Chemical Compound Review:
Quisqualate (2S)-2-amino-3-(3,5-dioxo- 1,2,4...
Synonyms:
Tocris-0188, CHEMBL279956, SureCN136819, Q2128_SIGMA, CCG-205116, ...
- Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Turski, L., Bressler, K., Rettig, K.J., Löschmann, P.A., Wachtel, H. Nature (1991)
- Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake. Murphy, T.H., Schnaar, R.L., Coyle, J.T. FASEB J. (1990)
- Muscarinic and quisqualate receptor-induced phosphoinositide hydrolysis in primary cultures of striatal and hippocampal neurons. Evidence for differential mechanisms of activation. Ambrosini, A., Meldolesi, J. J. Neurochem. (1989)
- Glutamate receptors of ganglion cells in the rabbit retina: evidence for glutamate as a bipolar cell transmitter. Massey, S.C., Miller, R.F. J. Physiol. (Lond.) (1988)
- Phosphoinositide breakdown in rat hippocampal slices: sensitivity to glutamate induced by in vitro anoxia. Ninomiya, H., Taniguchi, T., Fujiwara, M. J. Neurochem. (1990)
- Selective reduction of quisqualate (AMPA) receptors in Alzheimer cerebellum. Dewar, D., Chalmers, D.T., Shand, A., Graham, D.I., McCulloch, J. Ann. Neurol. (1990)
- Preventive action of quisqualic acid against grayanotoxin-induced suppression of locomotor activity in mice. Ohgaki, T., Uchida, S., Meguri, H., Ogita, K., Yoneda, Y. Neuropharmacology (1988)
- Anticonvulsant profile of MDL 27,266: an orally active, broad-spectrum anticonvulsant agent. White, H.S., Patel, S., Meldrum, B.S. Epilepsy Res. (1992)
- Simple and configural association learning in rats with bilateral quisqualic acid lesions of the nucleus basalis magnocellularis. Butt, A.E., Hodge, G.K. Behav. Brain Res. (1997)
- Globus pallidus and motor initiation: the bilateral effects of unilateral quisqualic acid-induced lesion on reaction times in monkeys. Alamy, M., Trouche, E., Nieoullon, A., Legallet, E. Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. (1994)
- Arachidonic acid released from striatal neurons by joint stimulation of ionotropic and metabotropic quisqualate receptors. Dumuis, A., Pin, J.P., Oomagari, K., Sebben, M., Bockaert, J. Nature (1990)
- Temporally distinct pre- and post-synaptic mechanisms maintain long-term potentiation. Davies, S.N., Lester, R.A., Reymann, K.G., Collingridge, G.L. Nature (1989)
- Neurobiology. Quisqualate receptor antagonists. Foster, A.C. Nature (1988)
- A new type of glutamate receptor linked to inositol phospholipid metabolism. Sugiyama, H., Ito, I., Hirono, C. Nature (1987)
- Perinatal hypoxic-ischemic brain injury enhances quisqualic acid-stimulated phosphoinositide turnover. Chen, C.K., Silverstein, F.S., Fisher, S.K., Statman, D., Johnston, M.V. J. Neurochem. (1988)
- Different types of glutamate receptors in isolated and identified neurones of the mollusc Planorbarius corneus. Bolshakov VYu, n.u.l.l., Gapon, S.A., Magazanik, L.G. J. Physiol. (Lond.) (1991)
- HU-211, a non-psychotropic cannabinoid, rescues cortical neurones from excitatory amino acid toxicity in culture. Eshhar, N., Striem, S., Biegon, A. Neuroreport (1993)
- HA-966 (1-hydroxy-3-aminopyrrolidone-2) selectively reduces N-methyl-D-aspartate (NMDA)-mediated brain damage. McDonald, J.W., Uckele, J., Silverstein, F.S., Johnston, M.V. Neurosci. Lett. (1989)
- Alterations in L-glutamate binding in Alzheimer's and Huntington's diseases. Greenamyre, J.T., Penney, J.B., Young, A.B., D'Amato, C.J., Hicks, S.P., Shoulson, I. Science (1985)
- Modulation of the N-methyl-D-aspartate channel by extracellular H+. Tang, C.M., Dichter, M., Morad, M. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Modulation of DL-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/quisqualate receptors by phospholipase A2: a necessary step in long-term potentiation? Massicotte, G., Vanderklish, P., Lynch, G., Baudry, M. Proc. Natl. Acad. Sci. U.S.A. (1991)
- Coexpression of N-methyl-D-aspartate and phencyclidine receptors in Xenopus oocytes injected with rat brain mRNA. Kushner, L., Lerma, J., Zukin, R.S., Bennett, M.V. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase. Carter, R.E., Feldman, A.R., Coyle, J.T. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Hyperpolarization of fish retinal horizontal cells by kainate and quisqualate. Hankins, M.W., Ruddock, K.H. Nature (1984)
- NMDA receptors activate the arachidonic acid cascade system in striatal neurons. Dumuis, A., Sebben, M., Haynes, L., Pin, J.P., Bockaert, J. Nature (1988)
- Intradendritic release of calcium induced by glutamate in cerebellar Purkinje cells. Llano, I., Dreessen, J., Kano, M., Konnerth, A. Neuron (1991)
- Postsynaptic Hebbian and non-Hebbian long-term potentiation of synaptic efficacy in the entorhinal cortex in slices and in the isolated adult guinea pig brain. Alonso, A., de Curtis, M., Llinás, R. Proc. Natl. Acad. Sci. U.S.A. (1990)
- Activation of protein kinase C differentially modulates neuronal Na+, Ca2+, and gamma-aminobutyrate type A channels. Sigel, E., Baur, R. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Murphy, T.H., Miyamoto, M., Sastre, A., Schnaar, R.L., Coyle, J.T. Neuron (1989)
- Quisqualate and L-glutamate inhibit retinal horizontal-cell responses to kainate. Ishida, A.T., Neyton, J. Proc. Natl. Acad. Sci. U.S.A. (1985)
- Selective association of N-methyl aspartate and quisqualate types of L-glutamate receptor with brain postsynaptic densities. Fagg, G.E., Matus, A. Proc. Natl. Acad. Sci. U.S.A. (1984)
- L-glutamate-induced depolarization in solitary photoreceptors: a process that may contribute to the interaction between photoreceptors in situ. Tachibana, M., Kaneko, A. Proc. Natl. Acad. Sci. U.S.A. (1988)
- Aniracetam reduces glutamate receptor desensitization and slows the decay of fast excitatory synaptic currents in the hippocampus. Isaacson, J.S., Nicoll, R.A. Proc. Natl. Acad. Sci. U.S.A. (1991)
- The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells. Chavis, P., Shinozaki, H., Bockaert, J., Fagni, L. J. Neurosci. (1994)
- Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues. Hermit, M.B., Greenwood, J.R., Bräuner-Osborne, H. J. Biol. Chem. (2004)
- Expression of functional mGlu5 metabotropic glutamate receptors in human melanocytes. Frati, C., Marchese, C., Fisichella, G., Copani, A., Nasca, M.R., Storto, M., Nicoletti, F. J. Cell. Physiol. (2000)
- Metabotropic glutamate receptor agonists alter neuronal excitability and Ca2+ levels via the phospholipase C transduction pathway in cultured Purkinje neurons. Netzeband, J.G., Parsons, K.L., Sweeney, D.D., Gruol, D.L. J. Neurophysiol. (1997)
- LY341495 is a nanomolar potent and selective antagonist of group II metabotropic glutamate receptors. Kingston, A.E., Ornstein, P.L., Wright, R.A., Johnson, B.G., Mayne, N.G., Burnett, J.P., Belagaje, R., Wu, S., Schoepp, D.D. Neuropharmacology (1998)
- Visual responses in adult cat visual cortex depend on N-methyl-D-aspartate receptors. Miller, K.D., Chapman, B., Stryker, M.P. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Non-NMDA receptor-mediated neurotoxicity in cortical culture. Koh, J.Y., Goldberg, M.P., Hartley, D.M., Choi, D.W. J. Neurosci. (1990)
- Selectivity of amino acid transmitters acting at N-methyl-D-aspartate and amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptors. Curras, M.C., Dingledine, R. Mol. Pharmacol. (1992)
- Spinal and supraspinal changes in opioid mRNA expression are related to the onset of pain behaviors following excitotoxic spinal cord injury. Abraham, K.E., McGinty, J.F., Brewer, K.L. Pain (2001)
- Changes in excitatory amino acid receptor binding in the intact and decorticated rat neostriatum following insulin-induced hypoglycemia. Westerberg, E., Wieloch, T.W. J. Neurochem. (1989)