, D., Twigg, H.L., Ledley, R.S. N. Engl. J. Med. (1975) [Pubmed]
  14. Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Docherty, A.J., Lyons, A., Smith, B.J., Wright, E.M., Stephens, P.E., Harris, T.J., Murphy, G., Reynolds, J.J. Nature (1985) [Pubmed]
  15. Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans. Cheng, C.K., Leung, P.C. Endocr. Rev. (2005) [Pubmed]
  16. Prediction of enzyme binding: human thrombin inhibition study by quantum chemical and artificial intelligence methods based on X-ray structures. Mlinsek, G., Novic, M., Hodoscek, M., Solmajer, T. Journal of chemical information and computer sciences. (2001) [Pubmed]
  17. Induction of apoptosis in human blood T cells by 7,8-dihydroneopterin: the difference between healthy controls and patients with systemic lupus erythematosus. Wirleitner, B., Obermoser, G., Böck, G., Neurauter, G., Schennach, H., Sepp, N., Fuchs, D. Clin. Immunol. (2003) [Pubmed]
  18. Heavy metals in normal Japanese tissues. Amounts of 15 heavy metals in 30 subjects. Sumino, K., Hayakawa, K., Shibata, T., Kitamura, S. Arch. Environ. Health (1975) [Pubmed]
  19. HIV-1 gp120 binding to dendritic cell receptors mobilize the virus to the lymph nodes, but the induced IL-4 synthesis by FcepsilonRI+ hematopoietic cells damages the adaptive immunity--a review, hypothesis, and implications. Becker, Y. Virus Genes (2004) [Pubmed]
  20. Chicken embryo propagation of type I avian adenoviruses. Cowen, B.S. Avian Dis. (1988) [Pubmed]
  21. Cdx-2 homeodomain protein expression in human and rat colorectal adenoma and carcinoma. Ee, H.C., Erler, T., Bhathal, P.S., Young, G.P., James, R.J. Am. J. Pathol. (1995) [Pubmed]
  22. Improved analysis of malondialdehyde in human body fluids. Jentzsch, A.M., Bachmann, H., Fürst, P., Biesalski, H.K. Free Radic. Biol. Med. (1996) [Pubmed]
  23. Influence of CYP2C9 and CYP2D6 polymorphisms on the pharmacokinetics of nateglinide in genotyped healthy volunteers. Kirchheiner, J., Meineke, I., Müller, G., Bauer, S., Rohde, W., Meisel, C., Roots, I., Brockmöller, J. Clinical pharmacokinetics. (2004) [Pubmed]
  24. Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine values measured by an ELISA correlated well with measurements by high-performance liquid chromatography with electrochemical detection. Yoshida, R., Ogawa, Y., Kasai, H. Cancer Epidemiol. Biomarkers Prev. (2002) [Pubmed]
  25. Psychophysiological study on fasting therapy. Yamamoto, H., Suzuki, J., Yamauchi, Y. Psychotherapy and psychosomatics. (1979) [Pubmed]
  26. Protein C inhibitor in human body fluids. Seminal plasma is rich in inhibitor antigen deriving from cells throughout the male reproductive system. Laurell, M., Christensson, A., Abrahamsson, P.A., Stenflo, J., Lilja, H. J. Clin. Invest. (1992) [Pubmed]
  27. Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body. Kambe, N., Hiramatsu, H., Shimonaka, M., Fujino, H., Nishikomori, R., Heike, T., Ito, M., Kobayashi, K., Ueyama, Y., Matsuyoshi, N., Miyachi, Y., Nakahata, T. Blood (2004) [Pubmed]
  28. Human myosin-Vc is a novel class V myosin expressed in epithelial cells. Rodriguez, O.C., Cheney, R.E. J. Cell. Sci. (2002) [Pubmed]
  29. The importance of 5-hydroxytryptamine receptors in the gut. Read, N.W., Gwee, K.A. Pharmacol. Ther. (1994) [Pubmed]
  30. Synthesis and processing of apolipoprotein E in human brain cultures. Dekroon, R.M., Armati, P.J. Glia (2001) [Pubmed]
  31. Sexually transmitted chemical defense in a moth (Utetheisa ornatrix). González, A., Rossini, C., Eisner, M., Eisner, T. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
  32. Anesthetics eliminate somatosensory-evoked discharges of neurons in the somatotopically organized sensorimotor striatum of the rat. West, M.O. J. Neurosci. (1998) [Pubmed]
  33. Regulation of glucose production by the liver. Nordlie, R.C., Foster, J.D., Lange, A.J. Annu. Rev. Nutr. (1999) [Pubmed]
  34. Inactivation of SRC family tyrosine kinases by reactive oxygen species in vivo. Tang, H., Hao, Q., Rutherford, S.A., Low, B., Zhao, Z.J. J. Biol. Chem. (2005) [Pubmed]
  35. Contribution of the bacterial endosymbiont to the biosynthesis of pyrimidine nucleotides in the deep-sea tube worm Riftia pachyptila. Minic, Z., Simon, V., Penverne, B., Gaill, F., Hervé, G. J. Biol. Chem. (2001) [Pubmed]
  36. Control of Drosophila adult pattern by extradenticle. González-Crespo, S., Morata, G. Development (1995) [Pubmed]
  37. Immunohistochemical analysis of in vivo patterns of TRAF-3 expression, a member of the TNF receptor-associated factor family. Krajewski, S., Zapata, J.M., Krajewska, M., VanArsdale, T., Shabaik, A., Gascoyne, R.D., Reed, J.C. J. Immunol. (1997) [Pubmed]
  38. Structural composition and functional characterization of soluble CD59: heterogeneity of the oligosaccharide and glycophosphoinositol (GPI) anchor revealed by laser-desorption mass spectrometric analysis. Meri, S., Lehto, T., Sutton, C.W., Tyynelä, J., Baumann, M. Biochem. J. (1996) [Pubmed]
  39. Expression analysis of SIX3 and SIX6 in human tissues reveals differences in expression and a novel correlation between the expression of SIX3 and the genes encoding isocitrate dehyhrogenase and cadherin 18. Aijaz, S., Allen, J., Tregidgo, R., van Heyningen, V., Hanson, I., Clark, B.J. Genomics (2005) [Pubmed]
  40. Calcitonin receptor-like receptor: identification and distribution in human peripheral tissues. Hagner, S., Stahl, U., Knoblauch, B., McGregor, G.P., Lang, R.E. Cell Tissue Res. (2002) [Pubmed]
  41. Determination of apalcillin and its metabolites in human body fluids by high-pressure liquid chromatography. Borner, K., Lode, H., Elvers, A. Antimicrob. Agents Chemother. (1982) [Pubmed]
  42. Comparison of enzyme immunoassay and latex agglutination methods for detection of Cryptococcus neoformans antigen. Scott, E.N., Muchmore, H.G., Felton, F.G. Am. J. Clin. Pathol. (1980) [Pubmed]
  43. A complex of the soluble interleukin-6 receptor and interleukin-6 is internalized via the signal transducer gp130. Graeve, L., Korolenko, T.A., Hemmann, U., Weiergräber, O., Dittrich, E., Heinrich, P.C. FEBS Lett. (1996) [Pubmed]
  44. Deep brain stimulation for dystonia confirming a somatotopic organization in the globus pallidus internus. Vayssiere, N., van der Gaag, N., Cif, L., Hemm, S., Verdier, R., Frerebeau, P., Coubes, P. J. Neurosurg. (2004) [Pubmed]
  45. Measurement of bactericidal/permeability-increasing protein in human body fluids by sandwich ELISA. White, M.L., Ma, J.K., Birr, C.A., Trown, P.W., Carroll, S.F. J. Immunol. Methods (1994) [Pubmed]
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