Gene Review:
inaC - inactivation no afterpotential C
Drosophila melanogaster
Synonyms:
CG6518, Dmel\CG6518, Dpkc2, Eye-PKC, INAC, ...
- Photoreceptor deactivation and retinal degeneration mediated by a photoreceptor-specific protein kinase C. Smith, D.P., Ranganathan, R., Hardy, R.W., Marx, J., Tsuchida, T., Zuker, C.S. Science (1991)
- Protein kinase C is required for light adaptation in Drosophila photoreceptors. Hardie, R.C., Peretz, A., Suss-Toby, E., Rom-Glas, A., Bishop, S.A., Selinger, Z., Minke, B. Nature (1993)
- Cytosolic calcium transients: spatial localization and role in Drosophila photoreceptor cell function. Ranganathan, R., Bacskai, B.J., Tsien, R.Y., Zuker, C.S. Neuron (1994)
- Phosphorylation of the InaD gene product, a photoreceptor membrane protein required for recovery of visual excitation. Huber, A., Sander, P., Paulsen, R. J. Biol. Chem. (1996)
- A Drosophila mutant defective in extracellular calcium-dependent photoreceptor deactivation and rapid desensitization. Ranganathan, R., Harris, G.L., Stevens, C.F., Zuker, C.S. Nature (1991)
- Calcium homeostasis in photoreceptor cells of Drosophila mutants inaC and trp studied with the pupil mechanism. Hofstee, C.A., Stavenga, D.G. Vis. Neurosci. (1996)
- Interaction of eye protein kinase C and INAD in Drosophila. Localization of binding domains and electrophysiological characterization of a loss of association in transgenic flies. Adamski, F.M., Zhu, M.Y., Bahiraei, F., Shieh, B.H. J. Biol. Chem. (1998)
- The TRP Ca2+ channel assembled in a signaling complex by the PDZ domain protein INAD is phosphorylated through the interaction with protein kinase C (ePKC). Huber, A., Sander, P., Bähner, M., Paulsen, R. FEBS Lett. (1998)
- Isolation of genes encoding photoreceptor-specific proteins by immunoscreening with antibodies directed against purified blowfly rhabdoms. Huber, A., Sander, P., Wolfrum, U., Groell, C., Gerdon, G., Paulsen, R. J. Photochem. Photobiol. B, Biol. (1996)
- Ca2+ Signaling, TRP Channels, and Endothelial Permeability. Tiruppathi, C., Ahmmed, G.U., Vogel, S.M., Malik, A.B. Microcirculation (New York, N.Y. : 1994) (2006)
- Phosphorylation of Munc-18/n-Sec1/rbSec1 by protein kinase C: its implication in regulating the interaction of Munc-18/n-Sec1/rbSec1 with syntaxin. Fujita, Y., Sasaki, T., Fukui, K., Kotani, H., Kimura, T., Hata, Y., Südhof, T.C., Scheller, R.H., Takai, Y. J. Biol. Chem. (1996)
- Identification and characterization of two distinct calmodulin-binding sites in the Trpl ion-channel protein of Drosophila melanogaster. Warr, C.G., Kelly, L.E. Biochem. J. (1996)
- The second PDZ domain of INAD is a type I domain involved in binding to eye protein kinase C. Mutational analysis and naturally occurring variants. Kumar, R., Shieh, B.H. J. Biol. Chem. (2001)
- Scaffolding protein INAD regulates deactivation of vision by promoting phosphorylation of transient receptor potential by eye protein kinase C in Drosophila. Popescu, D.C., Ham, A.J., Shieh, B.H. J. Neurosci. (2006)
- Direct activation of trpl cation channels by G alpha11 subunits. Obukhov, A.G., Harteneck, C., Zobel, A., Harhammer, R., Kalkbrenner, F., Leopoldt, D., Lückhoff, A., Nürnberg, B., Schultz, G. EMBO J. (1996)
- Reversible phosphorylation of the signal transduction complex in Drosophila photoreceptors. Liu, M., Parker, L.L., Wadzinski, B.E., Shieh, B.H. J. Biol. Chem. (2000)
- Protein kinase C (PKC) isoforms in Drosophila. Shieh, B.H., Parker, L., Popescu, D. J. Biochem. (2002)
- Regulation of Drosophila TRPC channels by protein and lipid interactions. Raghu, P. Semin. Cell Dev. Biol. (2006)
- DWnt4 regulates cell movement and focal adhesion kinase during Drosophila ovarian morphogenesis. Cohen, E.D., Mariol, M.C., Wallace, R.M., Weyers, J., Kamberov, Y.G., Pradel, J., Wilder, E.L. Dev. Cell (2002)
- The tpa-1 gene of Caenorhabditis elegans encodes two proteins similar to Ca(2+)-independent protein kinase Cs: evidence by complete genomic and complementary DNA sequences of the tpa-1 gene. Sano, T., Tabuse, Y., Nishiwaki, K., Miwa, J. J. Mol. Biol. (1995)
- Animal models in the study of protein kinase C isozymes. Choi, D.S., Messing, R.O. Methods Mol. Biol. (2003)