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Chemical Compound Review

AC1NSWGJ     (3S,8S,10R,13S)-10,13,17- trimethyl-17-(6...

Synonyms:
 
 
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Disease relevance of 7alpha-Hydroxycholesterol

 

High impact information on 7alpha-Hydroxycholesterol

 

Chemical compound and disease context of 7alpha-Hydroxycholesterol

 

Biological context of 7alpha-Hydroxycholesterol

 

Anatomical context of 7alpha-Hydroxycholesterol

 

Associations of 7alpha-Hydroxycholesterol with other chemical compounds

 

Gene context of 7alpha-Hydroxycholesterol

 

Analytical, diagnostic and therapeutic context of 7alpha-Hydroxycholesterol

References

  1. Cholestyramine loading test to assess hepatic reserve for bile acid synthesis in patients with chronic liver diseases. Kuroki, S., Naito, T., Okamoto, S., Sakai, H., Yamashita, H., Chijiiwa, K., Tanaka, M. Gastroenterology (1997) [Pubmed]
  2. Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway. Del Puppo, M., Kienle, M.G., Petroni, M.L., Crosignani, A., Podda, M. J. Lipid Res. (1998) [Pubmed]
  3. Ceramide generation occurring during 7beta-hydroxycholesterol- and 7-ketocholesterol-induced apoptosis is caspase independent and is not required to trigger cell death. Miguet, C., Monier, S., Bettaieb, A., Athias, A., Besséde, G., Laubriet, A., Lemaire, S., Néel, D., Gambert, P., Lizard, G. Cell Death Differ. (2001) [Pubmed]
  4. Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. Meir, K., Kitsberg, D., Alkalay, I., Szafer, F., Rosen, H., Shpitzen, S., Avi, L.B., Staels, B., Fievet, C., Meiner, V., Björkhem, I., Leitersdorf, E. J. Biol. Chem. (2002) [Pubmed]
  5. Cholesterol binding to cytochrome P450 7A1, a key enzyme in bile acid biosynthesis. Mast, N., Graham, S.E., Andersson, U., Bjorkhem, I., Hill, C., Peterson, J., Pikuleva, I.A. Biochemistry (2005) [Pubmed]
  6. Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain. Mast, N., Norcross, R., Andersson, U., Shou, M., Nakayama, K., Bjorkhem, I., Pikuleva, I.A. Biochemistry (2003) [Pubmed]
  7. In nonhepatic cells, cholesterol 7alpha-hydroxylase induces the expression of genes regulating cholesterol biosynthesis, efflux, and homeostasis. Spitsen, G.M., Dueland, S., Krisans, S.K., Slattery, C.J., Miyake, J.H., Davis, R.A. J. Lipid Res. (2000) [Pubmed]
  8. Analysis of oxidative processes and of myelin figures formation before and after the loss of mitochondrial transmembrane potential during 7beta-hydroxycholesterol and 7-ketocholesterol-induced apoptosis: comparison with various pro-apoptotic chemicals. Miguet-Alfonsi, C., Prunet, C., Monier, S., Bessède, G., Lemaire-Ewing, S., Berthier, A., Ménétrier, F., Néel, D., Gambert, P., Lizard, G. Biochem. Pharmacol. (2002) [Pubmed]
  9. Vitamin E status in patients with liver cirrhosis: normal or deficient? Look, M.P., Reichel, C., von Falkenhausen, M., Hahn, C., Stockinger, K., von Bergmann, K., Rao, G.S., Spengler, U., Sauerbruch, T. Metab. Clin. Exp. (1999) [Pubmed]
  10. Serum 7alpha-hydroxycholesterol levels during liver regeneration after hepatectomy in humans. Nakamura, K., Chijiiwa, K., Kuroki, S., Naito, T., Mizuta, A., Tanaka, M. Hepatogastroenterology (2003) [Pubmed]
  11. The use of [7alpha-3H]- and [7alpha, 7beta-3H]cholesterol in the enzymic assay of cholesterol 7alpha-hydroxylase. Johnson, D.B., Tyor, M.P., Lack, L. J. Lipid Res. (1976) [Pubmed]
  12. Effects of drugs and sterols on cholesterol 7 alpha-hydroxylase activity in rat liver microsomes. Schwartz, M.A., Margolis, S. J. Lipid Res. (1983) [Pubmed]
  13. Conversion of 7alpha-hydroxycholesterol and 7alpha-hydroxy-beta-sitosterol to 3alpha, 7alpha-dihydroxy- and 3alpha, 7alpha, 12alpha-trihydroxy-5beta-steroids in vitro. Aringer, L. J. Lipid Res. (1975) [Pubmed]
  14. Localization of the interference of ascorbic acid deficiency with bile acid biogenesis. Ginter, E., Ozdín, L., Nemec, R. Physiologia Bohemoslovaca. (1977) [Pubmed]
  15. Species differences among various rodents in the conversion of 7alpha-hydroxycholesterol in liver microsomes. Maeda, Y., Shinohara, A., Koshimoto, C., Chijiiwa, K. Steroids (2006) [Pubmed]
  16. Simultaneous evaluation of HMG-CoA reductase and cholesterol 7alpha-hydroxylase activities by electrospray tandem MS. Ndong-Akoume, M.Y., Mignault, D., Perwaiz, S., Plaa, G.L., Yousef, I.M. Lipids (2002) [Pubmed]
  17. Effects of CYP7A1 overexpression on cholesterol and bile acid homeostasis. Pandak, W.M., Schwarz, C., Hylemon, P.B., Mallonee, D., Valerie, K., Heuman, D.M., Fisher, R.A., Redford, K., Vlahcevic, Z.R. Am. J. Physiol. Gastrointest. Liver Physiol. (2001) [Pubmed]
  18. High circulating levels of 7beta- and 7alpha-hydroxycholesterol and presence of apoptotic and oxidative markers in arterial lesions of normocholesterolemic atherosclerotic patients undergoing endarterectomy. Prunet, C., Petit, J.M., Ecarnot-Laubriet, A., Athias, A., Miguet-Alfonsi, C., Rohmer, J.F., Steinmetz, E., Néel, D., Gambert, P., Lizard, G. Pathol. Biol. (2006) [Pubmed]
 
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