Gene Review:
Actn1 - actinin, alpha 1
Rattus norvegicus
Synonyms:
Alpha-actinin cytoskeletal isoform, Alpha-actinin-1, F-actin cross-linking protein, Non-muscle alpha-actinin-1
- alpha-Actinin-containing branched microvilli isolated from an ascites adenocarcinoma. Carraway, K.L., Huggins, J.W., Cerra, R.F., Yeltman, D.R., Carraway, C.A. Nature (1980)
- Thymic B lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational autoantibodies reacting with myosin, alpha actinin, or actin. Williams, C.L., Lennon, V.A. J. Exp. Med. (1986)
- Alpha-actinin-containing aggregates in transformed cells are highly dynamic structures. Stickel, S.K., Wang, Y.L. J. Cell Biol. (1987)
- Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts: identification of degradation products and effects on the pCa-force relation. Van Eyk, J.E., Powers, F., Law, W., Larue, C., Hodges, R.S., Solaro, R.J. Circ. Res. (1998)
- Cytoskeletal lesions in anoxic myocardial injury. A conventional and high-voltage electron-microscopic and immunofluorescence study. Ganote, C.E., Vander Heide, R.S. Am. J. Pathol. (1987)
- Calpain activation in plasma membrane bleb formation during tert-butyl hydroperoxide-induced rat hepatocyte injury. Miyoshi, H., Umeshita, K., Sakon, M., Imajoh-Ohmi, S., Fujitani, K., Gotoh, M., Oiki, E., Kambayashi, J., Monden, M. Gastroenterology (1996)
- Restructuring of focal adhesion plaques by PI 3-kinase. Regulation by PtdIns (3,4,5)-p(3) binding to alpha-actinin. Greenwood, J.A., Theibert, A.B., Prestwich, G.D., Murphy-Ullrich, J.E. J. Cell Biol. (2000)
- The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism. Young, P., Gautel, M. EMBO J. (2000)
- Angiotensin II enhances integrin and alpha-actinin expression in adult rat cardiac fibroblasts. Kawano, H., Cody, R.J., Graf, K., Goetze, S., Kawano, Y., Schnee, J., Law, R.E., Hsueh, W.A. Hypertension (2000)
- A multi-mutant herpes simplex virus vector has minimal cytotoxic effects on the distribution of filamentous actin, alpha-actinin 2 and a glutamate receptor in differentiated PC12 cells. Holmes, K.D., Cassam, A.K., Chan, B., Peters, A.A., Weaver, L.C., Dekaban, G.A. J. Neurovirol. (2000)
- Inhibition of phenylephrine-induced cardiac hypertrophy by docosahexaenoic acid. Siddiqui, R.A., Shaikh, S.R., Kovacs, R., Stillwell, W., Zaloga, G. J. Cell. Biochem. (2004)
- Key molecular events in puromycin aminonucleoside nephrosis rats. Guan, N., Ding, J., Deng, J., Zhang, J., Yang, J. Pathol. Int. (2004)
- Brain-specific splicing of alpha-actinin 1 (ACTN1) mRNA. Kremerskothen, J., Teber, I., Wendholt, D., Liedtke, T., Böckers, T.M., Barnekow, A. Biochem. Biophys. Res. Commun. (2002)
- Annexin VI-binding proteins in brain. Interaction of annexin VI with a membrane skeletal protein, calspectin (brain spectrin or fodrin). Watanabe, T., Inui, M., Chen, B.Y., Iga, M., Sobue, K. J. Biol. Chem. (1994)
- Identification of the 52 kDa cytoskeletal-like protein of cytochalasin D-stimulated normal rat kidney (NRK/CD) cells as substrate-associated glycoprotein p52 [plasminogen-activator inhibitor type-1 (PAI-1)]. Expression of p52 (PAI-1) in NRK/CD cells is regulated at the level of mRNA abundance. Higgins, P.J., Ryan, M.P. Biochem. J. (1992)
- Pdlim2, a novel PDZ-LIM domain protein, interacts with alpha-actinins and filamin A. Torrado, M., Senatorov, V.V., Trivedi, R., Fariss, R.N., Tomarev, S.I. Invest. Ophthalmol. Vis. Sci. (2004)
- Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man. Drenckhahn, D., Franke, R.P. Lab. Invest. (1988)
- Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complex. Lehtonen, S., Ryan, J.J., Kudlicka, K., Iino, N., Zhou, H., Farquhar, M.G. Proc. Natl. Acad. Sci. U.S.A. (2005)
- Phospholipase D activity is required for actin stress fiber formation in fibroblasts. Kam, Y., Exton, J.H. Mol. Cell. Biol. (2001)
- In vitro regulation of granulosa cell differentiation. Involvement of cytoskeletal protein expression. Ben-Ze'ev, A., Amsterdam, A. J. Biol. Chem. (1987)
- Drebrin, a development-associated brain protein from rat embryo, causes the dissociation of tropomyosin from actin filaments. Ishikawa, R., Hayashi, K., Shirao, T., Xue, Y., Takagi, T., Sasaki, Y., Kohama, K. J. Biol. Chem. (1994)
- In vivo and in vitro detachment of proximal tubular cells and F-actin damage: consequences for renal function. Van de Water, B., Jaspers, J.J., Maasdam, D.H., Mulder, G.J., Nagelkerke, J.F. Am. J. Physiol. (1994)
- Myocyte redistribution of GRK2 and GRK5 in hypertensive, heart-failure-prone rats. Yi, X.P., Gerdes, A.M., Li, F. Hypertension (2002)
- alpha-actinin-2 in rat striatum: localization and interaction with NMDA glutamate receptor subunits. Dunah, A.W., Wyszynski, M., Martin, D.M., Sheng, M., Standaert, D.G. Brain Res. Mol. Brain Res. (2000)
- The neural cell adhesion molecule is associated with major components of the cytoskeleton. Büttner, B., Kannicht, C., Reutter, W., Horstkorte, R. Biochem. Biophys. Res. Commun. (2003)
- Regulation of the L-type calcium channel by alpha 5beta 1 integrin requires signaling between focal adhesion proteins. Wu, X., Davis, G.E., Meininger, G.A., Wilson, E., Davis, M.J. J. Biol. Chem. (2001)
- Regulation of single NMDA receptor channel activity by alpha-actinin and calmodulin in rat hippocampal granule cells. Rycroft, B.K., Gibb, A.J. J. Physiol. (Lond.) (2004)
- Effects of profilin and profilactin on actin structure and function in living cells. Cao, L.G., Babcock, G.G., Rubenstein, P.A., Wang, Y.L. J. Cell Biol. (1992)
- Can grafted cardiomyocytes colonize peri-infarct myocardial areas? Scorsin, M., Marotte, F., Sabri, A., Le Dref, O., Demirag, M., Samuel, J.L., Rappaport, L., Menasché, P. Circulation (1996)
- Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virus. David-Pfeuty, T., Singer, S.J. Proc. Natl. Acad. Sci. U.S.A. (1980)
- Ultrastructural organization of contractile proteins in rat glomerular mesangial cells. Drenckhahn, D., Schnittler, H., Nobiling, R., Kriz, W. Am. J. Pathol. (1990)
- Cell-to-substratum contacts in living cells: a direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and alpha-actinin. Wehland, J., Osborn, M., Weber, K. J. Cell. Sci. (1979)