Disease relevance of NOC2L

• Near-IR (NIR) excitation at liquid He temperatures of photosystem II (PSII) membranes from the cyanobacterium Synechococcus vulcanus or from spinach poised in the S2 state results in the production of a g = 2.035 EPR resonance, reminiscent of metalloradical signals [1].
• Wavelengths longer than the NIR wavelengths, although they could conceivably account for the occurrence of melanoma under clothed parts of the body, carry so little energy that they are probably unimportant [2].
• Successful stent delivery was achieved in 100% versus 98.8%, respectively, with a slightly lower postprocedural diameter stenosis (7% vs. 9%, p = 0.04) after NIR and PS stent placement, respectively [3].
• The study was an "equivalency" trial, designed to demonstrate that the NIR stent was not inferior to (i.e., equivalent or better than) the PS stent, for the primary end point of target vessel failure (defined as death, myocardial infarction, or target vessel revascularization) by 9 months [3].
• Immediate and midterm results of 61 NIR stent placement attempts in 55 native coronary vessels in 52 patients demonstrate a high clinical success rate of 98%, no early stent thrombosis, and a 5-month angiographic restenosis rate of 23% [4].

High impact information on NOC2L

• The IR patients differed from the NIR patients with respect to higher frequency of ICAs (P less than .001), thyroid antibodies (P less than .02), and the HLA antigen DR4 (P less than .02) [5].
• The latter, most importantly, represents the first (dyad) member of a series of p-doped tetrathiafulvalene (stacked) arrays, and the thorough scrutiny of its electronic structure with the aid of Mulliken-Hush (two-state) analysis of the diagnostic (intervalence) NIR band reveals Robin-Day Class II behavior [6].
• The combination of cyclic voltammetry, dynamic ESR line broadening, and electronic (NIR) spectroscopy allows the intervalence electron transfer between the redox centers in the mixed-valence system D-br-D*(+) [where br can be an aliphatic trimethylene or an aromatic (poly)phenylene bridge] to be probed quantitatively [7].
• METHODS: One hundred and twenty patients with lesions in small coronary arteries (de novo, non-ostial lesion and reference diameter <3 mm) were randomly assigned to either balloon angioplasty or elective stent placement (7-cell NIR stent) [8].
• NIR lanthanide luminescence by energy transfer from appended terpyridine-boradiazaindacene dyes [9].

Chemical compound and disease context of NOC2L

• In conclusion, when compared with implantation of an uncoated premounted NIR stent, implantation of a heparin-coated premounted Jostent does not provide any more benefit with respect to initial efficacy, sub(acute) thrombosis and 6-month restenosis rates and 12-month clinical outcomes [10].

Biological context of NOC2L

• Two important sequence elements, designated insulin enhancer binding site 1 (IEB1) or NIR and IEB2 or FAR, are involved in regulating expression of the rat insulin I gene [11].
• The identification is based on the comparison of the NIR spectrum of a sample with typical spectra of the authentic drug using multivariate modelling and classification algorithms (PCA/SIMCA) [12].
• Characterization of hemoglobin, water, and NIR scattering in breast tissue: analysis of intersubject variability and menstrual cycle changes [13].
• We discuss various methodological aspects and state of the art of fiber optic NIR RS in clinical and experimental dermatology to outline its present advantages and disadvantages for measuring skin in vivo, particularly its water content [14].
• Sterile probes for emitting and detecting NIR light at a fixed separation of 40 mm were placed in turn on intact skin, skull, dura and cerebral cortex of 10 patients undergoing elective neurosurgery [15].

Anatomical context of NOC2L

• A comparative evaluation of the effects of four sterilization methods on dentin disks was based on FTIR and ultraviolet-visible-near infrared (UV/VIS/NIR) spectra before and after sterilization by (1) gamma irradiation; (2) ethylene oxide; (3) dry heat; and (4) autoclaving [16].
• NIR spectra of 118 sections from 36 human aortas were measured at 1000-2500 nm [17].
• CONCLUSION: The findings indicate that simple assumptions regarding the distribution of the internal carotid artery blood supply to cerebral and extracerebral tissues, the photon path length through those tissues, and their relative contributions to attenuation of NIR light may not be justified [18].
• Development of a fiber optic probe to measure NIR Raman spectra of cervical tissue in vivo [19].
• Potentially, NIR offers the prospect of real-time control of the physiology of cultured cells in fermenters, leading to marked improvements in authenticity, purity and production efficiency [20].

Associations of NOC2L with chemical compounds

• Specifically, the Au-imidazole assemblies formed at lower imidazole concentrations had the lowest fractal dimension (D(f) = 1.2) and the largest Raman enhancement factors for the dominant NIR-SERS feature, a ring-breathing vibrational mode at 954 cm(-1) [21].
• The self-assembled Au-imidazole complexes were generated by the adsorption of imidazole molecules onto Au nanoparticles (NP) and were then characterized as aqueous suspensions by using NIR-SERS, angle-dependent light scattering with fractal dimension analysis, and visible extinction spectroscopy [21].
• The NIR-induced increase in the oxidative capability of the Mn cluster is discussed in relation to the photochemical properties of a Mn(III) ion that exists in both S2 and S3 states [1].
• Routine NIR analysis of caffeine in tablet form was found to be more flexible and much faster than that performed with the HPLC method [22].
• The formation of the silica network and the titanium insertion were followed by a combination of diffuse reflectance UV/ Vis/NIR and FTIR spectroscopy [23].

Analytical, diagnostic and therapeutic context of NOC2L

• METHODS and RESULTS: We deployed 3.0- and 4.0-mm Palmaz-Schatz, Wiktor, Multilink, NIR, and InStent stents in precision-cast phantoms [24].
• Additional evidence for the strong electronic coupling is provided by UV-vis, NIR, and EPR spectroscopies and DFT calculations [25].
• Quantitative near-IR (NIR) spectroscopic studies of these SWNT graft copolymers indicate a water solubility of about 5 mg/mL, and atomic force microscopy studies show a fairly uniform length and diameter [26].
• A randomized comparison of the value of additional stenting after optimal balloon angioplasty for long coronary lesions: final results of the additional value of NIR stents for treatment of long coronary lesions (ADVANCE) study [27].
• A similar increase was found from pulse radiolysis experiments on the wt NIR and three variants (Met150Gly, Met150His, and Met150Thr) [28].

References