Gene Review:
RECK - reversion-inducing-cysteine-rich protein...
Homo sapiens
Synonyms:
Reversion-inducing cysteine-rich protein with Kazal motifs, ST15, Suppressor of tumorigenicity 15 protein, hRECK
- Histone deacetylase inhibitor up-regulates RECK to inhibit MMP-2 activation and cancer cell invasion. Liu, L.T., Chang, H.C., Chiang, L.C., Hung, W.C. Cancer Res. (2003)
- The membrane-anchored matrix metalloproteinase (MMP) regulator RECK in combination with MMP-9 serves as an informative prognostic indicator for colorectal cancer. Takeuchi, T., Hisanaga, M., Nagao, M., Ikeda, N., Fujii, H., Koyama, F., Mukogawa, T., Matsumoto, H., Kondo, S., Takahashi, C., Noda, M., Nakajima, Y. Clin. Cancer Res. (2004)
- The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. Oh, J., Takahashi, R., Kondo, S., Mizoguchi, A., Adachi, E., Sasahara, R.M., Nishimura, S., Imamura, Y., Kitayama, H., Alexander, D.B., Ide, C., Horan, T.P., Arakawa, T., Yoshida, H., Nishikawa, S., Itoh, Y., Seiki, M., Itohara, S., Takahashi, C., Noda, M. Cell (2001)
- Tissue inhibitors of metalloproteinase 2 inhibits endothelial cell migration through increased expression of RECK. Oh, J., Seo, D.W., Diaz, T., Wei, B., Ward, Y., Ray, J.M., Morioka, Y., Shi, S., Kitayama, H., Takahashi, C., Noda, M., Stetler-Stevenson, W.G. Cancer Res. (2004)
- RECKing MMP function: implications for cancer development. Rhee, J.S., Coussens, L.M. Trends Cell Biol. (2002)
- Regulation of matrix metalloproteinase-9 and inhibition of tumor invasion by the membrane-anchored glycoprotein RECK. Takahashi, C., Sheng, Z., Horan, T.P., Kitayama, H., Maki, M., Hitomi, K., Kitaura, Y., Takai, S., Sasahara, R.M., Horimoto, A., Ikawa, Y., Ratzkin, B.J., Arakawa, T., Noda, M. Proc. Natl. Acad. Sci. U.S.A. (1998)
- RECK-mediated suppression of tumor cell invasion is regulated by glycosylation in human tumor cell lines. Simizu, S., Takagi, S., Tamura, Y., Osada, H. Cancer Res. (2005)
- RECK expression in pancreatic cancer: its correlation with lower invasiveness and better prognosis. Masui, T., Doi, R., Koshiba, T., Fujimoto, K., Tsuji, S., Nakajima, S., Koizumi, M., Toyoda, E., Tulachan, S., Ito, D., Kami, K., Mori, T., Wada, M., Noda, M., Imamura, M. Clin. Cancer Res. (2003)
- Suppression of matrix metalloproteinase-9 by prostaglandin E(2) in peritoneal macrophage is associated with severity of endometriosis. Wu, M.H., Shoji, Y., Wu, M.C., Chuang, P.C., Lin, C.C., Huang, M.F., Tsai, S.J. Am. J. Pathol. (2005)
- Expression of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) as a prognostic indicator in gastric cancer. Song, S.Y., Son, H.J., Nam, E., Rhee, J.C., Park, C. Eur. J. Cancer (2006)
- HER-2/neu represses the metastasis suppressor RECK via ERK and Sp transcription factors to promote cell invasion. Hsu, M.C., Chang, H.C., Hung, W.C. J. Biol. Chem. (2006)
- TIMP-2 upregulates RECK expression via dephosphorylation of paxillin tyrosine residues 31 and 118. Oh, J., Diaz, T., Wei, B., Chang, H., Noda, M., Stetler-Stevenson, W.G. Oncogene (2006)
- The impact of erythropoietin on hemodialyzer design and performance. Schmidt, B., Ward, R.A. Artificial organs. (1989)
- Silencing of the Metastasis Suppressor RECK by RAS Oncogene Is Mediated by DNA Methyltransferase 3b-Induced Promoter Methylation. Chang, H.C., Cho, C.Y., Hung, W.C. Cancer Res. (2006)
- Expression of a novel matrix metalloproteinase regulator, RECK, and its clinical significance in resected non-small cell lung cancer. Takenaka, K., Ishikawa, S., Kawano, Y., Yanagihara, K., Miyahara, R., Otake, Y., Morioka, Y., Takahashi, C., Noda, M., Wada, H., Tanaka, F. Eur. J. Cancer (2004)
- Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells. Liu, L.T., Chang, H.C., Chiang, L.C., Hung, W.C. Oncogene (2002)
- The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways. Miki, T., Takegami, Y., Okawa, K., Muraguchi, T., Noda, M., Takahashi, C. J. Biol. Chem. (2007)
- The Kazal motifs of RECK protein inhibit MMP-9 secretion and activity and reduce metastasis of lung cancer cells in vitro and in vivo. Chang, C.K., Hung, W.C., Chang, H.C. J. Cell. Mol. Med. (2008)
- Cloning and characterization of a human novel gene C9orf19 encoding a conserved putative protein with an SCP-like extracellular protein domain. Eisenberg, I., Barash, M., Kahan, T., Mitrani-Rosenbaum, S. Gene (2002)
- Correlation of reversion-inducing cysteine-rich protein with kazal motifs (RECK) and extracellular matrix metalloproteinase inducer (EMMPRIN), with MMP-2, MMP-9, and survival in colorectal cancer. van der Jagt, M.F., Sweep, F.C., Waas, E.T., Hendriks, T., Ruers, T.J., Merry, A.H., Wobbes, T., Span, P.N. Cancer Lett. (2006)
- Downregulation of the RECK-tumor and metastasis suppressor gene in glioma invasiveness. Correa, T.C., Brohem, C.A., Winnischofer, S.M., da Silva Cardeal, L.B., Sasahara, R.M., Taboga, S.R., Sogayar, M.C., Maria-Engler, S.S. J. Cell. Biochem. (2006)
- Matrix metalloproteinase inhibitor reversion-inducing cysteine-rich protein with Kazal motifs: a prognostic marker for good clinical outcome in human breast carcinoma. Span, P.N., Sweep, C.G., Manders, P., Beex, L.V., Leppert, D., Lindberg, R.L. Cancer (2003)
- RECK gene expression in hepatocellular carcinoma: correlation with invasion-related clinicopathological factors and its clinical significance. Reverse-inducing--cysteine-rich protein with Kazal motifs. Furumoto, K., Arii, S., Mori, A., Furuyama, H., Gorrin Rivas, M.J., Nakao, T., Isobe, N., Murata, T., Takahashi, C., Noda, M., Imamura, M. Hepatology (2001)