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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review


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Disease relevance of Cattle


High impact information on Cattle


Biological context of Cattle


Anatomical context of Cattle


Associations of Cattle with chemical compounds

  • Naturally occurring antibody repertoires of cattle (Bos taurus) include a group of IgMlambda antibodies with exceptionally long complementarity-determining region 3 of the heavy chain (CDR3H) segments, containing multiple Cys residues [21].
  • Changes in pulsatile secretion of LH, FSH, oestradiol and progesterone were related to the growth phase, early plateau phase and regression phase of the first ovarian dominant follicle of the oestrous cycle in Bos indicus heifers [22].
  • Heritable testicular hypoplasia in Nguni (Bos indicus) bulls: vascular characteristics and testosterone production [23].
  • Amplification and sequencing of expressed DRB second exons from Bos indicus [24].
  • Two experiments evaluated a modified delivery of prostaglandin F2alpha (PGF2alpha) after a melengestrol acetate (MGA) treatment in Angus and Bos indicus x Bos taurus (BI) heifers [25].

Gene context of Cattle

  • To gain insight into biologically conserved functional motifs, we isolated an ortholog of BRCA1 from cattle (Bos taurus) [26].
  • Promoter-specific expression of the imprinted IGF2 gene in cattle (Bos taurus) [27].
  • A PRP10 polymorphism, which is apparently the result of a insertion/deletion event, detected polymorphism frequency differences between Bos indicus and Bos taurus [28].
  • Six BoLA class I cDNAs have been cloned and sequenced from a Bos taurus bull heterozygous for BoLA class I serological antigens, demonstrating the presence of a minimum of three loci [29].
  • Additionally, one synonymous and one non-synonymous single nucleotide polymorphism (SNP) were detected in PRKAG3 in Bos taurus cattle [30].

Analytical, diagnostic and therapeutic context of Cattle


  1. Isolation and characterization of the Rickettsia prowazekii gene encoding the flavoprotein subunit of succinate dehydrogenase. Aliabadi, Z., Winkler, H.H., Wood, D.O. Gene (1993) [Pubmed]
  2. A cement protein of the tick Rhipicephalus appendiculatus, located in the secretory e cell granules of the type III salivary gland acini, induces strong antibody responses in cattle. Bishop, R., Lambson, B., Wells, C., Pandit, P., Osaso, J., Nkonge, C., Morzaria, S., Musoke, A., Nene, V. Int. J. Parasitol. (2002) [Pubmed]
  3. Immune responses of trypanoresistant and trypanosusceptible cattle after cyclic infection with Trypanosoma congolense. Pinder, M., Bauer, J., Van Melick, A., Fumoux, F. Vet. Immunol. Immunopathol. (1988) [Pubmed]
  4. Excess cortisol interferes with a principal mechanism of resistance to dehydration in Bos indicus steers. Parker, A.J., Hamlin, G.P., Coleman, C.J., Fitzpatrick, L.A. J. Anim. Sci. (2004) [Pubmed]
  5. Long-term occurrence of Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia. Mulugeta, W., Wilkes, J., Mulatu, W., Majiwa, P.A., Masake, R., Peregrine, A.S. Acta Trop. (1997) [Pubmed]
  6. Gene-culture coevolution between cattle milk protein genes and human lactase genes. Beja-Pereira, A., Luikart, G., England, P.R., Bradley, D.G., Jann, O.C., Bertorelle, G., Chamberlain, A.T., Nunes, T.P., Metodiev, S., Ferrand, N., Erhardt, G. Nat. Genet. (2003) [Pubmed]
  7. Myxococcus xanthus, a gram-negative bacterium, contains a transmembrane protein serine/threonine kinase that blocks the secretion of beta-lactamase by phosphorylation. Udo, H., Munoz-Dorado, J., Inouye, M., Inouye, S. Genes Dev. (1995) [Pubmed]
  8. Dual-mode recognition of noncanonical tRNAs(Ser) by seryl-tRNA synthetase in mammalian mitochondria. Chimnaronk, S., Gravers Jeppesen, M., Suzuki, T., Nyborg, J., Watanabe, K. EMBO J. (2005) [Pubmed]
  9. Evidence for two independent domestications of cattle. Loftus, R.T., MacHugh, D.E., Bradley, D.G., Sharp, P.M., Cunningham, P. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  10. Molecular cloning of a prolactin-related mRNA expressed in bovine placenta. Schuler, L.A., Hurley, W.L. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  11. The cleavage and polyadenylation specificity factor in Xenopus laevis oocytes is a cytoplasmic factor involved in regulated polyadenylation. Dickson, K.S., Bilger, A., Ballantyne, S., Wickens, M.P. Mol. Cell. Biol. (1999) [Pubmed]
  12. Expression of new members of the prolactin growth hormone gene family in bovine placenta. Isolation and characterization of two prolactin-like cDNA clones. Yamakawa, M., Tanaka, M., Koyama, M., Kagesato, Y., Watahiki, M., Yamamoto, M., Nakashima, K. J. Biol. Chem. (1990) [Pubmed]
  13. Comparative pharmacokinetics of diminazene in noninfected Boran (Bos indicus) cattle and Boran cattle infected with Trypanosoma congolense. Mamman, M., Aliu, Y.O., Peregrine, A.S. Antimicrob. Agents Chemother. (1993) [Pubmed]
  14. Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus). MacHugh, D.E., Shriver, M.D., Loftus, R.T., Cunningham, P., Bradley, D.G. Genetics (1997) [Pubmed]
  15. Evolution of NK receptors: a single Ly49 and multiple KIR genes in the cow. McQueen, K.L., Wilhelm, B.T., Harden, K.D., Mager, D.L. Eur. J. Immunol. (2002) [Pubmed]
  16. Heterologous in vitro fertilization and sperm capacitation in an endangered African antelope, the scimitar-horned oryx (Oryx dammah). Roth, T.L., Weiss, R.B., Buff, J.L., Bush, L.M., Wildt, D.E., Bush, M. Biol. Reprod. (1998) [Pubmed]
  17. Trypanosoma congolense infection of trypanotolerant N'Dama (Bos taurus) cattle is associated with decreased secretion of nitric oxide by interferon-gamma-activated monocytes and increased transcription of interleukin-10. Taylor, K., Mertens, B., Lutje, V., Saya, R. Parasite Immunol. (1998) [Pubmed]
  18. Erythrocyte surface sialic acid in Ndama and Zebu cattle. Esievo, K.A., Saror, D.I., Kolo, M.N., Eduvie, L.O. J. Comp. Pathol. (1986) [Pubmed]
  19. Immunocytochemical localization of the catecholamine-synthesizing enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase, in the hypothalamus of cattle. Leshin, L.S., Kraeling, R.R., Kiser, T.E. J. Chem. Neuroanat. (1995) [Pubmed]
  20. Effects of dietary clenbuterol on net flux across the portal-drained viscera, liver and hindquarters of steers (Bos taurus). Eisemann, J.H., Huntington, G.B. Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. (1993) [Pubmed]
  21. Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings. Saini, S.S., Farrugia, W., Ramsland, P.A., Kaushik, A.K. Int. Immunol. (2003) [Pubmed]
  22. Hormone concentrations in the caudal vena cava during the first ovarian follicular wave of the oestrous cycle in heifers. Rhodes, F.M., Fitzpatrick, L.A., Entwistle, K.W., Kinder, J.E. J. Reprod. Fertil. (1995) [Pubmed]
  23. Heritable testicular hypoplasia in Nguni (Bos indicus) bulls: vascular characteristics and testosterone production. Kay, G.W., Grobbelaar, J.A., Hattingh, J. J. Reprod. Fertil. (1992) [Pubmed]
  24. Amplification and sequencing of expressed DRB second exons from Bos indicus. Russell, G.C., Marello, K.L., Gallagher, A., McKeever, D.J., Spooner, R.L. Immunogenetics (1994) [Pubmed]
  25. Efficacy of either a single or split treatment of PGF2alpha after a 14 day melengestrol acetate treatment to synchronize estrus and induce luteolysis in Bos indicus x Bos taurus heifers. Bridges, G.A., Portillo, G.E., de Araujo, J.W., Thatcher, W.W., Yelich, J.V. Theriogenology (2005) [Pubmed]
  26. Bovine BRCA1 shows classic responses to genotoxic stress but low in vitro transcriptional activation activity. Krum, S.A., Womack, J.E., Lane, T.F. Oncogene (2003) [Pubmed]
  27. Promoter-specific expression of the imprinted IGF2 gene in cattle (Bos taurus). Curchoe, C., Zhang, S., Bin, Y., Zhang, X., Yang, L., Feng, D., O'Neill, M., Tian, X.C. Biol. Reprod. (2005) [Pubmed]
  28. Somatic cell mapping, polymorphism, and linkage analysis of bovine prolactin-related proteins and placental lactogen. Dietz, A.B., Georges, M., Threadgill, D.W., Womack, J.E., Schuler, L.A. Genomics (1992) [Pubmed]
  29. Evidence for at least three transcribed BoLA class I loci. Garber, T.L., Hughes, A.L., Watkins, D.I., Templeton, J.W. Immunogenetics (1994) [Pubmed]
  30. The bovine 5' AMPK gene family: mapping and single nucleotide polymorphism detection. McKay, S.D., White, S.N., Kata, S.R., Loan, R., Womack, J.E. Mamm. Genome (2003) [Pubmed]
  31. Synchronization of Bos indicus x Bos taurus cows for timed artificial insemination using gonadotropin-releasing hormone plus prostaglandin F2alpha in combination with melengestrol acetate. Hiers, E.A., Barthle, C.R., Dahms, M.K., Portillo, G.E., Bridges, G.A., Rae, D.O., Thatcher, W.W., Yelich, J.V. J. Anim. Sci. (2003) [Pubmed]
  32. Effects of electrical stimulation and postmortem storage on changes in titin, nebulin, desmin, troponin-T, and muscle ultrastructure in Bos indicus crossbred cattle. Ho, C.Y., Stromer, M.H., Rouse, G., Robson, R.M. J. Anim. Sci. (1997) [Pubmed]
  33. Influence of suckling and continuous cow-calf association on the resumption of post-partum ovarian function in Bos indicus cows monitored by plasma progesterone profiles. Mukasa-Mugerwa, E., Tegegne, A., Franceschini, R. Reprod. Nutr. Dev. (1991) [Pubmed]
  34. Ultrasonographic screening of embryo development in cattle (Bos indicus) between days 20 and 40 of pregnancy. Rosiles, V.A., Galina, C.S., Maquivar, M., Molina, R., Estrada, S. Anim. Reprod. Sci. (2005) [Pubmed]
  35. Recombinant Jembrana disease virus proteins as antigens for the detection of antibody to bovine lentiviruses. Burkala, E.J., Narayani, I., Hartaningsih, N., Kertayadnya, G., Berryman, D.I., Wilcox, G.E. J. Virol. Methods (1998) [Pubmed]
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