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Chemical Compound Review

Edrophonium chloride     ethyl-(3-hydroxyphenyl)- dimethyl-azanium...

Synonyms: Antirex, Enlon, Prestwick_192, Tensilon (TN), CHEMBL1128, ...
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Disease relevance of edrophonium

 

High impact information on edrophonium

 

Chemical compound and disease context of edrophonium

 

Biological context of edrophonium

 

Anatomical context of edrophonium

 

Associations of edrophonium with other chemical compounds

 

Analytical, diagnostic and therapeutic context of edrophonium

  • Due consideration of clinical symptomatology, a Tensilon test, and a trial of immunosuppression may be necessary to establish the diagnosis [21].
  • The tensile and tear strength of carrageenan film from Philippines Eucheuma species were investigated using NEC tensilon universal-testing machine according to American Society for Testing Materials methods [22].
  • METHODS: The patients were studied clinically and with various other tests used in OMG diagnosis (SFEMG, repetitive nerve stimulation, Ab anti AChR titration, tensilon test) [23].
  • A quantitative Tensilon test yeilded a "perverse" response and a needle biopsy indicated Hashimoto's disease [24].
  • After measurement of their baseline phorias and tropias, patients received an intravenous injection of Tensilon via the incremental dose technique until autonomic effects of the drug were noted or until 10 mg was administered [25].

References

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  17. Myasthenia gravis: the effect of Tensilon on the caloric nystagmus response. Photoelectronystagmographic study. Szathmáry, I., Simon, J., Szobor, A., Piffkó, P. ORL J. Otorhinolaryngol. Relat. Spec. (1979) [Pubmed]
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  22. Tensile and tear strength of carrageenan film from Philippine eucheuma species. Briones, A.V., Ambal, W.O., Estrella, R.R., Pangilinan, R., De Vera, C.J., Pacis, R.L., Rodriguez, N., Villanueva, M.A. Mar. Biotechnol. (2004) [Pubmed]
  23. SFEMG in ocular myasthenia gravis diagnosis. Padua, L., Stalberg, E., LoMonaco, M., Evoli, A., Batocchi, A., Tonali, P. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2000) [Pubmed]
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  25. The effect of edrophonium chloride on muscle balance in normal subjects and those with nonmyasthenic strabismus. Siatkowski, R.M., Shah, L., Feuer, W.J. Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society. (1997) [Pubmed]
 
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