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Chemical Compound Review

Fanasil     4-amino-N-(5,6- dimethoxypyrimidin-4...

Synonyms: Fanzil, Sulfadoxin, SULFADOXINE, Sulformetoxine, Sulphormetoxin, ...
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Disease relevance of SULFADOXINE


High impact information on SULFADOXINE


Chemical compound and disease context of SULFADOXINE


Biological context of SULFADOXINE


Anatomical context of SULFADOXINE


Associations of SULFADOXINE with other chemical compounds


Gene context of SULFADOXINE


Analytical, diagnostic and therapeutic context of SULFADOXINE


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  15. Allelic exchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxine-resistant malaria. Triglia, T., Wang, P., Sims, P.F., Hyde, J.E., Cowman, A.F. EMBO J. (1998) [Pubmed]
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  17. In vivo selection for a specific genotype of dihydropteroate synthetase of Plasmodium falciparum by pyrimethamine-sulfadoxine but not chlorproguanil-dapsone treatment. Curtis, J., Duraisingh, M.T., Warhurst, D.C. J. Infect. Dis. (1998) [Pubmed]
  18. Effect of a single oral dose of Fansidar on the pharmacokinetics of halofantrine in healthy volunteers: a preliminary report. Hombhanje, F.W. British journal of clinical pharmacology. (2000) [Pubmed]
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  20. Adoptive transfer of resistance to Plasmodium berghei with spleen cells and serum from Fansidar-cured mice. Ferraroni, J.J., Speer, C.A. Infect. Immun. (1982) [Pubmed]
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  22. Sulphadoxine concentrations in plasma, red blood cells and whole blood in healthy and Plasmodium falciparum malaria cases after treatment with Fansidar using high-performance liquid chromatography. Dua, V.K., Sarin, R., Sharma, V.P. Journal of pharmaceutical and biomedical analysis. (1994) [Pubmed]
  23. The chemotherapy of rodent malaria, XXXII. The influence of p-aminobenzoic acid on the transmission of Plasmodium yoelii and P. berghei by Anopheles stephensi. Peters, W., Ramkaran, A.E. Ann. Trop. Med. Parasitol. (1980) [Pubmed]
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  26. Pneumocystis jiroveci dihydropteroate synthase polymorphisms confer resistance to sulfadoxine and sulfanilamide in Saccharomyces cerevisiae. Meneau, I., Sanglard, D., Bille, J., Hauser, P.M. Antimicrob. Agents Chemother. (2004) [Pubmed]
  27. New micromethod to study the effect of antimicrobial agents on Toxoplasma gondii: comparison of sulfadoxine and sulfadiazine individually and in combination with pyrimethamine and study of clindamycin, metronidazole, and cyclosporin A. Mack, D.G., McLeod, R. Antimicrob. Agents Chemother. (1984) [Pubmed]
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  30. Determination of sulfadoxine concentrations in whole blood using C18 solid-phase extraction, sodium dodecyl sulfate and dimethylaminocinnamaldehyde. Green, M.D., Mount, D.L., Todd, G.D. The Analyst. (1995) [Pubmed]
  31. Effect of pyrimethamine and sulphadoxine on human lymphocyte proliferation. Bygbjerg, I.C., Odum, N., Theander, T.G. Trans. R. Soc. Trop. Med. Hyg. (1986) [Pubmed]
  32. Determination of pyrimethamine in human plasma after administration of fansidar of fansidar-mefloquine by means of high-performance liquid chromatography with fluorescence detection. Timm, U., Weidekamm, E. J. Chromatogr. (1982) [Pubmed]
  33. High-performance liquid chromatography determination of pyrimethamine, dapsone, monoacetyldapsone, sulfadoxine, and N-acetyl-sulfadoxine after rapid solid-phase extraction. Eljaschewitsch, J., Padberg, J., Schürmann, D., Ruf, B. Therapeutic drug monitoring. (1996) [Pubmed]
  34. The disposition of oral and intramuscular pyrimethamine/sulphadoxine in Kenyan children with high parasitaemia but clinically non-severe falciparum malaria. Winstanley, P.A., Watkins, W.M., Newton, C.R., Nevill, C., Mberu, E., Warn, P.A., Waruiru, C.M., Mwangi, I.N., Warrell, D.A., Marsh, K. British journal of clinical pharmacology. (1992) [Pubmed]
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