Disease relevance of Cattle

• The deduced aa sequence, when compared to the flavoprotein subunits of Escherichia coli, Bacillus subtilis, Saccharomyces cerevisiae and Bos taurus, revealed 52.8, 34.0, 65.8 and 52.0% aa identity, respectively [1].
• An Escherichia coli recombinant form of the proline-rich C-terminal domain of RIM36 reacts with antisera from Bos indicus cattle, either experimentally infested with R. appendiculatus, or exposed to ticks in the field [2].
• To study the mechanisms by which certain West African taurine cattle are able to resist trypanosomiasis, the disease course and several immune parameters were examined in eleven Baoulé and five Zebu cattle after infection with tsetse-transmitted T. congolense (clone 1180 of stock Serengeti/71/STIB/212) [3].
• Excess cortisol interferes with a principal mechanism of resistance to dehydration in Bos indicus steers [4].
• When inoculated into naïve Boran (Bos indicus) calves, all 10 isolates were resistant to diminazene aceturate (Berenil), isometamidium chloride (Samorin) and homidium chloride (Novidium) at doses of 7.0 mg/kg body weight (b.w.), 0.5 mg/kg b.w. and 1.0 mg/kg b.w., respectively [5].

High impact information on Cattle

• Milk from domestic cows has been a valuable food source for over 8,000 years, especially in lactose-tolerant human societies that exploit dairy breeds [6].
• The catalytic domain of Pkn2 contains 27% and 25% identity to rat Ca2+/calmodulin-dependent protein kinase and Bos taurus rhodopsin kinase, respectively [7].
• Here, we report the crystal structure of mammalian mt SerRS from Bos taurus in complex with seryl adenylate at an atomic resolution of 1.65 A [8].
• Zebu and taurine breeds are differentiated primarily by the presence or absence of a hump and have been recognized as separate species (Bos indicus and Bos taurus) [9].
• Bovine (Bos taurus) prolactin-related cDNA I (bPRC-I), distinct from the isolated bovine placental lactogen, was derived from bovine fetal placental mRNA by molecular cloning [10].

Biological context of Cattle

• The protein product is 91% identical at the amino acid sequence level to nuclear CPSF isolated from Bos taurus thymus [11].
• Two prolactin-like proteins (bPLP-I and bPLP-II) were deduced from the nucleotide sequence analyses of the cDNA clones derived from a bovine (Bos taurus) term placenta [12].
• Comparative pharmacokinetics of diminazene in noninfected Boran (Bos indicus) cattle and Boran cattle infected with Trypanosoma congolense [13].
• Microsatellite DNA variation and the evolution, domestication and phylogeography of taurine and zebu cattle (Bos taurus and Bos indicus) [14].
• By screening a bovine spleen cDNA library, we isolated an Ly49 gene from the cow (Bos Taurus) and show by genomic Southern blotting that it is likely a single copy gene in this species [15].

Anatomical context of Cattle

• Objectives were to assess sperm 1) viability and motility in vitro over time, 2) capacitation in heparin- or calcium-supplemented medium, and 3) function in an in vitro fertilization system using heterologous (domestic cow) oocytes [16].
• Trypanosoma congolense infection of trypanotolerant N'Dama (Bos taurus) cattle is associated with decreased secretion of nitric oxide by interferon-gamma-activated monocytes and increased transcription of interleukin-10 [17].
• Ndama adults and calves had significantly (P less than 0.001) higher erythrocyte surface sialic acid concentrations than Zebu adults [18].
• Immunocytochemical staining for the presence of catecholamine synthesizing enzymes, tyrosine hydroxylase and dopamine beta-hydroxylase, was used to characterize the regional distribution of catecholaminergic neurons in the hypothalamus and adjacent areas of domestic cattle, Bos taurus [19].
• Effects of dietary clenbuterol on net flux across the portal-drained viscera, liver and hindquarters of steers (Bos taurus) [20].

Associations of Cattle with chemical compounds

• Naturally occurring antibody repertoires of cattle (Bos taurus) include a group of IgMlambda antibodies with exceptionally long complementarity-determining region 3 of the heavy chain (CDR3H) segments, containing multiple Cys residues [21].
• Changes in pulsatile secretion of LH, FSH, oestradiol and progesterone were related to the growth phase, early plateau phase and regression phase of the first ovarian dominant follicle of the oestrous cycle in Bos indicus heifers [22].
• Heritable testicular hypoplasia in Nguni (Bos indicus) bulls: vascular characteristics and testosterone production [23].
• Amplification and sequencing of expressed DRB second exons from Bos indicus [24].
• Two experiments evaluated a modified delivery of prostaglandin F2alpha (PGF2alpha) after a melengestrol acetate (MGA) treatment in Angus and Bos indicus x Bos taurus (BI) heifers [25].

Gene context of Cattle

• To gain insight into biologically conserved functional motifs, we isolated an ortholog of BRCA1 from cattle (Bos taurus) [26].
• Promoter-specific expression of the imprinted IGF2 gene in cattle (Bos taurus) [27].
• A PRP10 polymorphism, which is apparently the result of a insertion/deletion event, detected polymorphism frequency differences between Bos indicus and Bos taurus [28].
• Six BoLA class I cDNAs have been cloned and sequenced from a Bos taurus bull heterozygous for BoLA class I serological antigens, demonstrating the presence of a minimum of three loci [29].
• Additionally, one synonymous and one non-synonymous single nucleotide polymorphism (SNP) were detected in PRKAG3 in Bos taurus cattle [30].

Analytical, diagnostic and therapeutic context of Cattle

• Nonlactating Bos indicus x Bos taurus cows were used in three herds to determine the efficacy of different PGF2alpha treatments in combination with GnRH and melengestrol acetate (MGA) for a timed artificial insemination protocol [31].
• Effects of electrical stimulation and postmortem storage on changes in titin, nebulin, desmin, troponin-T, and muscle ultrastructure in Bos indicus crossbred cattle [32].
• The effect of suckling on post-partum ovarian function was monitored by weekly plasma progesterone determinations using enzyme immunoassay in 16 Small East African Zebu (Bos indicus) cows maintained with a fertile bull [33].
• Through a transrectal ultrasonography (Aloka SSD 500 microplus equipment, linear transducer of 7.5 MHz) a total of 267 observations were performed in a group of 50 females mainly Bos indicus, raised under humid tropical conditions and pregnant from day 20 every other day until day 40 post-artificial insemination (AI) [34].
• The soluble recombinant CA and TM antigens of JDV were reacted in western immunoblots with both serum antibodies from JDV-infected Bos javanicus cattle and Bos taurus cattle immunized with BIV [35].

References