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MeSH Review


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Disease relevance of Sigmodontinae


High impact information on Sigmodontinae


Chemical compound and disease context of Sigmodontinae


Biological context of Sigmodontinae


Anatomical context of Sigmodontinae


Associations of Sigmodontinae with chemical compounds


Gene context of Sigmodontinae

  • The researchers managed already to express human CFTR gene in vivo in cotton rats lungs through the viral delivery system [29].
  • In this study, the somatostatin analogue octreotide was given to female cotton rats to prevent carcinoma development caused by hypergastrinaemia [21].
  • Structural comparison of hamster p35 and p40 at the protein level showed the highest homologies with each counterpart of sigmodon (hispid cotton rat) [30].
  • Rats, like other crepuscular animals, have excellent auditory capacities and they discriminate well between different sounds [Heffner HE, Heffner RS, Hearing in two cricetid rodents: wood rats (Neotoma floridana) and grasshopper mouse (Onychomys leucogaster). J Comp Psychol 1985;99(3):275-88] [31].
  • To enhance the usefulness of this model, four immunoglobulins in Sigmodon serum were characterized (IgG1, IgG2, IgA, IgM) and antisera specific for each immunoglobulin were made [32].

Analytical, diagnostic and therapeutic context of Sigmodontinae


  1. Role of early genes in pathogenesis of adenovirus pneumonia. Ginsberg, H.S., Horswood, R.L., Chanock, R.M., Prince, G.A. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  2. Efficacy and safety studies of a recombinant chimeric respiratory syncytial virus FG glycoprotein vaccine in cotton rats. Prince, G.A., Capiau, C., Deschamps, M., Fabry, L., Garçon, N., Gheysen, D., Prieels, J.P., Thiry, G., Van Opstal, O., Porter, D.D. J. Virol. (2000) [Pubmed]
  3. Pathogenesis of adenovirus type 5 pneumonia in cotton rats (Sigmodon hispidus). Prince, G.A., Porter, D.D., Jenson, A.B., Horswood, R.L., Chanock, R.M., Ginsberg, H.S. J. Virol. (1993) [Pubmed]
  4. Attenuated Salmonella enterica serovar Typhi and Shigella flexneri 2a strains mucosally deliver DNA vaccines encoding measles virus hemagglutinin, inducing specific immune responses and protection in cotton rats. Pasetti, M.F., Barry, E.M., Losonsky, G., Singh, M., Medina-Moreno, S.M., Polo, J.M., Ulmer, J., Robinson, H., Sztein, M.B., Levine, M.M. J. Virol. (2003) [Pubmed]
  5. In vivo transfer of the human cystic fibrosis transmembrane conductance regulator gene to the airway epithelium. Rosenfeld, M.A., Yoshimura, K., Trapnell, B.C., Yoneyama, K., Rosenthal, E.R., Dalemans, W., Fukayama, M., Bargon, J., Stier, L.E., Stratford-Perricaudet, L. Cell (1992) [Pubmed]
  6. Hyperimmune globulins in prevention and treatment of respiratory syncytial virus infections. Hemming, V.G., Prince, G.A., Groothuis, J.R., Siber, G.R. Clin. Microbiol. Rev. (1995) [Pubmed]
  7. ECL-cell derived gastric cancer in male cotton rats dosed with the H2-blocker loxtidine. Fossmark, R., Martinsen, T.C., Bakkelund, K.E., Kawase, S., Waldum, H.L. Cancer Res. (2004) [Pubmed]
  8. In vitro metabolism and mutagenic activation of 2-acetylaminofluorene by subcellular liver fractions from Cotton rats. Schut, H.A., Thorgeirsson, S.S. Cancer Res. (1978) [Pubmed]
  9. Respiratory syncytial virus (RSV) infection induces cyclooxygenase 2: a potential target for RSV therapy. Richardson, J.Y., Ottolini, M.G., Pletneva, L., Boukhvalova, M., Zhang, S., Vogel, S.N., Prince, G.A., Blanco, J.C. J. Immunol. (2005) [Pubmed]
  10. Respiratory syncytial virus infection in cyclophosphamide-treated cotton rats. Johnson, R.A., Prince, G.A., Suffin, S.C., Horswood, R.L., Chanock, R.M. Infect. Immun. (1982) [Pubmed]
  11. Suppression of respiratory syncytial virus infection in cotton rats by bis(5-amidino-2-benzimidazolyl)methane. Tidwell, R.R., Geratz, J.D., Clyde, W.A., Rosenthal, K.U., Dubovi, E.J. Antimicrob. Agents Chemother. (1984) [Pubmed]
  12. Immunoglobulin administration and ribavirin therapy: efficacy in respiratory syncytial virus infection of the cotton rat. Gruber, W.C., Wilson, S.Z., Throop, B.J., Wyde, P.R. Pediatr. Res. (1987) [Pubmed]
  13. Some effects of hydrocortisone on the early development of the rat cotton pellet granuloma. Freeman, P.C., Mangan, F.R., Watkins, D.K. Biochem. Pharmacol. (1979) [Pubmed]
  14. Use of chlorhexidine gluconate to prevent bone resorption in the rice rat. Leonard, E.P., Mandel, E.J. J. Dent. Res. (1979) [Pubmed]
  15. Trans-complementation of E1-deleted adenovirus: a new vector to reduce the possibility of codissemination of wild-type and recombinant adenoviruses. Imler, J.L., Bout, A., Dreyer, D., Dieterlé, A., Schultz, H., Valerio, D., Mehtali, M., Pavirani, A. Hum. Gene Ther. (1995) [Pubmed]
  16. In vivo evaluation of the safety of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator cDNA to the lung. Yei, S., Mittereder, N., Wert, S., Whitsett, J.A., Wilmott, R.W., Trapnell, B.C. Hum. Gene Ther. (1994) [Pubmed]
  17. Cloning, expression and purification of recombinant cotton rat interleukin-5. Houard, S., Jacquet, A., Haumont, M., Daminet, V., Milican, F., Glineur, F., Bollen, A. Gene (2000) [Pubmed]
  18. Microsatellite DNA markers for the study of Allegheny woodrat (Neotoma magister) populations and cross-species amplification in the genus neotoma. Castleberry, S.B., King, T.L., Wood, P.B., Ford, W.M. Mol. Ecol. (2000) [Pubmed]
  19. Molecular systematics of the genus Neotoma. Edwards, C.W., Bradley, R.D. Mol. Phylogenet. Evol. (2002) [Pubmed]
  20. Persistence of replication-deficient adenovirus-mediated gene transfer in lungs of immune-deficient (nu/nu) mice. Zsengeller, Z.K., Wert, S.E., Hull, W.M., Hu, X., Yei, S., Trapnell, B.C., Whitsett, J.A. Hum. Gene Ther. (1995) [Pubmed]
  21. Spontaneous enterochromaffin-like cell carcinomas in cotton rats (Sigmodon hispidus) are prevented by a somatostatin analogue. Fossmark, R., Martinsen, T.C., Torp, S.H., Kawase, S., Sandvik, A.K., Waldum, H.L. Endocr. Relat. Cancer (2004) [Pubmed]
  22. Monophosphoryl lipid A adjuvant reverses a principal histologic parameter of formalin-inactivated respiratory syncytial virus vaccine-induced disease. Prince, G.A., Denamur, F., Deschamps, M., Garçon, N., Prieels, J.P., Slaoui, M., Thiriart, C., Porter, D.D. Vaccine (2001) [Pubmed]
  23. The cotton rat: an underutilized animal model for human infectious diseases can now be exploited using specific reagents to cytokines, chemokines, and interferons. Blanco, J.C., Pletneva, L., Boukhvalova, M., Richardson, J.Y., Harris, K.A., Prince, G.A. J. Interferon Cytokine Res. (2004) [Pubmed]
  24. Experimental Helicobacter pylori infection induces antral-predominant, chronic active gastritis in hispid cotton rats (Sigmodon hispidus). Mähler, M., Heidtmann, W., Niewiesk, S., Gruber, A., Fossmark, R., Beil, W., Hedrich, H., Wagner, S. Helicobacter (2005) [Pubmed]
  25. In vivo selection of respiratory syncytial viruses resistant to palivizumab. Zhao, X., Sullender, W.M. J. Virol. (2005) [Pubmed]
  26. Vaccination of cotton rats with a chimeric FG glycoprotein of human respiratory syncytial virus induces minimal pulmonary pathology on challenge. Wathen, M.W., Kakuk, T.J., Brideau, R.J., Hausknecht, E.C., Cole, S.L., Zaya, R.M. J. Infect. Dis. (1991) [Pubmed]
  27. Responsiveness of pineal N-acetyltransferase and melatonin in the cotton rat exposed to either artificial or natural light at night. Nürnberger, F., Joshi, B.N., Heinzeller, T., Milin, J., Reiter, R.J. J. Pineal Res. (1985) [Pubmed]
  28. Use of cotton rats to evaluate the efficacy of antivirals in treatment of measles virus infections. Wyde, P.R., Moore-Poveda, D.K., De Clercq, E., Neyts, J., Matsuda, A., Minakawa, N., Guzman, E., Gilbert, B.E. Antimicrob. Agents Chemother. (2000) [Pubmed]
  29. New perspectives and hope for cure-reflecting recent genetic developments in cystic fibrosis. Midro, A.T., Kulczycki, L.L. Materia medica Polona. Polish journal of medicine and pharmacy. (1992) [Pubmed]
  30. Structure and characterization of hamster IL-12 p35 and p40. Maruyama, K., Takigawa, Y., Akiyama, Y., Hojo, T., Nara-Ashizawa, N., Cheng, J.Y., Watanabe, M., Yamaguchi, K. Mol. Immunol. (2003) [Pubmed]
  31. Auditory cues support place navigation in rats when associated with a visual cue. Rossier, J., Haeberli, C., Schenk, F. Behav. Brain Res. (2000) [Pubmed]
  32. Definition of cotton rat immunoglobulins: sigmodon species differ in expression of IgG isotypes and production of respiratory syncytial virus antibody. Coe, J.E., Prince, G.A. Immunology (1996) [Pubmed]
  33. Oral efficacy of a respiratory syncytial virus inhibitor in rodent models of infection. Cianci, C., Genovesi, E.V., Lamb, L., Medina, I., Yang, Z., Zadjura, L., Yang, H., D'Arienzo, C., Sin, N., Yu, K.L., Combrink, K., Li, Z., Colonno, R., Meanwell, N., Clark, J., Krystal, M. Antimicrob. Agents Chemother. (2004) [Pubmed]
  34. Adenoviral-mediated gene transfer of human surfactant protein B to respiratory epithelial cells. Yei, S., Bachurski, C.J., Weaver, T.E., Wert, S.E., Trapnell, B.C., Whitsett, J.A. Am. J. Respir. Cell Mol. Biol. (1994) [Pubmed]
  35. Serologic evidence of infection with Ehrlichia spp. in wild rodents (Muridae: Sigmodontinae) in the United States. Nicholson, W.L., Muir, S., Sumner, J.W., Childs, J.E. J. Clin. Microbiol. (1998) [Pubmed]
  36. Litomosoides carinii infection in cotton-rats before and after treatment with diethylcarbamazine and suramin: evolution of free serum antigens. Carme, B., Richard-Lenoble, D., Amgar, A., Danis, M., Gentilini, M. Trans. R. Soc. Trop. Med. Hyg. (1982) [Pubmed]
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