Gene Review:
Kcnd2 - potassium voltage-gated channel, Shal...
Mus musculus
Synonyms:
AI839615, AW555701, Kiaa1044, Kv4.2, MNCb-7013, ...
- Targeted deletion of Kv4.2 eliminates I(to,f) and results in electrical and molecular remodeling, with no evidence of ventricular hypertrophy or myocardial dysfunction. Guo, W., Jung, W.E., Marionneau, C., Aimond, F., Xu, H., Yamada, K.A., Schwarz, T.L., Demolombe, S., Nerbonne, J.M. Circ. Res. (2005)
- A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Kuo, H.C., Cheng, C.F., Clark, R.B., Lin, J.J., Lin, J.L., Hoshijima, M., Nguyêñ-Trân, V.T., Gu, Y., Ikeda, Y., Chu, P.H., Ross, J., Giles, W.R., Chien, K.R. Cell (2001)
- A secretory-type protein, containing a pentraxin domain, interacts with an A-type K+ channel. Duzhyy, D., Harvey, M., Sokolowski, B. J. Biol. Chem. (2005)
- Characterization of mice with a combined suppression of I(to) and I(K,slow). Brunner, M., Guo, W., Mitchell, G.F., Buckett, P.D., Nerbonne, J.M., Koren, G. Am. J. Physiol. Heart Circ. Physiol. (2001)
- The kv4.2 potassium channel subunit is required for pain plasticity. Hu, H.J., Carrasquillo, Y., Karim, F., Jung, W.E., Nerbonne, J.M., Schwarz, T.L., Gereau, R.W. Neuron (2006)
- The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Costantini, D.L., Arruda, E.P., Agarwal, P., Kim, K.H., Zhu, Y., Zhu, W., Lebel, M., Cheng, C.W., Park, C.Y., Pierce, S.A., Guerchicoff, A., Pollevick, G.D., Chan, T.Y., Kabir, M.G., Cheng, S.H., Husain, M., Antzelevitch, C., Srivastava, D., Gross, G.J., Hui, C.C., Backx, P.H., Bruneau, B.G. Cell (2005)
- Role of Topoisomerase II{beta} in the Expression of Developmentally Regulated Genes. Lyu, Y.L., Lin, C.P., Azarova, A.M., Cai, L., Wang, J.C., Liu, L.F. Mol. Cell. Biol. (2006)
- Calcineurin Increases Cardiac Transient Outward K+ Currents via Transcriptional Up-regulation of Kv4.2 Channel Subunits. Gong, N., Bodi, I., Zobel, C., Schwartz, A., Molkentin, J.D., Backx, P.H. J. Biol. Chem. (2006)
- Unanticipated Region- and Cell-Specific Downregulation of Individual KChIP Auxiliary Subunit Isotypes in Kv4.2 Knock-Out Mouse Brain. Menegola, M., Trimmer, J.S. J. Neurosci. (2006)
- Modulation of Kv4.2 channels by a peptide isolated from the venom of the giant bird-eating tarantula Theraphosa leblondi. Ebbinghaus, J., Legros, C., Nolting, A., Guette, C., Celerier, M.L., Pongs, O., Bähring, R. Toxicon (2004)
- Functional knockout of the transient outward current, long-QT syndrome, and cardiac remodeling in mice expressing a dominant-negative Kv4 alpha subunit. Barry, D.M., Xu, H., Schuessler, R.B., Nerbonne, J.M. Circ. Res. (1998)
- Differential Expression of IA Channel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses. Burkhalter, A., Gonchar, Y., Mellor, R.L., Nerbonne, J.M. J. Neurosci. (2006)
- A role for Kif17 in transport of Kv4.2. Chu, P.J., Rivera, J.F., Arnold, D.B. J. Biol. Chem. (2006)
- Electrophysiological and pharmacological correspondence between Kv4.2 current and rat cardiac transient outward current. Yeola, S.W., Snyders, D.J. Cardiovasc. Res. (1997)
- Mossy fibre contact triggers the targeting of Kv4.2 potassium channels to dendrites and synapses in developing cerebellar granule neurons. Shibasaki, K., Nakahira, K., Trimmer, J.S., Shibata, R., Akita, M., Watanabe, S., Ikenaka, K. J. Neurochem. (2004)
- Postsynaptic and extrasynaptic localization of Kv4.2 channels in the mouse hippocampal region, with special reference to targeted clustering at gabaergic synapses. Jinno, S., Jeromin, A., Kosaka, T. Neuroscience (2005)
- Input-specific immunolocalization of differentially phosphorylated Kv4.2 in the mouse brain. Varga, A.W., Anderson, A.E., Adams, J.P., Vogel, H., Sweatt, J.D. Learn. Mem. (2000)
- Pituitary adenylate cyclase activating polypeptide reduces expression of Kv1.4 and Kv4.2 subunits underlying A-type K(+) current in adult mouse olfactory neuroepithelia. Han, P., Lucero, M.T. Neuroscience (2006)
- Role of heteromultimers in the generation of myocardial transient outward K+ currents. Guo, W., Li, H., Aimond, F., Johns, D.C., Rhodes, K.J., Trimmer, J.S., Nerbonne, J.M. Circ. Res. (2002)
- Mouse DREAM/calsenilin/KChIP3: gene structure, coding potential, and expression. Spreafico, F., Barski, J.J., Farina, C., Meyer, M. Mol. Cell. Neurosci. (2001)
- Characterization of the A-type potassium current in murine gastric antrum. Amberg, G.C., Baker, S.A., Koh, S.D., Hatton, W.J., Murray, K.J., Horowitz, B., Sanders, K.M. J. Physiol. (Lond.) (2002)