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Gene Review

SSPO  -  SCO-spondin

Bos taurus

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High impact information on SSPO


Biological context of SSPO


Anatomical context of SSPO


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Analytical, diagnostic and therapeutic context of SSPO


  1. The complex multidomain organization of SCO-spondin protein is highly conserved in mammals. Meiniel, O., Meiniel, A. Brain Res. Brain Res. Rev. (2007) [Pubmed]
  2. SCO-spondin and RF-GlyI: two designations for the same glycoprotein secreted by the subcommissural organ. Didier, R., Creveaux, I., Meiniel, R., Herbet, A., Dastugue, B., Meiniel, A. J. Neurosci. Res. (2000) [Pubmed]
  3. Transcription of SCO-spondin in the subcommissural organ: evidence for down-regulation mediated by serotonin. Richter, H.G., Tomé, M.M., Yulis, C.R., Vío, K.J., Jiménez, A.J., Pérez-Fígares, J.M., Rodríguez, E.M. Brain Res. Mol. Brain Res. (2004) [Pubmed]
  4. Reissner fiber binds and transports away monoamines present in the cerebrospinal fluid. Caprile, T., Hein, S., Rodríguez, S., Montecinos, H., Rodríguez, E. Brain Res. Mol. Brain Res. (2003) [Pubmed]
  5. The floor plate cells from bovines express the mRNA encoding for SCO-spondin and its translation products. Richter, H.G., Muñoz, R.I., Millán, C.S., Guiñazú, M.F., Yulis, C.R., Rodríguez, E.M. Brain Res. Mol. Brain Res. (2001) [Pubmed]
  6. SCO-spondin, a glycoprotein of the subcommissural organ/Reissner's fiber complex: evidence of a potent activity on neuronal development in primary cell cultures. Meiniel, A. Microsc. Res. Tech. (2001) [Pubmed]
  7. Complex expression pattern of the SCO-spondin gene in the bovine subcommissural organ: toward an explanation for Reissner's fiber complexity? Creveaux, I., Gobron, S., Meiniel, R., Dastugue, B., Meiniel, A. Brain Res. Mol. Brain Res. (1998) [Pubmed]
  8. Bovine floor plate explants secrete SCO-spondin. Guiñazú, M.F., Richter, H.G., Rodríguez, E.M. Cell Tissue Res. (2002) [Pubmed]
  9. SCO-spondin is evolutionarily conserved in the central nervous system of the chordate phylum. Gobron, S., Creveaux, I., Meiniel, R., Didier, R., Dastugue, B., Meiniel, A. Neuroscience (1999) [Pubmed]
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