Gene Review:
CRM1 - exportin CRM1
Saccharomyces cerevisiae S288c
Synonyms:
Chromosome region maintenance protein 1, Exportin-1, G8514, KAP124, Karyopherin-124, ...
- Higher order chromosome structure is affected by cold-sensitive mutations in a Schizosaccharomyces pombe gene crm1+ which encodes a 115-kD protein preferentially localized in the nucleus and its periphery. Adachi, Y., Yanagida, M. J. Cell Biol. (1989)
- A role for Ran-GTP and Crm1 in blocking re-replication. Yamaguchi, R., Newport, J. Cell (2003)
- Calcineurin-dependent regulation of Crz1p nuclear export requires Msn5p and a conserved calcineurin docking site. Boustany, L.M., Cyert, M.S. Genes Dev. (2002)
- Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins. Moy, T.I., Silver, P.A. Genes Dev. (1999)
- Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex. Damelin, M., Silver, P.A. Mol. Cell (2000)
- The yeast hnRNP-like protein Hrp1/Nab4 sccumulates in the cytoplasm after hyperosmotic stress: a novel Fps1-dependent response. Henry, M.F., Mandel, D., Routson, V., Henry, P.A. Mol. Biol. Cell (2003)
- The yeast splicing factor Prp40p contains functional leucine-rich nuclear export signals that are essential for splicing. Murphy, M.W., Olson, B.L., Siliciano, P.G. Genetics (2004)
- A Crm1p-independent nuclear export path for the mRNA-associated protein, Npl3p/Mtr13p. Liu, Y., Guo, W., Tartakoff, P.Y., Tartakoff, A.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Class II histone deacetylases confer signal responsiveness to the ankyrin-repeat proteins ANKRA2 and RFXANK. McKinsey, T.A., Kuwahara, K., Bezprozvannaya, S., Olson, E.N. Mol. Biol. Cell (2006)
- CRM1 is responsible for intracellular transport mediated by the nuclear export signal. Fukuda, M., Asano, S., Nakamura, T., Adachi, M., Yoshida, M., Yanagida, M., Nishida, E. Nature (1997)
- Cytoplasmic sequestration of rel proteins by IkappaBalpha requires CRM1-dependent nuclear export. Tam, W.F., Lee, L.H., Davis, L., Sen, R. Mol. Cell. Biol. (2000)
- Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1. Kudo, N., Wolff, B., Sekimoto, T., Schreiner, E.P., Yoneda, Y., Yanagida, M., Horinouchi, S., Yoshida, M. Exp. Cell Res. (1998)
- The NES-Crm1p export pathway is not a major mRNA export route in Saccharomyces cerevisiae. Neville, M., Rosbash, M. EMBO J. (1999)
- Crm1p mediates regulated nuclear export of a yeast AP-1-like transcription factor. Yan, C., Lee, L.H., Davis, L.I. EMBO J. (1998)
- Ltv1 Is Required for Efficient Nuclear Export of the Ribosomal Small Subunit in Saccharomyces cerevisiae. Seiser, R.M., Sundberg, A.E., Wollam, B.J., Zobel-Thropp, P., Baldwin, K., Spector, M.D., Lycan, D.E. Genetics (2006)
- The nuclear exportin Msn5 is required for nuclear export of the Mig1 glucose repressor of Saccharomyces cerevisiae. DeVit, M.J., Johnston, M. Curr. Biol. (1999)
- Molecular cloning of the CRM1 gene from Candida albicans. Raymond, M., Dignard, D., Alarco, A.M., Clark, K.L., Weber, S., Whiteway, M., Leberer, E., Thomas, D.Y. Yeast (2000)
- Crm1-mediated nuclear export of Cdc14 is required for the completion of cytokinesis in budding yeast. Bembenek, J., Kang, J., Kurischko, C., Li, B., Raab, J.R., Belanger, K.D., Luca, F.C., Yu, H. Cell Cycle (2005)
- Structural basis for the assembly of a nuclear export complex. Matsuura, Y., Stewart, M. Nature (2004)
- Yeast poly(A)-binding protein Pab1 shuttles between the nucleus and the cytoplasm and functions in mRNA export. Brune, C., Munchel, S.E., Fischer, N., Podtelejnikov, A.V., Weis, K. RNA (2005)
- The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism. Galani, K., Hurt, E., Simos, G. FEBS Lett. (2005)
- Disruption of the YRB2 gene retards nuclear protein export, causing a profound mitotic delay, and can be rescued by overexpression of XPO1/CRM1. Noguchi, E., Saitoh, Y., Sazer, S., Nishimoto, T. J. Biochem. (1999)
- Fission yeast pap1-dependent transcription is negatively regulated by an essential nuclear protein, crm1. Toda, T., Shimanuki, M., Saka, Y., Yamano, H., Adachi, Y., Shirakawa, M., Kyogoku, Y., Yanagida, M. Mol. Cell. Biol. (1992)