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Chemical Compound Review

Gantanol     4-amino-N-(5-methyl-1,2- oxazol-3...

Synonyms: Gamazole, Bactrimel, Metoxal, Radonil, Septran, ...
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Disease relevance of sulfamethoxazole


High impact information on sulfamethoxazole


Chemical compound and disease context of sulfamethoxazole


Biological context of sulfamethoxazole


Anatomical context of sulfamethoxazole


Associations of sulfamethoxazole with other chemical compounds


Gene context of sulfamethoxazole


Analytical, diagnostic and therapeutic context of sulfamethoxazole


  1. Successful chemoprophylaxis for Pneumocystis carinii pneumonitis. Hughes, W.T., Kuhn, S., Chaudhary, S., Feldman, S., Verzosa, M., Aur, R.J., Pratt, C., George, S.L. N. Engl. J. Med. (1977) [Pubmed]
  2. Antibacterial synergism: a proposal for chemotherapeutic potentiation between trimethoprim and sulfamethoxazole. Poe, M. Science (1976) [Pubmed]
  3. Three vs 10 days of trimethoprim/sulfamethoxazole for acute maxillary sinusitis. Rosborough, T.K., Rierach, C.A. JAMA (1995) [Pubmed]
  4. Safety and efficacy of sulfamethoxazole and trimethoprim chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS. Fischl, M.A., Dickinson, G.M., La Voie, L. JAMA (1988) [Pubmed]
  5. Investigation of multidrug-resistant Salmonella serotype typhimurium DT104 infections linked to raw-milk cheese in Washington State. Villar, R.G., Macek, M.D., Simons, S., Hayes, P.S., Goldoft, M.J., Lewis, J.H., Rowan, L.L., Hursh, D., Patnode, M., Mead, P.S. JAMA (1999) [Pubmed]
  6. Three vs 10 days of trimethoprim/sulfamethoxazole for acute maxillary sinusitis. Sawyer, J., Stryer, D., Rydberg, M., Polstein, B. JAMA (1995) [Pubmed]
  7. Prophylaxis of recurrent urinary tract infection in female patients. Efficacy of low-dose, thrice-weekly therapy with trimethoprim-sulfamethoxazole. Harding, G.K., Buckwold, F.J., Marrie, T.J., Thompson, L., Light, R.B., Ronald, A.R. JAMA (1979) [Pubmed]
  8. Direct, MHC-dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones. Schnyder, B., Mauri-Hellweg, D., Zanni, M., Bettens, F., Pichler, W.J. J. Clin. Invest. (1997) [Pubmed]
  9. Nonfluid therapy and selected chemoprophylaxis of acute diarrhea. Du Pont, H.L. Am. J. Med. (1985) [Pubmed]
  10. Site-specific integration of the conjugal Vibrio cholerae SXT element into prfC. Hochhut, B., Waldor, M.K. Mol. Microbiol. (1999) [Pubmed]
  11. Use of norfloxacin in the treatment of acute diarrheal disease. Dupont, H.L., Corrado, M.L., Sabbaj, J. Am. J. Med. (1987) [Pubmed]
  12. A multicenter study of lomefloxacin and trimethoprim/sulfamethoxazole in the treatment of uncomplicated acute pyelonephritis. Mouton, Y., Ajana, F., Chidiac, C., Capron, M.H., Home, P., Masquelier, A.M. Am. J. Med. (1992) [Pubmed]
  13. Serum lactate dehydrogenase levels in adults and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex: possible indicator of B cell lymphoproliferation and disease activity. Effect of intravenous gammaglobulin on enzyme levels. Silverman, B.A., Rubinstein, A. Am. J. Med. (1985) [Pubmed]
  14. A common polymorphism associated with antibiotic-induced cardiac arrhythmia. Sesti, F., Abbott, G.W., Wei, J., Murray, K.T., Saksena, S., Schwartz, P.J., Priori, S.G., Roden, D.M., George, A.L., Goldstein, S.A. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  15. Nonhomogeneous labeling of liver extra-mitochondrial acetyl-CoA. Implications for the probing of lipogenic acetyl-CoA via drug acetylation and for the production of acetate by the liver. Zhang, Y., Agarwal, K.C., Beylot, M., Soloviev, M.V., David, F., Reider, M.W., Anderson, V.E., Tserng, K.Y., Brunengraber, H. J. Biol. Chem. (1994) [Pubmed]
  16. Selective inhibition of human neutrophil chemotaxis to N-formyl-methionyl-leucyl-phenylalanine by sulfones. Harvath, L., Yancey, K.B., Katz, S.I. J. Immunol. (1986) [Pubmed]
  17. Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole. Moore, K.H., Yuen, G.J., Raasch, R.H., Eron, J.J., Martin, D., Mydlow, P.K., Hussey, E.K. Clin. Pharmacol. Ther. (1996) [Pubmed]
  18. Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation. Naisbitt, D.J., Farrell, J., Gordon, S.F., Maggs, J.L., Burkhart, C., Pichler, W.J., Pirmohamed, M., Park, B.K. Mol. Pharmacol. (2002) [Pubmed]
  19. Bullous esophageal lesions due to cotrimoxazole: an immune-mediated process? Heer, M., Altorfer, J., Burger, H.R., Wälti, M. Gastroenterology (1985) [Pubmed]
  20. Reversal of dementia associated with Whipple's disease by trimethoprim-sulfamethoxazole, drugs that penetrate the blood-brain barrier. Ryser, R.J., Locksley, R.M., Eng, S.C., Dobbins, W.O., Schoenknecht, F.D., Rubin, C.E. Gastroenterology (1984) [Pubmed]
  21. Ciprofloxacin versus trimethoprim/sulfamethoxazole for prophylaxis of bacterial infections in bone marrow transplant recipients: a randomized, controlled trial. Lew, M.A., Kehoe, K., Ritz, J., Antman, K.H., Nadler, L., Kalish, L.A., Finberg, R. J. Clin. Oncol. (1995) [Pubmed]
  22. Randomized controlled trial comparing trimethoprim/sulfamethoxazole and trimethoprim for infection prophylaxis in hospitalized granulocytopenic patients. Bow, E.J., Louie, T.J., Riben, P.D., McNaughton, R.D., Harding, G.K., Ronald, A.R. Am. J. Med. (1984) [Pubmed]
  23. Interaction of sulfonamide and sulfone compounds with Toxoplasma gondii dihydropteroate synthase. Allegra, C.J., Boarman, D., Kovacs, J.A., Morrison, P., Beaver, J., Chabner, B.A., Masur, H. J. Clin. Invest. (1990) [Pubmed]
  24. Hyperkalemia in hospitalized patients treated with trimethoprim-sulfamethoxazole. Alappan, R., Perazella, M.A., Buller, G.K. Ann. Intern. Med. (1996) [Pubmed]
  25. Inhibition of cytokine production and interference in IL-2 receptor-mediated Jak-Stat signaling by the hydroxylamine metabolite of sulfamethoxazole. Hess, D.A., O'Leary, E.F., Lee, J.T., Almawi, W.Y., Madrenas, J., Rieder, M.J. FASEB J. (2001) [Pubmed]
  26. Interaction of sulfonamide derivatives with the TCR of sulfamethoxazole-specific human alpha beta+ T cell clones. von Greyerz, S., Zanni, M.P., Frutig, K., Schnyder, B., Burkhart, C., Pichler, W.J. J. Immunol. (1999) [Pubmed]
  27. Safety of dapsone as Pneumocystis carinii pneumonia prophylaxis in human immunodeficiency virus-infected patients with allergy to trimethoprim/sulfamethoxazole. Beumont, M.G., Graziani, A., Ubel, P.A., MacGregor, R.R. Am. J. Med. (1996) [Pubmed]
  28. Molecular characterization of multidrug-resistant Salmonella enterica subsp. enterica serovar Typhimurium isolates from swine. Gebreyes, W.A., Altier, C. J. Clin. Microbiol. (2002) [Pubmed]
  29. Trimethoprim and sulfamethoxazole are selective inhibitors of CYP2C8 and CYP2C9, respectively. Wen, X., Wang, J.S., Backman, J.T., Laitila, J., Neuvonen, P.J. Drug Metab. Dispos. (2002) [Pubmed]
  30. Promoter strength of folic acid synthesis genes affects sulfa drug resistance in Saccharomyces cerevisiae. Iliades, P., Berglez, J., Meshnick, S., Macreadie, I. Microb. Drug Resist. (2003) [Pubmed]
  31. Exposure of mice to the nitroso metabolite of sulfamethoxazole stimulates interleukin 5 production by CD4+ T-cells. Hopkins, J.E., Naisbitt, D.J., Humphreys, N., Dearman, R.J., Kimber, I., Park, B.K. Toxicology (2005) [Pubmed]
  32. Persistence of sulphonamide resistance in Escherichia coli in the UK despite national prescribing restriction. Enne, V.I., Livermore, D.M., Stephens, P., Hall, L.M. Lancet (2001) [Pubmed]
  33. Prolonged cholestasis due to trimethoprim sulfamethoxazole. Kowdley, K.V., Keeffe, E.B., Fawaz, K.A. Gastroenterology (1992) [Pubmed]
  34. Oral trimethoprim/sulfamethoxazole in attempt to prevent infection after induction chemotherapy for acute leukemia. Henry, S.A., Armstrong, D., Kempin, S., Gee, T., Arlin, Z., Clarkson, B. Am. J. Med. (1984) [Pubmed]
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