Chemical Compound Review:
Efonidipine 2-(benzyl-phenyl-amino)ethyl 5-(5,5...
Synonyms:
AGN-PC-00FP0M, AC-389, CHEMBL2074922, AC1L3OBH, ACT06293, ...
- Vascular effects of calcium channel antagonists: new evidence. Richard, S. Drugs (2005)
- Effect of efonidipine and ACE inhibitors on proteinuria in human hypertension with renal impairment. Hayashi, K., Kumagai, H., Saruta, T. Am. J. Hypertens. (2003)
- Calcium antagonist inhibits glomerular cell apoptosis and injuries of L-NAME exacerbated nephrosclerosis in SHR. Watanabe, S., Ono, H., Ishimitsu, T., Matsuoka, H., Ono, Y., Fujimori, T. Hypertens. Res. (2000)
- Effects of efonidipine on platelet and monocyte activation markers in hypertensive patients with and without type 2 diabetes mellitus. Nomura, S., Kanazawa, S., Fukuhara, S. Journal of human hypertension. (2002)
- Divergent renal vasodilator action of L- and T-type calcium antagonists in vivo. Honda, M., Hayashi, K., Matsuda, H., Kubota, E., Tokuyama, H., Okubo, K., Takamatsu, I., Ozawa, Y., Saruta, T. J. Hypertens. (2001)
- Identification of R(-)-isomer of efonidipine as a selective blocker of T-type Ca2+ channels. Furukawa, T., Miura, R., Honda, M., Kamiya, N., Mori, Y., Takeshita, S., Isshiki, T., Nukada, T. Br. J. Pharmacol. (2004)
- Divergent natriuretic action of calcium channel antagonists in mongrel dogs: renal haemodynamics as a determinant of natriuresis. Honda, M., Hayashi, K., Matsuda, H., Kubota, E., Tokuyama, H., Okubo, K., Ozawa, Y., Saruta, T. Clin. Sci. (2001)
- Inhibition of myocardial L- and T-type Ca2+ currents by efonidipine: possible mechanism for its chronotropic effect. Masumiya, H., Shijuku, T., Tanaka, H., Shigenobu, K. Eur. J. Pharmacol. (1998)
- Effects of Ca2+ channel antagonists on sinus node: prolongation of late phase 4 depolarization by efonidipine. Masumiya, H., Tanaka, H., Shigenobu, K. Eur. J. Pharmacol. (1997)
- Effects of benidipine in a rat model of experimental angina. Ikeda, J., Matsubara, M., Yao, K. Yakugaku Zasshi (2006)
- Role of actions of calcium antagonists on efferent arterioles--with special references to glomerular hypertension. Hayashi, K., Ozawa, Y., Fujiwara, K., Wakino, S., Kumagai, H., Saruta, T. American journal of nephrology. (2003)
- Disparate effects of calcium antagonists on renal microcirculation. Hayashi, K., Nagahama, T., Oka, K., Epstein, M., Saruta, T. Hypertens. Res. (1996)
- Renal effects of efonidipine hydrochloride, a new calcium antagonist, in spontaneously hypertensive rats with glomerular injury. Kawabata, M., Ogawa, T., Han, W.H., Takabatake, T. Clin. Exp. Pharmacol. Physiol. (1999)
- The voltage-dependent non-selective cation channel sensitive to the L-type calcium channel blocker efonidipine regulates Ca2+ influx in brain vascular smooth muscle cells. Matsuoka, T., Nishizaki, T., Nomura, T. Biochem. Biophys. Res. Commun. (1997)
- Effects of efonidipine hydrochloride on cholesterol esterification mediated by beta-very low density lipoprotein in J774 macrophages. Kitahara, M., Toyoda, K., Yamashita, T., Sakashita, M., Tanaka, S., Saito, Y. Jpn. J. Pharmacol. (1995)
- Inhibitory effects of calcium antagonists on mitochondrial swelling induced by lipid peroxidation or arachidonic acid in the rat brain in vitro. Takei, M., Hiramatsu, M., Mori, A. Neurochem. Res. (1994)
- Frequency-dependent blockade of T-type Ca2+ current by efonidipine in cardiomyocytes. Masumiya, H., Kase, J., Tanaka, Y., Tanaka, H., Shigenobu, K. Life Sci. (2000)
- Possible requirement of phosphonate moiety for efonidipine effects on the sino-atrial node action potential. Masumiya, H., Matsuda, T., Tanaka, Y., Tanaka, H., Shigenobu, K. Life Sci. (2000)
- Blocking T-type Ca2+ channels with efonidipine decreased plasma aldosterone concentration in healthy volunteers. Okayama, S., Imagawa, K., Naya, N., Iwama, H., Somekawa, S., Kawata, H., Horii, M., Nakajima, T., Uemura, S., Saito, Y. Hypertens. Res. (2006)
- Effects of efonidipine hydrochloride on renal arteriolar diameters in spontaneously hypertensive rats. Nakamura, M., Notoya, M., Kohda, Y., Yamashita, J., Takashita, Y., Gemba, M. Hypertens. Res. (2002)
- Divergent action of calcium channel blockers on ATP-binding cassette protein expression. Hasegawa, K., Wakino, S., Kanda, T., Yoshioka, K., Tatematsu, S., Homma, K., Takamatsu, I., Sugano, N., Hayashi, K. J. Cardiovasc. Pharmacol. (2005)
- Efonidipine, a long-acting dihydropyridine derivative, attenuates coronary vasoconstriction induced by endothelin-1 in dogs. Yokoyama, T., Ichihara, K., Abiko, Y. Jpn. J. Pharmacol. (1996)
- Inhibitory effect of efonidipine on aldosterone synthesis and secretion in human adrenocarcinoma (H295R) cells. Imagawa, K., Okayama, S., Takaoka, M., Kawata, H., Naya, N., Nakajima, T., Horii, M., Uemura, S., Saito, Y. J. Cardiovasc. Pharmacol. (2006)
- Effects of the antihypertensive drug efonidipine hydrochloride on albuminuria and renal histopathology in young spontaneously hypertensive rats with diabetes. Takeda, M., Shou, I., Tomino, Y. Gen. Pharmacol. (1998)