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Gene Review

RARB  -  retinoic acid receptor, beta

Gallus gallus

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Disease relevance of RARB


High impact information on RARB


Chemical compound and disease context of RARB

  • The v-erbA protein, which is the viral oncogenic homologue of the thyroid hormone receptor, was replaced by either the complete RAR beta (beta R) or a hepatitis B virus pre-S-RAR beta (H beta R) hybrid product in an avian erythroblastosis virus-based vector [1].

Biological context of RARB


Anatomical context of RARB


Other interactions of RARB

  • These are the RAR-alpha, RAR-beta and RAR-gamma genes and the RXR-alpha, RXR-beta and RXR-gamma genes [11].

Analytical, diagnostic and therapeutic context of RARB


  1. A hepatitis B virus pre-S-retinoic acid receptor beta chimera transforms erythrocytic progenitor cells in vitro. Garcia, M., de Thé, H., Tiollais, P., Samarut, J., Dejean, A. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
  2. Retinoic acid and mouse skin morphogenesis. II. Role of epidermal competence in hair glandular metaplasia. Viallet, J.P., Dhouailly, D. Dev. Biol. (1994) [Pubmed]
  3. Retinoic acid increases in the retina of the chick with form deprivation myopia. Seko, Y., Shimizu, M., Tokoro, T. Ophthalmic Res. (1998) [Pubmed]
  4. Cell-type-specific regulation of the retinoic acid receptor mediated by the orphan nuclear receptor TLX. Kobayashi, M., Yu, R.T., Yasuda, K., Umesono, K. Mol. Cell. Biol. (2000) [Pubmed]
  5. Development of the spatial pattern of retinoic acid receptor-beta transcripts in embryonic chick facial primordia. Rowe, A., Richman, J.M., Brickell, P.M. Development (1992) [Pubmed]
  6. Retinoic acid treatment alters the distribution of retinoic acid receptor-beta transcripts in the embryonic chick face. Rowe, A., Richman, J.M., Brickell, P.M. Development (1991) [Pubmed]
  7. Temporal and regional differences in the expression pattern of distinct retinoic acid receptor-beta transcripts in the chick embryo. Smith, S.M., Eichele, G. Development (1991) [Pubmed]
  8. Identification of sequence tagged sites in the Asian and African elephant. Burk, N.E., Messer, L.A., Ernst, C.W., Rothschild, M.F. Anim. Biotechnol. (1998) [Pubmed]
  9. Differential expression of retinoic acid receptor-beta isoforms during chick limb ontogeny. Smith, S.M., Kirstein, I.J., Wang, Z.S., Fallon, J.F., Kelley, J., Bradshaw-Rouse, J. Dev. Dyn. (1995) [Pubmed]
  10. Role of the different RAR isoforms in controlling the erythrocytic differentiation sequence. Interference with the v-erbA and p135gag-myb-ets nuclear oncogenes. Gandrillon, O., Samarut, J. Oncogene (1998) [Pubmed]
  11. The chicken retinoid-X-receptor-gamma gene gives rise to two distinct species of mRNA with different patterns of expression. Seleiro, E.A., Darling, D., Brickell, P.M. Biochem. J. (1994) [Pubmed]
  12. All-trans retinoic acid stimulates and maintains neurite outgrowth in nerve growth factor-supported developing chick embryonic sympathetic neurons. Plum, L.A., Clagett-Dame, M. Dev. Dyn. (1996) [Pubmed]
  13. Isolation, partial purification and characterization of nuclear retinoic acid receptors from chick skin. Sani, B.P., Singh, R.K., Reddy, L.G., Gaub, M.P. Arch. Biochem. Biophys. (1990) [Pubmed]
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