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ZNF331  -  zinc finger protein 331

Homo sapiens

Synonyms: C2H2-like zinc finger protein rearranged in thyroid adenomas, RITA, ZNF361, ZNF463, Zinc finger protein 331, ...
 
 
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Disease relevance of ZNF331

  • A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas [1].
  • Interventional versus conservative treatment for patients with unstable angina or non-ST-elevation myocardial infarction: the British Heart Foundation RITA 3 randomised trial. Randomized Intervention Trial of unstable Angina [2].
  • AIMS: The RITA 3 trial randomized patients with non-ST-elevation myocardial infarction or unstable angina to strategies of early intervention (angiography followed by revascularization) or conservative care (ischaemia or symptom driven angiography) [3].
  • METHODS: Twenty patients with lung metastases from CRC were treated with a RITA Starburst XL electrode and RITA 1500 generator using temperature control and impedance monitoring [4].
  • Provision of health care to patients during and after events like those which occurred in association with hurricanes Katrina and Rita poses particular difficulties for rare disease patients, including those with genetic/metabolic diseases [5].
 

Psychiatry related information on ZNF331

 

High impact information on ZNF331

  • RITA induced expression of p53 target genes and massive apoptosis in various tumor cells lines expressing wild-type p53 [8].
  • RITA suppressed the growth of human fibroblasts and lymphoblasts only upon oncogene expression and showed substantial p53-dependent antitumor effect in vivo [8].
  • Rita Levi-Montalcini: the discovery of nerve growth factor and modern neurobiology [9].
  • Several randomized clinical trials (CABRI, RITA, GABI, EAST, BARI) currently in progress are comparing PTCA and CABG in the management of patients with multivessel coronary artery disease [10].
  • From the close vicinity to the breakpoint region, the expression patterns of the gene, and its type, we consider RITA a strong candidate target gene of the specific 19q aberrations in benign thyroid tumors [11].
 

Chemical compound and disease context of ZNF331

 

Biological context of ZNF331

  • The gene that we tentatively refer to as RITA (rearranged in thyroid adenomas) belongs to the KRAB zinc finger protein coding genes [11].
  • As from Northern blot analysis ZNF463 is only expressed in testis, RT-PCR indicates that ZNF463 is expressed more highly in normal fertile adults than in fetus and azoospermic patients suggesting that it may play a role in human spermatogenesis [13].
  • Stamp vignette on medical science. Rita Levi-Montalcini--Nobel Prize for work in neurology [14].
  • The different cell types in the opercular epidermis of Rita rita when exposed to a synthetic detergent, dodecylbenzene sodium sulfonate in the concentration of 6.9 mg liter-1 (96-hr LC50 of the detergent), had a gradual decrease in the activity of various enzymes responsible for different metabolic processes occurring inside the cell [15].
  • Lessons from Hurricane Rita: organizing to provide medical care during a natural disaster [16].
 

Anatomical context of ZNF331

 

Associations of ZNF331 with chemical compounds

  • Six genes were selected for confirmation by real-time PCR, and of these, CXCL16, ZNF331, JUN, and PF4 were the most significantly affected by benzene exposure, a finding that was confirmed in a larger data set from 28 subjects [21].
  • Fish, Rita rita, were exposed to an anionic detergent, dodecylbenzene sodium sulfonate, 6.9 mg per litre of tap water (96-hr LC50 of the detergent) [17].
  • In this first article for the feature Humanism and Medicine, Rita Charon introduces an excerpt from Richard Selzer's introduction to his latest book, The Doctor Stories [22].
  • RITA 3 has been assigned the International Standard Randomised Control Trial Number ISRCTN07752711 [23].
  • Carbon monoxide poisoning following a natural disaster: a report on hurricane rita [24].
 

Analytical, diagnostic and therapeutic context of ZNF331

  • A novel human KRAB (Krüppel associated box) type zinc finger protein encoding gene, ZNF463, was obtained by mRNA differential display and RACE [13].
  • RITA nine-array 5 cm thermal ablation catheter and the model 1500 generator were used [25].
  • Assessing fatigue and self-care strategies in patients receiving radiotherapy for non-small-cell lung cancer, by Diana Borthwick, Gillian Knowles Shanne McNamara, Rita O'Dea, Paul Stroner [European Journal of Oncology Nursing 7(4), 231-241] [26].
  • Assessing fatigue and self-care strategies in patients receiving radiotherapy for non-small-cell lung cancer, by Diana Borthwick, Gillian Knowles Shanne McNamara, Rita O'Dea, Paul Stroner [European Journal of Oncology Nursing 7(4), 231-241] [27].
  • Blood flow in the distal RITA was assessed by parasternal transthoracic Doppler ultrasonography [28].

References

  1. A 3.4-kbp transcript of ZNF331 is solely expressed in follicular thyroid adenomas. Meiboom, M., Murua Escobar, H., Pentimalli, F., Fusco, A., Belge, G., Bullerdiek, J. Cytogenet. Genome Res. (2003) [Pubmed]
  2. Interventional versus conservative treatment for patients with unstable angina or non-ST-elevation myocardial infarction: the British Heart Foundation RITA 3 randomised trial. Randomized Intervention Trial of unstable Angina. Fox, K.A., Poole-Wilson, P.A., Henderson, R.A., Clayton, T.C., Chamberlain, D.A., Shaw, T.R., Wheatley, D.J., Pocock, S.J. Lancet (2002) [Pubmed]
  3. Do men benefit more than women from an interventional strategy in patients with unstable angina or non-ST-elevation myocardial infarction? The impact of gender in the RITA 3 trial. Clayton, T.C., Pocock, S.J., Henderson, R.A., Poole-Wilson, P.A., Shaw, T.R., Knight, R., Fox, K.A. Eur. Heart J. (2004) [Pubmed]
  4. Percutaneous radiofrequency ablation of pulmonary metastases in patients with colorectal cancer. King, J., Glenn, D., Clark, W., Zhao, J., Steinke, K., Clingan, P., Morris, D.L. The British journal of surgery. (2004) [Pubmed]
  5. Genetic/metabolic health care delivery during and after hurricanes Katrina and Rita. Andersson, H.C., Narumanchi, T.C., Cunningham, A., Bowdish, B., Thoene, J. Mol. Genet. Metab. (2006) [Pubmed]
  6. Rita Kennedy: case analysis for decision-making. Wood, V., Rubin, S. Nurse education today. (1992) [Pubmed]
  7. Mental health and recovery in the Gulf Coast after Hurricanes Katrina and Rita. Weisler, R.H., Barbee, J.G., Townsend, M.H. JAMA (2006) [Pubmed]
  8. Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Issaeva, N., Bozko, P., Enge, M., Protopopova, M., Verhoef, L.G., Masucci, M., Pramanik, A., Selivanova, G. Nat. Med. (2004) [Pubmed]
  9. Rita Levi-Montalcini: the discovery of nerve growth factor and modern neurobiology. Aloe, L. Trends Cell Biol. (2004) [Pubmed]
  10. Coronary artery bypass surgery vs coronary angioplasty: from antithesis to synthesis. Dimas, A.P., Healy, B. Eur. Heart J. (1989) [Pubmed]
  11. A KRAB zinc finger protein gene is the potential target of 19q13 translocation in benign thyroid tumors. Rippe, V., Belge, G., Meiboom, M., Kazmierczak, B., Fusco, A., Bullerdiek, J. Genes Chromosomes Cancer (1999) [Pubmed]
  12. Toxicity of an anionic detergent, dodecylbenzene sodium sulfonate, to a freshwater fish, Rita rita: determination of LC50 values by different methods. Roy, D. Ecotoxicol. Environ. Saf. (1988) [Pubmed]
  13. Isolation, characterization, and mapping of a novel human KRAB zinc finger protein encoding gene ZNF463. Wu, H., Zhang, S., Qiu, W., Zhang, G., Xia, Q., Xiao, C., Huang, X., Huang, M., Agen, P., Fan, T., Yang, J., Milunsky, A. Biochim. Biophys. Acta (2001) [Pubmed]
  14. Stamp vignette on medical science. Rita Levi-Montalcini--Nobel Prize for work in neurology. Shampo, M.A., Kyle, R.A. Mayo Clin. Proc. (2003) [Pubmed]
  15. Detergent-induced changes in the mapping of certain enzymes in various cell types of Rita rita. I. Opercular epidermis. Roy, D. Ecotoxicol. Environ. Saf. (1989) [Pubmed]
  16. Lessons from Hurricane Rita: organizing to provide medical care during a natural disaster. Walsh, T.J., Orsega, S., Banks, D. Ann. Intern. Med. (2006) [Pubmed]
  17. Impact of detergents on the protein histochemistry of various cell types of the gill epithelium of Rita rita. Roy, D. Ecotoxicol. Environ. Saf. (1988) [Pubmed]
  18. Relationship between the preoptico hypophysial system and the vascular system in the teleost Rita rita (Ham.). Sathyanesan, A.G., Das, R.C. J. Neural Transm. (1975) [Pubmed]
  19. A note on the cavdal neurosecretory system and seasonal changes observed in the urophysis of Rita rita (Blecker). Sharma, S., Sharma, A. Can. J. Zool. (1975) [Pubmed]
  20. Repeat median sternotomy after prior ante-aortic crossover right internal thoracic artery grafting. Lev-Ran, O., Mohr, R., Aviram, G., Matsa, M., Nesher, N., Pevni, D., Uretzky, G. Journal of cardiac surgery. (2004) [Pubmed]
  21. Discovery of novel biomarkers by microarray analysis of peripheral blood mononuclear cell gene expression in benzene-exposed workers. Forrest, M.S., Lan, Q., Hubbard, A.E., Zhang, L., Vermeulen, R., Zhao, X., Li, G., Wu, Y.Y., Shen, M., Yin, S., Chanock, S.J., Rothman, N., Smith, M.T. Environ. Health Perspect. (2005) [Pubmed]
  22. Stories for a humanistic medicine. Selzer, R., Charon, R. Academic medicine : journal of the Association of American Medical Colleges. (1999) [Pubmed]
  23. 5-year outcome of an interventional strategy in non-ST-elevation acute coronary syndrome: the British Heart Foundation RITA 3 randomised trial. Fox, K.A., Poole-Wilson, P., Clayton, T.C., Henderson, R.A., Shaw, T.R., Wheatley, D.J., Knight, R., Pocock, S.J. Lancet (2005) [Pubmed]
  24. Carbon monoxide poisoning following a natural disaster: a report on hurricane rita. Audin, C. Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association. (2006) [Pubmed]
  25. Radiofrequency ablation for the management of liver tumors. Bachar, G.N., Greif, F., Mor, E., Tur-Kaspa, R., Belenky, A. Isr. Med. Assoc. J. (2003) [Pubmed]
  26. Assessing fatigue and self-care strategies in patients receiving radiotherapy for non-small-cell lung cancer, by Diana Borthwick, Gillian Knowles Shanne McNamara, Rita O'Dea, Paul Stroner [European Journal of Oncology Nursing 7(4), 231-241]. Faithfull, S. European journal of oncology nursing : the official journal of European Oncology Nursing Society. (2004) [Pubmed]
  27. Assessing fatigue and self-care strategies in patients receiving radiotherapy for non-small-cell lung cancer, by Diana Borthwick, Gillian Knowles Shanne McNamara, Rita O'Dea, Paul Stroner [European Journal of Oncology Nursing 7(4), 231-241]. Krishnasamy, M. European journal of oncology nursing : the official journal of European Oncology Nursing Society. (2004) [Pubmed]
  28. Benefit of partial right-bilateral internal thoracic artery harvesting in patients at risk of sternal wound complications. Zeitani, J., Penta de Peppo, A., De Paulis, R., Nardi, P., Scafuri, A., Nardella, S., Chiariello, L. Ann. Thorac. Surg. (2006) [Pubmed]
 
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