Gene Review:
DACH1 - dachshund family transcription factor 1
Homo sapiens
Synonyms:
DACH, Dach1, Dachshund homolog 1
- DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. Wu, K., Yang, Y., Wang, C., Davoli, M.A., D'Amico, M., Li, A., Cveklova, K., Kozmik, Z., Lisanti, M.P., Russell, R.G., Cvekl, A., Pestell, R.G. J. Biol. Chem. (2003)
- Expression Profiling Identifies Altered Expression of Genes That Contribute to the Inhibition of Transforming Growth Factor-{beta} Signaling in Ovarian Cancer. Sunde, J.S., Donninger, H., Wu, K., Johnson, M.E., Pestell, R.G., Rose, G.S., Mok, S.C., Brady, J., Bonome, T., Birrer, M.J. Cancer Res. (2006)
- Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene. Kozmik, Z., Pfeffer, P., Kralova, J., Paces, J., Paces, V., Kalousova, A., Cvekl, A. Dev. Genes Evol. (1999)
- A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer. Dragovich, T., Mendelson, D., Kurtin, S., Richardson, K., Von Hoff, D., Hoos, A. Cancer Chemother. Pharmacol. (2006)
- Impaired interactions between mouse Eyal harboring mutations found in patients with branchio-oto-renal syndrome and Six, Dach, and G proteins. Ozaki, H., Watanabe, Y., Ikeda, K., Kawakami, K. J. Hum. Genet. (2002)
- DACH1 Is a Cell Fate Determination Factor That Inhibits Cyclin D1 and Breast Tumor Growth. Wu, K., Li, A., Rao, M., Liu, M., Dailey, V., Yang, Y., Di Vizio, D., Wang, C., Lisanti, M.P., Sauter, G., Russell, R.G., Cvekl, A., Pestell, R.G. Mol. Cell. Biol. (2006)
- Mutations in the transcriptional activator EYA4 cause late-onset deafness at the DFNA10 locus. Wayne, S., Robertson, N.G., DeClau, F., Chen, N., Verhoeven, K., Prasad, S., Tranebjärg, L., Morton, C.C., Ryan, A.F., Van Camp, G., Smith, R.J. Hum. Mol. Genet. (2001)
- Biochemical pharmacology of homologous alicyclic mixed amine platinum(II) complexes in sensitive and resistant tumor cell lines. Yoshida, M., Khokhar, A.R., Siddik, Z.H. Cancer Res. (1994)
- Localization of the human homologue of the Drosophila dachshund gene (DACH) to chromosome 13q21. Kozmik, Z., Cvekl, A. Genomics (1999)
- DACH: genomic characterization, evaluation as a candidate for postaxial polydactyly type A2, and developmental expression pattern of the mouse homologue. Ayres, J.A., Shum, L., Akarsu, A.N., Dashner, R., Takahashi, K., Ikura, T., Slavkin, H.C., Nuckolls, G.H. Genomics (2001)
- Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups. Kraker, A.J., Hoeschele, J.D., Elliott, W.L., Showalter, H.D., Sercel, A.D., Farrell, N.P. J. Med. Chem. (1992)
- DNA sequence selectivity of cisplatin analogues in intact human cells. Murray, V., Whittaker, J., McFadyen, W.D. Chem. Biol. Interact. (1998)
- Application of capillary electrophoresis-mass spectrometry for the investigation of the binding behavior of oxaliplatin to 5'-GMP in the presence of the sulfur-containing amino acid L-methionine. Strickmann, D.B., Kong, A., Keppler, B.K. Electrophoresis (2002)
- Rotamer stability in cis-[Pt(diA)G2] complexes (diA = diamine derivative and G = guanine derivative) mediated by carrier-ligand amine stereochemistry as revealed by circular dichroism spectroscopy. Benedetti, M., Marzilli, L.G., Natile, G. Chemistry (Weinheim an der Bergstrasse, Germany) (2005)
- Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin. Donahue, B.A., Augot, M., Bellon, S.F., Treiber, D.K., Toney, J.H., Lippard, S.J., Essigmann, J.M. Biochemistry (1990)
- Chemistry of ruthenium(II) monohydride and dihydride complexes containing pyridyl donor ligands including catalytic ketone H2-hydrogenation. Abdur-Rashid, K., Abbel, R., Hadzovic, A., Lough, A.J., Morris, R.H. Inorganic chemistry. (2005)