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Chemical Compound Review

20,25-Diazacholesterol     17-(3-dimethylaminopropyl- methyl-amino)-10...

Synonyms: Diazasterol, Azacholesterol, CHEMBL172214, SureCN11273267, AC1L1SYM, ...
 
 
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Disease relevance of Azacosterol

 

High impact information on Azacosterol

 

Chemical compound and disease context of Azacosterol

 

Biological context of Azacosterol

 

Anatomical context of Azacosterol

 

Associations of Azacosterol with other chemical compounds

 

Gene context of Azacosterol

 

Analytical, diagnostic and therapeutic context of Azacosterol

References

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  2. Diazacholesterol-induced ichthyosis in the hairless mouse. I. Morphologic, histochemical, and lipid biochemical characterization of a new animal model. Elias, P.M., Lampe, M.A., Chung, J.C., Williams, M.L. Lab. Invest. (1983) [Pubmed]
  3. Transport ATPases of cardiac sarcolemma in 20,25-diazacholesterol induced myopathy. Fiehn, W., Seiler, D., Kuhn, E., Bartels, D. Eur. J. Clin. Invest. (1975) [Pubmed]
  4. Antispermatogenic and antifertility effects of 20,25-diazacholesterol dihydrochloride in mice. Singh, S.K., Chakravarty, S. Reprod. Toxicol. (2003) [Pubmed]
  5. Cholesterol synthesis and nerve regeneration. Heacock, A.M., Klinger, P.D., Seguin, E.B., Agranoff, B.W. J. Neurochem. (1984) [Pubmed]
  6. Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol. Langdon, R., El-Masry, S., Counsell, R.E. J. Lipid Res. (1977) [Pubmed]
  7. Biochemical and morphological effects of 20,25-diazacholesterol on cultured muscle cells. Reddy, N.B., Askanas, V., Oliver, K.L., Lawrence, J.V., Carter, L., Engel, W.K. Biochem. Pharmacol. (1982) [Pubmed]
  8. Membrane desmosterol and the kinetics of the sarcolemmal Na+,K+-ATPase in myotonia induced by 20,25-diazacholesterol. Chalikian, D.M., Barchi, R.L. Exp. Neurol. (1982) [Pubmed]
  9. The effect of a high cholesterol diet on 20,25-diazacholesterol-induced myotonia. Peter, J.B., Stempel, K.E., Dromgoole, S.H., Campion, D.S., Bowman, R.L., Nagatomo, T., Andiman, R.M. Exp. Neurol. (1975) [Pubmed]
  10. Ouabain and tetrodotoxin block the myotonia of skeletal muscle induced with 20,25-diazacholesterol. D'Alonzo, A.J., Argentieri, T.M., McArdle, J.J. J. Pharmacol. Exp. Ther. (1982) [Pubmed]
  11. The effects of taurine on pharmacologically induced myotonia. Conte Camerino, D., De Luca, A., Mambrini, M., Ferrannini, E., Franconi, F., Giotti, A., Bryant, S.H. Muscle Nerve (1989) [Pubmed]
  12. Clofibrate-induced myotonia in rats. Niebrój-Dobosz, I., Kwieciński, H. Acta neurologica Scandinavica. (1983) [Pubmed]
  13. Electron spin resonance studies of an animal model of human congenital myotonia: increased erythrocyte membrane fluidity in rats with 20,25-diazacholesterol-induced myotonia. Butterfield, D.A., Watson, W.E. J. Membr. Biol. (1977) [Pubmed]
  14. Changes of sterol metabolism during 3-methylcholanthrene-induced mouse skin carcinogenesis. Yoshiga, K., Hayashi, T., Takada, K., Okuda, K. Gann = Gan. (1981) [Pubmed]
  15. Membrane fluidity and myotonia: effects of cholesterol and desmosterol on erythrocyte membrane fluidity in rats with 20,25-diazacholesterol-induced myotonia and on phospholipid liposomes. Ashraf, J., Feix, J.B., Butterfield, D.A. Biosci. Rep. (1984) [Pubmed]
  16. Plasma membranes of muscle in experimental myotonia in rats. Niebrój-Dobosz, I., Kwieciński, H., Mrozek, K. J. Neurol. (1976) [Pubmed]
  17. Relation of somal lipid synthesis to the fast axonal transport of protein and lipid. Longo, F.M., Hammerschlag, R. Brain Res. (1980) [Pubmed]
  18. Fast to slow transition induced by experimental myotonia in rat EDL muscle. Salviati, G., Biasia, E., Betto, R., Danieli Betto, D. Pflugers Arch. (1986) [Pubmed]
  19. Ichthyosis induced by cholesterol-lowering drugs. Implications for epidermal cholesterol homeostasis. Williams, M.L., Feingold, K.R., Grubauer, G., Elias, P.M. Archives of dermatology. (1987) [Pubmed]
  20. Effectiveness of twenty, twenty-five diazacholesterol, avian gonadotropin-releasing hormone, and chicken riboflavin carrier protein for inhibiting reproduction in Coturnix quail. Yoder, C.A., Andelt, W.F., Miller, L.A., Johnston, J.J., Goodall, M.J. Poult. Sci. (2004) [Pubmed]
  21. The effects of 6-azacholest-4-en-3 beta-ol-7-one, an inhibitor of cholesterol 7 alpha-hydroxylase, on cholesterol metabolism and bile acid synthesis in primary cultures of rat hepatocytes. Sampson, W.J., Houghton, J.D., Bowers, P., Suffolk, R.A., Botham, K.M., Suckling, C.J., Suckling, K.E. Biochim. Biophys. Acta (1988) [Pubmed]
  22. Myofibrillar protein pattern in experimental myotonia in rats. Niebrój-Dobosz, I., Kwieciński, H., Kamińska, A. J. Neurol. Sci. (1976) [Pubmed]
  23. Motor endplate involvement in the extraocular muscles of the myotonic rat. Pachter, B.R., Eberstein, A. Graefes Arch. Clin. Exp. Ophthalmol. (1986) [Pubmed]
 
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