Gene Review:
Gsn - gelsolin
Rattus norvegicus
Synonyms:
ADF, Actin-depolymerizing factor, Brevin, Gelsolin
- Unphosphorylated gelsolin is localized in regions of cell-substratum contact or attachment in Rous sarcoma virus-transformed rat cells. Wang, E., Yin, H.L., Krueger, J.G., Caliguiri, L.A., Tamm, I. J. Cell Biol. (1984)
- Cells of the neuronal lineage play a major role in the generation of amyloid precursor fragments in gelsolin-related amyloidosis. Paunio, T., Kangas, H., Heinonen, O., Buc-Caron, M.H., Robert, J.J., Kaasinen, S., Julkunen, I., Mallet, J., Peltonen, L. J. Biol. Chem. (1998)
- Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury. Springer, J.E., Azbill, R.D., Knapp, P.E. Nat. Med. (1999)
- Plectin sidearms mediate interaction of intermediate filaments with microtubules and other components of the cytoskeleton. Svitkina, T.M., Verkhovsky, A.B., Borisy, G.G. J. Cell Biol. (1996)
- Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells. Muallem, S., Kwiatkowska, K., Xu, X., Yin, H.L. J. Cell Biol. (1995)
- Evidence for a direct, nucleotide-sensitive interaction between actin and liver cell membranes. Tranter, M.P., Sugrue, S.P., Schwartz, M.A. J. Cell Biol. (1989)
- Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. Beaulieu, V., Da Silva, N., Pastor-Soler, N., Brown, C.R., Smith, P.J., Brown, D., Breton, S. J. Biol. Chem. (2005)
- Gelsolin--evidence for a role in turnover of junction-related actin filaments in Sertoli cells. Guttman, J.A., Janmey, P., Vogl, A.W. J. Cell. Sci. (2002)
- Aging-associated increase of gelsolin for apoptosis resistance. Ahn, J.S., Jang, I.S., Kim, D.I., Cho, K.A., Park, Y.H., Kim, K., Kwak, C.S., Chul Park, S. Biochem. Biophys. Res. Commun. (2003)
- Gelsolin binding and cellular presentation of lysophosphatidic acid. Goetzl, E.J., Lee, H., Azuma, T., Stossel, T.P., Turck, C.W., Karliner, J.S. J. Biol. Chem. (2000)
- Differential modulation of actin-severing activity of gelsolin by multiple isoforms of cultured rat cell tropomyosin. Potentiation of protective ability of tropomyosins by 83-kDa nonmuscle caldesmon. Ishikawa, R., Yamashiro, S., Matsumura, F. J. Biol. Chem. (1989)
- Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex. Hayashi, K., Ishikawa, R., Ye, L.H., He, X.L., Takata, K., Kohama, K., Shirao, T. J. Neurosci. (1996)
- Polymerization of actin in RBL-2H3 cells can be triggered through either the IgE receptor or the adenosine receptor but different signaling pathways are used. Apgar, J.R. Mol. Biol. Cell (1994)
- Gelsolin inhibits apoptosis by blocking mitochondrial membrane potential loss and cytochrome c release. Koya, R.C., Fujita, H., Shimizu, S., Ohtsu, M., Takimoto, M., Tsujimoto, Y., Kuzumaki, N. J. Biol. Chem. (2000)
- The N-terminal Ac-EEED sequence plays a role in alpha-smooth-muscle actin incorporation into stress fibers. Clément, S., Hinz, B., Dugina, V., Gabbiani, G., Chaponnier, C. J. Cell. Sci. (2005)
- Localization and characterization of gelsolin in nervous tissues: gelsolin is specifically enriched in myelin-forming cells. Tanaka, J., Sobue, K. J. Neurosci. (1994)
- Circulating actin-gelsolin complexes following oleic acid-induced lung injury. Smith, D.B., Janmey, P.A., Lind, S.E. Am. J. Pathol. (1988)
- Dynein and plus-end microtubule-dependent motors are associated with specialized Sertoli cell junction plaques (ectoplasmic specializations). Guttman, J.A., Kimel, G.H., Vogl, A.W. J. Cell. Sci. (2000)
- Inhibition of histone deacetylation protects wild-type but not gelsolin-deficient neurons from oxygen/glucose deprivation. Meisel, A., Harms, C., Yildirim, F., Bösel, J., Kronenberg, G., Harms, U., Fink, K.B., Endres, M. J. Neurochem. (2006)