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Gene Review

CRCT1  -  cysteine-rich C-terminal 1

Homo sapiens

Synonyms: C1orf42, Cysteine-rich C-terminal protein 1, NICE-1, NICE1, Protein NICE-1
 
 
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Disease relevance of CRCT1

  • Last year alone saw an international workshop on Cardiac MEF & Arrhythmias at Oxford, as well as dedicated sessions at NASPE's 23rd annual meeting in San Diego, CardioStim 2002 in Nice, and the UK Physiological Society meeting in Leeds [1].
  • Results of proton therapy of uveal melanomas treated in Nice [2].
  • METHODS AND MATERIALS: Between 1975 and 1996 at Marseille and Nice Cancer Institutes, 4026 patients received lumpectomy and radiotherapy (RT) (50-80 Gy) for a localized breast cancer of which 473 presented a LR [3].
  • DESIGN AND PATIENTS: A group of 41 men with normal classical semen parameters, included in the IVF program of University of Nice for feminine tubal obstruction (n = 37) or unexplained infertility (n = 4), were evaluated in a prospective study and compared with a control group of 10 fertile donors [4].
  • The aim of this study was to investigate TEM-24-producing isolates of Klebsiella pneumoniae, and their clonal dissemination in Nice University Hospital. During the 1994-2000 period, a total of 263 non-repetitive isolates of ESBL-producing K. pneumoniae were collected [5].
 

Psychiatry related information on CRCT1

  • ECNP consensus meeting. Negative, depressive and cognitive symptoms of schizophrenia. Nice, March 2004 [6].
  • ECNP Consensus Meeting March 2000 Nice: guidelines for investigating efficacy in bipolar disorder. European College of Neuropsychopharmacology [7].
  • ECNP consensus meeting, March 5-6, 1999, Nice. Post traumatic stress disorder: guidelines for investigating efficacy of pharmacological intervention. ECNP and ECST [8].
  • Rett syndrome: genetic horizons. Report on a satellite symposium at the 3rd Congress of the European Paediatric Neurology Society Nice, November, 1999 [9].
  • In order to bring more coherence to approaches the management of these universally troubling complications, a group of international clinical experts in dementia, convened this year in Nice and then in Paris in an attempt to find a general consensus of recommended behavioral and psychiatric interventions in dementia [10].
 

High impact information on CRCT1

  • The determination of the location of the mutation in spectrin Nice points to specific regions of the beta-spectrin chain where phosphorylation may occur [11].
  • Expression of NICE-1 was up-regulated in differentiated keratinocytes, pointing to its relevance for the terminal differentiation of the epidermis [12].
  • Factors X Nice I and II: two novel missense mutations (Met-40Val and Pro304Ser) in patient with coagulation factor X deficiency [13].
  • METHODS: Records concerning 480 outpatients attending the Rheumatology Department of the University Hospital of Nice (France) for RA or SA were retrospectively reviewed for the duration of disease, treatment, serological status and biological data [14].
  • A Nice development: The first joint meeting of the British and French Societies for Developmental Biology, 13-16th September, 2003, Nice, France [15].
 

Biological context of CRCT1

  • The new additions include: concept of virtual databases, integration of XML databases like the Integrated Resource of Protein Domains and Functional Sites (InterPro), Gene Ontology (GO), MEDLINE, Metabolic pathways, etc., user friendly data representation in 'Nice views', SRSQuickSearch bookmarklets [16].
  • SETTING: Dermatology department at a university hospital in Nice, France. PATIENTS: Ten patients with histologically proved EOLP that was refractory to treatment [17].
  • Report of the Sixth International Workshop on Human Chromosome 11 Mapping 1998. Nice, France, May 2-5, 1998 [18].
  • Congress of the European Academy of Dermatology and Venereology, 7-11 October 1998, Nice, France [19].
  • The incineration plant of the Nice district is identified as a possible major source of airborne anthropogenic P [20].
 

Anatomical context of CRCT1

  • METHODS: Reconstituted human oral epithelium (Skinethic Laboratory, Nice, France) was inoculated with C. albicans SC5314 and incubated up to 48 h [21].
  • Necropsy findings in 395 adult patients with the acquired immunodeficiency syndrome (AIDS) who died in Nice, France, between March 1983 and May 1996 were compared retrospectively with antemortem diagnoses, risk factors and number of positive T CD4 lymphocytes at the time of death [22].
  • AIM: The aim of this study was to determine the periapical status and the quality of root-canal treatment amongst an adult population attending the dental school in Nice, France during 1998 [23].
 

Associations of CRCT1 with chemical compounds

  • Patients enrolled in the National Investigators Collaborating on Enoxaparin 1 (NICE-1) trial received enoxaparin as a 1.0-mg/kg intravenous bolus [24].
  • HPV infections and cervical cancer prevention. Priorities and new directions. Highlights of EUROGIN 2004 International Expert Meeting, Nice, France, October 21-23, 2004 [25].
  • Proteins recovered from gels by electrophoretic elution required further purification by inverse-gradient RP-HPLC [R. J. Simpson, R. L. Moritz, E. C. Nice and B. Grego, Eur. J. Biochem., 165 (1987) 21] to remove sodium dodecylsulphate and acrylamide-related contaminants for sequence analysis [26].
  • During the Nice Triathlon (June 26, 1994), the serum levels of type I myosin heavy chain (MHC) fragments and creatine kinase (CK and CK-MB) activities were assessed in 12 athletes in order to evaluate the exercise-induced muscle damage [27].
  • Thermoluminescent dosimeter TLD-600 and TLD-700 were used to determine the thermal neutron flux within a Plexiglas phantom irradiated under the Nice Biomedical Cyclotron p(60)+Be(32) fast neutron beam [28].
 

Other interactions of CRCT1

  • Patients in NICE 1 were administered enoxaparin 1.0 mg/kg intravenously (without abciximab) and those enrolled in NICE 4 were administered a reduced dose (0.75 mg/kg) of enoxaparin in combination with standard-dose abciximab intravenously during PCI [29].
 

Analytical, diagnostic and therapeutic context of CRCT1

  • Since algorithms for integrating these pharmacotherapies have not been determined, patients undergoing elective PCI were enrolled into 2 distinct and separate studies conducted by the National Investigators Collaborating on Enoxaparin (NICE) study groups (NICE 1 and NICE 4 studies) [29].
  • Among these patients, 69 (14.6%) received a second lumpectomy followed by IB, which delivered 30 Gy (Nice, n = 24) or 45-50 Gy (Marseille, n = 45) with 3 to 8 (192)Ir wires in 1 or 2 planes on the 85% isodose [3].
  • For two years now, a study on intensity modulated radiotherapy (IMRT) has been in progress at the Antoine Lacassagne Hospital Center for Cancer Therapy (in Nice) in collaboration with the University of Nice-Sophia Antipolis [30].
  • Relevance and complications of intravenous infusion at the emergency unit at Nice university hospital [31].
  • METHODS: In this retrospective study, 224 consecutive incident cases were treated at the Biomedical Cyclotron Centre (Nice, France) from June 1991 to December 1997 [32].

References

  1. Cardiac mechano-electric feedback: past, present, and prospect. Kohl, P., Ravens, U. Prog. Biophys. Mol. Biol. (2003) [Pubmed]
  2. Results of proton therapy of uveal melanomas treated in Nice. Courdi, A., Caujolle, J.P., Grange, J.D., Diallo-Rosier, L., Sahel, J., Bacin, F., Zur, C., Gastaud, P., Iborra-Brassart, N., Hérault, J., Chauvel, P. Int. J. Radiat. Oncol. Biol. Phys. (1999) [Pubmed]
  3. Partial breast irradiation as second conservative treatment for local breast cancer recurrence. Hannoun-Levi, J.M., Houvenaeghel, G., Ellis, S., Teissier, E., Alzieu, C., Lallement, M., Cowen, D. Int. J. Radiat. Oncol. Biol. Phys. (2004) [Pubmed]
  4. Dynamics of human sperm acrosome reaction: relation with in vitro fertilization. Fénichel, P., Donzeau, M., Farahifar, D., Basteris, B., Ayraud, N., Hsi, B.L. Fertil. Steril. (1991) [Pubmed]
  5. A seven-year survey of Klebsiella pneumoniae producing TEM-24 extended-spectrum beta-lactamase in Nice University Hospital (1994-2000). Giraud-Morin, C., Fosse, T. J. Hosp. Infect. (2003) [Pubmed]
  6. ECNP consensus meeting. Negative, depressive and cognitive symptoms of schizophrenia. Nice, March 2004. Montgomery, S.A., van Zwieten-Boot, B. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology (2007) [Pubmed]
  7. ECNP Consensus Meeting March 2000 Nice: guidelines for investigating efficacy in bipolar disorder. European College of Neuropsychopharmacology. Montgomery, D.B. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2001) [Pubmed]
  8. ECNP consensus meeting, March 5-6, 1999, Nice. Post traumatic stress disorder: guidelines for investigating efficacy of pharmacological intervention. ECNP and ECST. Montgomery, S., Bech, P. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. (2000) [Pubmed]
  9. Rett syndrome: genetic horizons. Report on a satellite symposium at the 3rd Congress of the European Paediatric Neurology Society Nice, November, 1999. Percy, A. Eur. J. Paediatr. Neurol. (2000) [Pubmed]
  10. Editorial: management of behavioral and psychiatric symptoms in dementia. Fitten, L.J. The journal of nutrition, health & aging. (2006) [Pubmed]
  11. An insertional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin nice (beta 220/216). Tse, W.T., Gallagher, P.G., Pothier, B., Costa, F.F., Scarpa, A., Delaunay, J., Forget, B.G. Blood (1991) [Pubmed]
  12. Identification of human epidermal differentiation complex (EDC)-encoded genes by subtractive hybridization of entire YACs to a gridded keratinocyte cDNA library. Marenholz, I., Zirra, M., Fischer, D.F., Backendorf, C., Ziegler, A., Mischke, D. Genome Res. (2001) [Pubmed]
  13. Factors X Nice I and II: two novel missense mutations (Met-40Val and Pro304Ser) in patient with coagulation factor X deficiency. Miyata, T., Fischer, F., Umeyama, H., Appert, A., Jambou, D., Kato, H. Thromb. Haemost. (1998) [Pubmed]
  14. Safety of anti-TNF-{alpha} therapy in rheumatoid arthritis and spondylarthropathies with concurrent B or C chronic hepatitis. Roux, C.H., Brocq, O., Breuil, V., Albert, C., Euller-Ziegler, L. Rheumatology (Oxford, England) (2006) [Pubmed]
  15. A Nice development: The first joint meeting of the British and French Societies for Developmental Biology, 13-16th September, 2003, Nice, France. Brown, J., Chazaud, C., Irving, C. Dev. Dyn. (2004) [Pubmed]
  16. The EBI SRS server-new features. Zdobnov, E.M., Lopez, R., Apweiler, R., Etzold, T. Bioinformatics (2002) [Pubmed]
  17. Treatment of chronic erosive oral lichen planus with low concentrations of topical tacrolimus: an open prospective study. Olivier, V., Lacour, J.P., Mousnier, A., Garraffo, R., Monteil, R.A., Ortonne, J.P. Archives of dermatology. (2002) [Pubmed]
  18. Report of the Sixth International Workshop on Human Chromosome 11 Mapping 1998. Nice, France, May 2-5, 1998. Gaudray, P., Carle, G.F., Gerhard, D.S., Gessler, M., Mannens, M.M., Athanasiou, M., Bliek, J., Calender, A., Debelenko, L.V., Devignes, M., Evans, G.A., Favier, R., Forbes, S., Gaudray, G., Gawin, B., Gordon, M., Grimmond, S., Grossfeld, P., Harris, J., Hattori, M., Hosoda, F., Hummerich, H., James, M., Kalla, J., Katsanis, N. Cytogenet. Cell Genet. (1999) [Pubmed]
  19. Congress of the European Academy of Dermatology and Venereology, 7-11 October 1998, Nice, France. Bewley, A.P. Clin. Exp. Dermatol. (1999) [Pubmed]
  20. Atmospheric input of anthropogenic phosphorus to the northwest Mediterranean under oligotrophic conditions. Migon, C., Sandroni, V., Béthoux, J.P. Mar. Environ. Res. (2001) [Pubmed]
  21. An ultrastructural and a cytochemical study of candidal invasion of reconstituted human oral epithelium. Jayatilake, J.A., Samaranayake, Y.H., Samaranayake, L.P. J. Oral Pathol. Med. (2005) [Pubmed]
  22. Autopsy findings in the acquired immunodeficiency syndrome (AIDS). A report of 395 cases from the south of France. Hofman, P., Saint-Paul, M.C., Battaglione, V., Michiels, J.F., Loubière, R. Pathol. Res. Pract. (1999) [Pubmed]
  23. Periapical status, prevalence and quality of endodontic treatment in an adult French population. Lupi-Pegurier, L., Bertrand, M.F., Muller-Bolla, M., Rocca, J.P., Bolla, M. International endodontic journal. (2002) [Pubmed]
  24. Pharmacokinetics of enoxaparin in patients undergoing percutaneous coronary intervention with and without glycoprotein IIb/IIIa therapy. Argenti, D., Hoppensteadt, D., Heald, D., Jensen, B., Fareed, J. American journal of therapeutics. (2003) [Pubmed]
  25. HPV infections and cervical cancer prevention. Priorities and new directions. Highlights of EUROGIN 2004 International Expert Meeting, Nice, France, October 21-23, 2004. Monsonego, J. Gynecol. Oncol. (2005) [Pubmed]
  26. Strategies for internal amino acid sequence analysis of proteins separated by polyacrylamide gel electrophoresis. Ward, L.D., Reid, G.E., Moritz, R.L., Simpson, R.J. J. Chromatogr. (1990) [Pubmed]
  27. Effects of strenuous exercise on serum myosin heavy chain fragments in male triathletes. Prou, E., Margaritis, I., Tessier, F., Marini, J.F. International journal of sports medicine. (1996) [Pubmed]
  28. Boron neutron capture enhancement (BNCE) of fast neutron irradiation for glioblastoma: increase of thermal neutron flux with heavy material collimation, a theoretical evaluation. Paquis, P., Pignol, J.P., Lonjon, M., Brassart, N., Courdi, A., Chauvel, P., Grellier, P., Chatel, M. J. Neurooncol. (1999) [Pubmed]
  29. Enoxaparin and abciximab adjunctive pharmacotherapy during percutaneous coronary intervention. Kereiakes, D.J., Grines, C., Fry, E., Esente, P., Hoppensteadt, D., Midei, M., Barr, L., Matthai, W., Todd, M., Broderick, T., Rubinstein, R., Fareed, J., Santoian, E., Neiderman, A., Brodie, B., Zidar, J., Ferguson, J.J., Cohen, M. The Journal of invasive cardiology. (2001) [Pubmed]
  30. Validation of intensity modulation on a commercial treatment planning system. Martin, E., Hachem, A., Marcié, S., Hérault, J., Costa, A., Bensadoun, R.J., Lagrange, J.L. Medical physics. (2003) [Pubmed]
  31. Relevance and complications of intravenous infusion at the emergency unit at Nice university hospital. Vandenbos, F., Basar, A., Tempesta, S., Fournier, J.P., Bertrand, F., Vanesland, L., Oualid, H., Dunais, B., Dellamonica, P., Roger, P.M. J. Infect. (2003) [Pubmed]
  32. Survival after proton-beam irradiation of uveal melanomas. Kodjikian, L., Roy, P., Rouberol, F., Garweg, J.G., Chauvel, P., Manon, L., Jean-Louis, B., Little, R.E., Sasco, A.J., Grange, J.D. Am. J. Ophthalmol. (2004) [Pubmed]
 
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