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GRIN1  -  glutamate receptor, ionotropic, N-methyl D...

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  • There was no cross-tolerance between kappa and mu opioid receptor agonists as measured with the in vitro electrophysiological assay, and the noncompetitive N-methyl-D-aspartate receptor antagonist MK801 did not prevent the development of tolerance to either the electrophysiological effects or the hypothermic effects of kappa opioids [21].


  1. Mg2+-dependent modification of the N-methyl-D-aspartate receptor following graded hypoxia in the cerebral cortex of newborn piglets. Fritz, K.I., Mishra, O.P., Delivoria-Papadopoulos, M. Neuroscience (1999) [Pubmed]
  2. Dextrorphan inhibits the release of excitatory amino acids during spinal cord ischemia. Rokkas, C.K., Helfrich, L.R., Lobner, D.C., Choi, D.W., Kouchoukos, N.T. Ann. Thorac. Surg. (1994) [Pubmed]
  3. Effects of MK-801 (dizocilpine) on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet. Ko, S.Y., Shim, J.W., Kim, S.S., Kim, M.J., Chang, Y.S., Park, W.S., Shin, S.M., Lee, M.H. J. Korean Med. Sci. (2003) [Pubmed]
  4. Postsynaptic Hebbian and non-Hebbian long-term potentiation of synaptic efficacy in the entorhinal cortex in slices and in the isolated adult guinea pig brain. Alonso, A., de Curtis, M., Llinás, R. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  5. A novel photoaffinity ligand for the phencyclidine site of the N-methyl-D-aspartate receptor labels a Mr 120,000 polypeptide. Sonders, M.S., Barmettler, P., Lee, J.A., Kitahara, Y., Keana, J.F., Weber, E. J. Biol. Chem. (1990) [Pubmed]
  6. Excitatory amino acid-induced phosphoinositide turnover in guinea pig cerebral cortical slices: selective enhancement by spermine of the response to DL-1-aminocyclopentane-trans-1,3-dicarboxylate. Alexander, S.P., Kendall, D.A., Hill, S.J. J. Neurochem. (1992) [Pubmed]
  7. N-methyl-D-aspartate receptor activation and Ca2+ account for poor pyramidal cell structure in hippocampal slices. Feig, S., Lipton, P. J. Neurochem. (1990) [Pubmed]
  8. N-methyl-D-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress. Sharp, C.D., Houghton, J., Elrod, J.W., Warren, A., Jackson, T.H., Jawahar, A., Nanda, A., Minagar, A., Alexander, J.S. Am. J. Physiol. Heart Circ. Physiol. (2005) [Pubmed]
  9. Modification of the glycine (co-activator) binding site of the N-methyl-D-aspartate receptor in the guinea pig fetus brain during development following hypoxia. Razdan, B., Kubin, J., Mishra, O.P., Delivoria-Papadopoulos, M. Brain Res. (1996) [Pubmed]
  10. Spermine dependent activation of the N-methyl-D-aspartate receptor and the effect of nitric oxide synthase inhibition during hypoxia in the cerebral cortex of newborn piglets. Zubrow, A.B., Numagami, Y., Fritz, K.I., Mishra, O.P., Delivoria-Papadopoulos, M. Brain Res. (2000) [Pubmed]
  11. Effect of N-methyl-D-aspartate receptor blockade on the control of cerebral O2 supply/consumption balance during hypoxia in newborn pigs. Williams, J.A., Colon, R.J., Weiss, H.R. Neurochem. Res. (1998) [Pubmed]
  12. Long-lasting potentiation of synaptic transmission in the Schaffer collateral-commissural pathway of the guinea pig hippocampus by activation of postsynaptic N-methyl-D-aspartate receptor. Kamiya, H., Sawada, S., Yamamoto, C. Synapse (1993) [Pubmed]
  13. Expression of phosphorylation of N-methyl-D-aspartate receptor subunits during graded hypoxia in the cerebral cortex of newborn piglets. Fritz, K.I., Ashraf, Q.M., Zubrow, A.B., Mishra, O.P., Delivoria-Papadopoulos, M. Biol. Neonate (2004) [Pubmed]
  14. Zinc deficiency decreases the concentration of N-methyl-D-aspartate receptors in guinea pig cortical synaptic membranes. Browning, J.D., O'Dell, B.L. J. Nutr. (1995) [Pubmed]
  15. N-methyl-D-aspartate receptor-mediated contractions of the guinea pig ileum longitudinal muscle/myenteric plexus preparation: modulation by phencyclidine and glycine receptors. Campbell, B.G., Couceyro, P., Keana, J.F., Weber, E. J. Pharmacol. Exp. Ther. (1991) [Pubmed]
  16. The role of N-methyl-D-aspartate receptor in the guinea pig inner ear after unilateral labyrinthectomy. Shimogori, H., Yamashita, H., Takahashi, M. Neurosci. Lett. (1998) [Pubmed]
  17. Specific glutathione binding sites in pig cerebral cortical synaptic membranes. Janáky, R., Shaw, C.A., Varga, V., Hermann, A., Dohovics, R., Saransaari, P., Oja, S.S. Neuroscience (2000) [Pubmed]
  18. The in vivo effect of bilirubin on the N-methyl-D-aspartate receptor/ion channel complex in the brains of newborn piglets. Hoffman, D.J., Zanelli, S.A., Kubin, J., Mishra, O.P., Delivoria-Papadopoulos, M. Pediatr. Res. (1996) [Pubmed]
  19. Cochlear protection from carbon monoxide exposure by free radical blockers in the guinea pig. Fechter, L.D., Liu, Y., Pearce, T.A. Toxicol. Appl. Pharmacol. (1997) [Pubmed]
  20. Peroxynitrite-induced modification of the N-methyl-D-aspartate receptor in the cerebral cortex of the guinea pig fetus at term. Zanelli, S.A., Ashraf, Q.M., Delivoria-Papadopoulos, M., Mishra, O.P. Neurosci. Lett. (2000) [Pubmed]
  21. Kappa opioid receptor tolerance in the guinea pig hippocampus. Jin, W., Terman, G.W., Chavkin, C. J. Pharmacol. Exp. Ther. (1997) [Pubmed]
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