Gene Review:
KLK10 - kallikrein-related peptidase 10
Homo sapiens
Synonyms:
Kallikrein-10, NES1, Normal epithelial cell-specific 1, PRSSL1, Protease serine-like 1
- Overexpression of kallikrein 10 in epithelial ovarian carcinomas. Shvartsman, H.S., Lu, K.H., Lee, J., Lillie, J., Deavers, M.T., Clifford, S., Wolf, J.K., Mills, G.B., Bast, R.C., Gershenson, D.M., Schmandt, R. Gynecol. Oncol. (2003)
- The new human kallikrein gene family: implications in carcinogenesis. Diamandis, E.P., Yousef, G.M., Luo, L.Y., Magklara, A., Obiezu, C.V. Trends Endocrinol. Metab. (2000)
- Expression of the human kallikrein genes 10 (KLK10) and 11 (KLK11) in cancerous and non-cancerous lung tissues. Planque, C., Aïnciburu, M., Heuzé-Vourc'h, N., Régina, S., de Monte, M., Courty, Y. Biol. Chem. (2006)
- Identification of new splice variants and differential expression of the human kallikrein 10 gene, a candidate cancer biomarker. Yousef, G.M., White, N.M., Michael, I.P., Cho, J.C., Robb, J.D., Kurlender, L., Khan, S., Diamandis, E.P. Tumour Biol. (2005)
- Neurobehavioral and neurophysiological observations in six year old children with low lead levels in East and West Germany. Winneke, G., Altmann, L., Krämer, U., Turfeld, M., Behler, R., Gutsmuths, F.J., Mangold, M. Neurotoxicology (1994)
- The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis. Luo, L.Y., Katsaros, D., Scorilas, A., Fracchioli, S., Bellino, R., van Gramberen, M., de Bruijn, H., Henrik, A., Stenman, U.H., Massobrio, M., van der Zee, A.G., Vergote, I., Diamandis, E.P. Cancer Res. (2003)
- CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression. Li, B., Goyal, J., Dhar, S., Dimri, G., Evron, E., Sukumar, S., Wazer, D.E., Band, V. Cancer Res. (2001)
- Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter. Luo, L.Y., Grass, L., Diamandis, E.P. Clin. Chim. Acta (2003)
- Higher expression of human kallikrein 10 in breast cancer tissue predicts tamoxifen resistance. Luo, L.Y., Diamandis, E.P., Look, M.P., Soosaipillai, A.P., Foekens, J.A. Br. J. Cancer (2002)
- The normal epithelial cell-specific 1 (NES1) gene is up-regulated by steroid hormones in the breast carcinoma cell line BT-474. Luo, L.Y., Grass, L., Diamandis, E.P. Anticancer Res. (2000)
- Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers. Bharaj, B.B., Luo, L.Y., Jung, K., Stephan, C., Diamandis, E.P. Prostate (2002)
- Downregulation of human kallikrein 10 (KLK10/NES1) by CpG island hypermethylation in breast, ovarian and prostate cancers. Sidiropoulos, M., Pampalakis, G., Sotiropoulou, G., Katsaros, D., Diamandis, E.P. Tumour Biol. (2005)
- Clinical significance of human kallikrein 10 gene expression in colorectal cancer and gastric cancer. Feng, B., Xu, W.B., Zheng, M.H., Ma, J.J., Cai, Q., Zhang, Y., Ji, J., Lu, A.G., Qu, Y., Li, J.W., Wang, M.L., Hu, W.G., Liu, B.Y., Zhu, Z.G. J. Gastroenterol. Hepatol. (2006)
- Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. Liu, X.L., Wazer, D.E., Watanabe, K., Band, V. Cancer Res. (1996)
- Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues. Luo, L.Y., Grass, L., Howarth, D.J., Thibault, P., Ong, H., Diamandis, E.P. Clin. Chem. (2001)
- Molecular characterization of zyme/protease M/neurosin (PRSS9), a hormonally regulated kallikrein-like serine protease. Yousef, G.M., Luo, L.Y., Scherer, S.W., Sotiropoulou, G., Diamandis, E.P. Genomics (1999)
- In-silico analysis of kallikrein gene expression in pancreatic and colon cancers. Yousef, G.M., Borgoño, C.A., Popalis, C., Yacoub, G.M., Polymeris, M.E., Soosaipillai, A., Diamandis, E.P. Anticancer Res. (2004)
- Structural characterization and mapping of the normal epithelial cell-specific 1 gene. Luo, L., Herbrick, J.A., Scherer, S.W., Beatty, B., Squire, J., Diamandis, E.P. Biochem. Biophys. Res. Commun. (1998)
- Human kallikrein 10 expression in normal tissues by immunohistochemistry. Petraki, C.D., Karavana, V.N., Luo, L.Y., Diamandis, E.P. J. Histochem. Cytochem. (2002)