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MeSH Review

Early Intervention (Education)

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Disease relevance of Early Intervention (Education)


Psychiatry related information on Early Intervention (Education)


High impact information on Early Intervention (Education)

  • Early interventions in the offspring of 2 generations affected with moderately to severely impairing MDD seem warranted [9].
  • In a 3 x 2 design, subjects were randomized to 1 of 3 medication strategies using fluphenazine decanoate under double-blind conditions: continuous moderate dose (standard) (12.5-50 mg every 2 weeks); continuous low dose (2.5-10 mg every 2 weeks); or targeted, early intervention (fluphenazine only when symptomatic) [10].
  • The lack of reversal of cardiac abnormalities and persistence of the F/P mutation in some patients suggests that early intervention with higher doses of imatinib mesylate may be desirable in the treatment of patients with MHES [11].
  • The effects of sumatriptan (300 microg/kg i.v.) on central sensitization induced by topical application of inflammatory soup (IS) on the dura were determined when the drug was administered either 2 h after IS (late intervention) or at the same time as IS (early intervention) [12].
  • IFN therapy was initiated 8 weeks after the onset of acute hepatitis in the early-intervention group and after 1 year of observation in the late-intervention group [13].

Chemical compound and disease context of Early Intervention (Education)


Biological context of Early Intervention (Education)


Anatomical context of Early Intervention (Education)

  • The expression of FASE in early lesions such as SCC associated uninvolved bronchial epithelium and epithelial hyperplasia might also provide a potential means for intervention early in the neoplastic process in the lung or even preventing their malignant transformation to invasive carcinomas [24].
  • The data suggest that, in order to be of therapeutic value in the treatment of acute spinal cord trauma, early intervention with high-dose intravenous methylprednisolone (30 to 40 mg/kg) is necessary, followed by intravenous maintenance dosing of 15 to 20 mg/kg every 2 to 3 hours [25].
  • The ability to use whole blood culture to estimate chemokine expression in T cell subsets may ultimately provide a practical means to evaluate disease status and to monitor early intervention therapies which target chemokines [26].
  • OBJECTIVE: To evaluate relations among measures of iron and zinc status, C-reactive protein (CRP), and leukocytes in low-income children participating in the Head Start program [27].
  • Prevention of oestradiol-associated toxicosis in a dalmatian by early intervention with granulocyte colony-stimulating factor [28].

Associations of Early Intervention (Education) with chemical compounds


Gene context of Early Intervention (Education)

  • We conclude that treatments that specifically inhibit the TNFR signaling pathway may present an opportunity for early intervention in peripherally transmitted TSEs [33].
  • These findings support the development of clinical trials of early intervention with FGFR3 inhibitors in t(4;14) myeloma [34].
  • Three disease-modifying agents approved in the last 18 months for early intervention in RA are etanercept, leflunomide, and infliximab [35].
  • Early interventions with 1,25(OH)2D3 could delay the onset of vitamin D resistance by preventing both 1,25(OH)2D3 deficiency and its critical consequence, reduction in VDR content [36].
  • If confirmed such developmental pathways might lead to preventive and early intervention strategies aimed at reducing the risk for PSUD in ADHD subjects [37].

Analytical, diagnostic and therapeutic context of Early Intervention (Education)


  1. Surrogate markers of atherosclerosis: impact of statins. Kastelein, J.J., Wiegman, A., de Groot, E. Atherosclerosis. Supplements. (2003) [Pubmed]
  2. Protective effects of captopril against ischemia/reperfusion-induced ventricular arrhythmias in vitro and in vivo. deGraeff, P.A., deLangen, C.D., van Gilst, W.H., Bel, K., Scholtens, E., Kingma, J.H., Wesseling, H. Am. J. Med. (1988) [Pubmed]
  3. Spontaneous hepatic rupture in rheumatoid arthritis. Hocking, W.G., Lasser, K., Ungerer, R., Bersohn, M., Palos, M., Spiegel, T. Arch. Intern. Med. (1981) [Pubmed]
  4. Sensory function and albumin excretion according to diagnostic criteria for diabetes. Sosenko, J.M., Kato, M., Goldberg, R.B. Diabetes Care (2004) [Pubmed]
  5. Gender difference in airway hyperresponsiveness in smokers with mild COPD. The Lung Health Study. Kanner, R.E., Connett, J.E., Altose, M.D., Buist, A.S., Lee, W.W., Tashkin, D.P., Wise, R.A. Am. J. Respir. Crit. Care Med. (1994) [Pubmed]
  6. Treatment for the parents of feminine boys. Newman, L.E. The American journal of psychiatry. (1976) [Pubmed]
  7. First-episode psychosis, early intervention, and outcome: what have we learned? Malla, A.K., Norman, R.M., Joober, R. Canadian journal of psychiatry. Revue canadienne de psychiatrie. (2005) [Pubmed]
  8. Does early intervention increase latency to relapse in major depressive disorder? Re-evaluation with cognitive behavior therapy. Quiring, J.M., Monroe, S.M., Simons, A.D., Thase, M.E. Journal of affective disorders. (2002) [Pubmed]
  9. Families at high and low risk for depression: a 3-generation study. Weissman, M.M., Wickramaratne, P., Nomura, Y., Warner, V., Verdeli, H., Pilowsky, D.J., Grillon, C., Bruder, G. Arch. Gen. Psychiatry (2005) [Pubmed]
  10. Relapse and rehospitalization during maintenance treatment of schizophrenia. The effects of dose reduction and family treatment. Schooler, N.R., Keith, S.J., Severe, J.B., Matthews, S.M., Bellack, A.S., Glick, I.D., Hargreaves, W.A., Kane, J.M., Ninan, P.T., Frances, A., Jacobs, M., Lieberman, J.A., Mance, R., Simpson, G.M., Woerner, M.G. Arch. Gen. Psychiatry (1997) [Pubmed]
  11. Molecular remission and reversal of myelofibrosis in response to imatinib mesylate treatment in patients with the myeloproliferative variant of hypereosinophilic syndrome. Klion, A.D., Robyn, J., Akin, C., Noel, P., Brown, M., Law, M., Metcalfe, D.D., Dunbar, C., Nutman, T.B. Blood (2004) [Pubmed]
  12. Analgesic triptan action in an animal model of intracranial pain: a race against the development of central sensitization. Burstein, R., Jakubowski, M. Ann. Neurol. (2004) [Pubmed]
  13. Short-term interferon-alfa therapy for acute hepatitis C: a randomized controlled trial. Nomura, H., Sou, S., Tanimoto, H., Nagahama, T., Kimura, Y., Hayashi, J., Ishibashi, H., Kashiwagi, S. Hepatology (2004) [Pubmed]
  14. Very early intervention with metoprolol in suspected acute myocardial infarction. Salathia, K.S., Barber, J.M., McIlmoyle, E.L., Nicholas, J., Evans, A.E., Elwood, J.H., Cran, G., Shanks, R.G., Boyle, D.M. Eur. Heart J. (1985) [Pubmed]
  15. Early versus delayed treatment of HIV infection. Zidovudine should be given before symptoms develop. Richman, D.D., Havlir, D. Drugs (1995) [Pubmed]
  16. Early intervention with high-dose acyclovir treatment during primary herpes simplex virus infection reduces latency and subsequent reactivation in the nervous system in vivo. Sawtell, N.M., Thompson, R.L., Stanberry, L.R., Bernstein, D.I. J. Infect. Dis. (2001) [Pubmed]
  17. Early treatment of a migraine attack while pain is still mild increases the efficacy of sumatriptan. Scholpp, J., Schellenberg, R., Moeckesch, B., Banik, N. Cephalalgia : an international journal of headache. (2004) [Pubmed]
  18. Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats. Brand, C.L., Sturis, J., Gotfredsen, C.F., Fleckner, J., Fledelius, C., Hansen, B.F., Andersen, B., Ye, J.M., Sauerberg, P., Wassermann, K. Am. J. Physiol. Endocrinol. Metab. (2003) [Pubmed]
  19. Beta-adrenergic blockade in acute myocardial infarction: a haemodynamic and radionuclide study. Murray, D.P., Murray, R.G., Rafiqi, E., Littler, W.A. Eur. Heart J. (1987) [Pubmed]
  20. Pharmacological treatment of insulin resistance at two different stages in the evolution of type 2 diabetes: impact on glucose tolerance and beta-cell function. Xiang, A.H., Peters, R.K., Kjos, S.L., Goico, J., Ochoa, C., Marroquin, A., Tan, S., Hodis, H.N., Azen, S.P., Buchanan, T.A. J. Clin. Endocrinol. Metab. (2004) [Pubmed]
  21. Early intervention with nimodipine in subarachnoid haemorrhage. Neil-Dwyer, G., Mee, E., Dorrance, D., Lowe, D. Eur. Heart J. (1987) [Pubmed]
  22. Importance of heart rate in determining beta-blocker efficacy in acute and long-term acute myocardial infarction intervention trials. Kjekshus, J.K. Am. J. Cardiol. (1986) [Pubmed]
  23. Body temperature in acute myocardial infarction and its relation to early intervention with metoprolol. Herlitz, J., Bengtson, A., Hjalmarson, A., Wilhelmsen, L. International journal of cardiology. (1988) [Pubmed]
  24. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Piyathilake, C.J., Frost, A.R., Manne, U., Bell, W.C., Weiss, H., Heimburger, D.C., Grizzle, W.E. Hum. Pathol. (2000) [Pubmed]
  25. Correlation of methylprednisolone levels in cat spinal cord with its effects on (Na+ + K+)-ATPase, lipid peroxidation, and alpha motor neuron function. Braughler, J.M., Hall, E.D. J. Neurosurg. (1982) [Pubmed]
  26. Altered intracellular expression of the chemokines MIP-1alpha, MIP-1beta and IL-8 by peripheral blood CD4+ and CD8+ T cells in mild allergic asthma. Grob, M., Schmid-Grendelmeier, P., Joller-Jemelka, H.I., Ludwig, E., Dubs, R.W., Grob, P.J., Wüthrich, B., Bisset, L.R. Allergy (2003) [Pubmed]
  27. Potential for misclassification of micronutrient status in children participating in a Head Start program. Droke, E.A., Kennedy, T.S., Hubbs-Tait, L. Journal of the American Dietetic Association. (2006) [Pubmed]
  28. Prevention of oestradiol-associated toxicosis in a dalmatian by early intervention with granulocyte colony-stimulating factor. Suttorp, M., Hoffmann, B., Sippell, W.G. Vet. Rec. (2002) [Pubmed]
  29. Recovery of visual functions in a mouse model of Leber congenital amaurosis. Van Hooser, J.P., Liang, Y., Maeda, T., Kuksa, V., Jang, G.F., He, Y.G., Rieke, F., Fong, H.K., Detwiler, P.B., Palczewski, K. J. Biol. Chem. (2002) [Pubmed]
  30. Untreated initial psychosis: its relation to quality of life and symptom remission in first-episode schizophrenia. Ho, B.C., Andreasen, N.C., Flaum, M., Nopoulos, P., Miller, D. The American journal of psychiatry. (2000) [Pubmed]
  31. Quality of life five years after myocardial infarction. Wiklund, I., Herlitz, J., Hjalmarson, A. Eur. Heart J. (1989) [Pubmed]
  32. High blood glucose concentration is a risk factor for mortality in middle-aged nondiabetic men. 20-year follow-up in the Whitehall Study, the Paris Prospective Study, and the Helsinki Policemen Study. Balkau, B., Shipley, M., Jarrett, R.J., Pyörälä, K., Pyörälä, M., Forhan, A., Eschwège, E. Diabetes Care (1998) [Pubmed]
  33. Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain. Mabbott, N.A., McGovern, G., Jeffrey, M., Bruce, M.E. J. Virol. (2002) [Pubmed]
  34. Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma. Paterson, J.L., Li, Z., Wen, X.Y., Masih-Khan, E., Chang, H., Pollett, J.B., Trudel, S., Stewart, A.K. Br. J. Haematol. (2004) [Pubmed]
  35. Rheumatoid arthritis. New disease-modifying and anti-inflammatory drugs. Infante, R., Lahita, R.G. Geriatrics. (2000) [Pubmed]
  36. Vitamin D receptor: mechanisms for vitamin D resistance in renal failure. Dusso, A.S. Kidney Int. Suppl. (2003) [Pubmed]
  37. Does attention-deficit hyperactivity disorder impact the developmental course of drug and alcohol abuse and dependence? Biederman, J., Wilens, T.E., Mick, E., Faraone, S.V., Spencer, T. Biol. Psychiatry (1998) [Pubmed]
  38. N-(4-hydroxyphenyl)retinamide inhibits retinoblastoma growth through reactive oxygen species-mediated cell death. Tosetti, F., Venè, R., Arena, G., Morini, M., Minghelli, S., Noonan, D.M., Albini, A. Mol. Pharmacol. (2003) [Pubmed]
  39. Effects of early intervention with epoetin alfa on transfusion requirement, hemoglobin level and survival during platinum-based chemotherapy: Results of a multicenter randomised controlled trial. Savonije, J.H., van Groeningen, C.J., van Bochove, A., Honkoop, A.H., van Felius, C.L., Wormhoudt, L.W., Giaccone, G. Eur. J. Cancer (2005) [Pubmed]
  40. Early intervention with short courses of prednisone to prevent progression of asthma in ambulatory patients incompletely responsive to bronchodilators. Harris, J.B., Weinberger, M.M., Nassif, E., Smith, G., Milavetz, G., Stillerman, A. J. Pediatr. (1987) [Pubmed]
  41. The use of anti-IgE in the treatment of allergic asthma. Bush, R.K. Med. Clin. North Am. (2002) [Pubmed]
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