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Chemical Compound Review

Dermacid     3H-benzothiazole-2-thione

Synonyms: Kaptaks, Sulfadene, Thiotax, mebetizol, Bantex, ...
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Disease relevance of Zenite special


High impact information on Zenite special


Chemical compound and disease context of Zenite special


Biological context of Zenite special


Associations of Zenite special with other chemical compounds


Gene context of Zenite special

  • PTBP resin and chromium proved to be the 2 principal allergens, but when lesions were localized to the soles, rubber additives, chiefly mercaptobenzothiazole, were the predominant ones [22].

Analytical, diagnostic and therapeutic context of Zenite special


  1. Metabolism of 2-mercaptobenzothiazole by Rhodococcus rhodochrous. Haroune, N., Combourieu, B., Besse, P., Sancelme, M., Kloepfer, A., Reemtsma, T., De Wever, H., Delort, A.M. Appl. Environ. Microbiol. (2004) [Pubmed]
  2. New thioureas and related substances intended for melanoma targeting. Mårs, U., Larsson, B.S. Pigment Cell Res. (1995) [Pubmed]
  3. Hand involvement in allergic contact dermatitis from mercaptobenzothiazole in shoes. Lear, J.T., English, J.S. Contact Derm. (1996) [Pubmed]
  4. Dermatitis from mercaptobenzothiazole in a Foley catheter. Ancona, A., Suárez de la Torre, R., Evia, J.R. Contact Derm. (1985) [Pubmed]
  5. Toxicity of 2-mercaptobenzothiazole towards bacterial growth and respiration. De Wever, H., De Moor, K., Verachtert, H. Appl. Microbiol. Biotechnol. (1994) [Pubmed]
  6. Studies in polyphenol chemistry and bioactivity. 4.(1) Synthesis of trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having all-4beta,8-interflavan connectivity and their inhibition of cancer cell growth through cell cycle arrest. Kozikowski, A.P., Tückmantel, W., Böttcher, G., Romanczyk, L.J. J. Org. Chem. (2003) [Pubmed]
  7. Contamination of injectable solutions with 2-mercaptobenzothiazole leached from rubber closures. Reepmeyer, J.C., Juhl, Y.H. Journal of pharmaceutical sciences. (1983) [Pubmed]
  8. Bikini dermatitis due to mercaptobenzothiazole. Jung, P., Sesztak-Greinecker, G., Wantke, F., Götz, M., Jarisch, R., Hemmer, W. Contact Derm. (2006) [Pubmed]
  9. Survey of sulfur-containing rubber accelerator levels in latex and nitrile exam gloves. Depree, G.J., Bledsoe, T.A., Siegel, P.D. Contact Derm. (2005) [Pubmed]
  10. Synthesis, structural characterization and in vitro cytotoxicity of organotin(IV) derivatives of heterocyclic thioamides, 2-mercaptobenzothiazole, 5-chloro-2-mercaptobenzothiazole, 3-methyl-2-mercaptobenzothiazole and 2-mercaptonicotinic acid. Xanthopoulou, M.N., Hadjikakou, S.K., Hadjiliadis, N., Schürmann, M., Jurkschat, K., Michaelides, A., Skoulika, S., Bakas, T., Binolis, J., Karkabounas, S., Charalabopoulos, K. J. Inorg. Biochem. (2003) [Pubmed]
  11. Isolation, via activity-directed fractionation, of mercaptobenzothiazole and dibenzothiazyl disulfide as 2 allergens responsible for tennis shoe dermatitis. Jung, J.H., McLaughlin, J.L., Stannard, J., Guin, J.D. Contact Derm. (1988) [Pubmed]
  12. Dermatitis from shoes and an amputation prosthesis due to mercaptobenzthiazole and paratertiary butyl formaldehyde resin. Correcher, B.L., Perez, A.G. Contact Derm. (1981) [Pubmed]
  13. Contact dermatitis in black patients. Fisher, A.A. Cutis; cutaneous medicine for the practitioner. (1977) [Pubmed]
  14. Neoprene splinting: dermatological issues. Stern, E.B., Callinan, N., Hank, M., Lewis, E.J., Schousboe, J.T., Ytterberg, S.R. The American journal of occupational therapy. : official publication of the American Occupational Therapy Association. (1998) [Pubmed]
  15. Occupational allergic contact dermatitis from xanthates and carbamates in mining processes. Sasseville, D., Muhn, C.Y., Al-Sowaidi, M. Am. J. Contact Dermatitis (2003) [Pubmed]
  16. Contact sensitizers specifically increase MHC class II expression on murine immature dendritic cells. Herouet, C., Cottin, M., LeClaire, J., Enk, A., Rousset, F. In vitro & molecular toxicology. (2000) [Pubmed]
  17. In vitro induction of polyploidy and chromatid exchanges by culture medium extracts of natural rubbers compounded with 2-mercaptobenzothiazole as a positive control candidate for genotoxicity tests. Matsuoka, A., Isama, K., Tsuchiya, T. Journal of biomedical materials research. Part A. (2005) [Pubmed]
  18. Comparative studies of the sensitization potential of morpholine, 2-mercaptobenzothiazole and 2 of their derivatives in guinea pigs. Wang, X.S., Suskind, R.R. Contact Derm. (1988) [Pubmed]
  19. Stability of the mercaptobenzothiazole compounds. Hansson, C., Agrup, G. Contact Derm. (1993) [Pubmed]
  20. Evaluation of skin symptoms among workers at a Swedish paper mill. Meding, B., Torén, K., Karlberg, A.T., Hagberg, S., Wass, K. Am. J. Ind. Med. (1993) [Pubmed]
  21. Allergy to rubber condom urinals and medical adhesives in male spinal injury patients. Bransbury, A.J. Contact Derm. (1979) [Pubmed]
  22. Contact dermatitis of the feet. Correia, S., Brandão, F.M. Dermatosen in Beruf und Umwelt. Occupation and environment. (1986) [Pubmed]
  23. Extraction of mercaptobenzothiazole compounds from rubber products. Hansson, C., Bergendorff, O., Ezzelarab, M., Sterner, O. Contact Derm. (1997) [Pubmed]
  24. False positive reaction to mercaptobenzthiazole from rubber in eyedrop bottle. Calnan, C.D., Cronin, E. Contact Derm. (1981) [Pubmed]
  25. Identification of causative chemicals of allergic contact dermatitis using a combination of patch testing in patients and chemical analysis. Application to cases from rubber footwear. Kaniwa, M.A., Isama, K., Nakamura, A., Kantoh, H., Itoh, M., Miyoshi, K., Saito, S., Shono, M. Contact Derm. (1994) [Pubmed]
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