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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Nonlinear Dynamics

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Disease relevance of Nonlinear Dynamics


High impact information on Nonlinear Dynamics

  • These results are integrated into a nonlinear model for mammalian NMD involving alternative routes of entry that converge at a common requirement of UPF1 [3].
  • We investigated the hypothesis by applying a battery of tests originally developed for nonlinear time series analysis and chaos theory to EEG data collected from 32 men who had participated in an ethanol/placebo challenge protocol [4].
  • The growth rate measurements for the air/SF6 and air/CO2 cases are in excellent agreement with the nonlinear model of Sadot et al. coupled with a reduction factor suggested by Rikanati et al [5].
  • This review describes evidence in support of nonlinear models and functional roles of TGF-beta signaling in mediating apoptosis and epithelial-to-mesenchymal transdifferentiation (EMT) in chronic progressive renal disease [6].
  • RESULTS: Deviations from single-hit kinetics were frequently observed in the HTL assays and a nonlinear model was therefore used for analysis [7].

Biological context of Nonlinear Dynamics


Anatomical context of Nonlinear Dynamics


Associations of Nonlinear Dynamics with chemical compounds


Gene context of Nonlinear Dynamics


Analytical, diagnostic and therapeutic context of Nonlinear Dynamics


  1. Heart rate dynamics before spontaneous onset of ventricular fibrillation in patients with healed myocardial infarcts. Mäkikallio, T.H., Koistinen, J., Jordaens, L., Tulppo, M.P., Wood, N., Golosarsky, B., Peng, C.K., Goldberger, A.L., Huikuri, H.V. Am. J. Cardiol. (1999) [Pubmed]
  2. Nonlinear dynamic characteristics of electroencephalography in a high-dose pilocarpine-induced status epilepticus model. Jung, K.Y., Kim, J.M., Kim, D.W. Epilepsy Res. (2003) [Pubmed]
  3. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Gehring, N.H., Kunz, J.B., Neu-Yilik, G., Breit, S., Viegas, M.H., Hentze, M.W., Kulozik, A.E. Mol. Cell (2005) [Pubmed]
  4. Low doses of ethanol reduce evidence for nonlinear structure in brain activity. Ehlers, C.L., Havstad, J., Prichard, D., Theiler, J. J. Neurosci. (1998) [Pubmed]
  5. High-amplitude single-mode perturbation evolution at the Richtmyer-Meshkov instability. Jourdan, G., Houas, L. Phys. Rev. Lett. (2005) [Pubmed]
  6. TGF-beta signaling in renal disease. Böttinger, E.P., Bitzer, M. J. Am. Soc. Nephrol. (2002) [Pubmed]
  7. Limiting dilution analysis of interleukin-2 producing helper T-cell frequencies as a tool in allogeneic hematopoietic cell transplantation. Petersen, S.L., Sidorov, I.A., Russell, C.A., Dickmeiss, E., Vindeløv, L.L. Transplantation (2005) [Pubmed]
  8. Detecting changes in neuronal activities induced by N-methyl-D-aspartate receptor blockade using non-linear dynamics techniques. Aszodi, A., Crunelli, V., Soltesz, I. Neuroscience (1992) [Pubmed]
  9. Ethanol pharmacokinetics in white women: nonlinear model fitting versus zero-order elimination analyses. Mumenthaler, M.S., Taylor, J.L., Yesavage, J.A. Alcohol. Clin. Exp. Res. (2000) [Pubmed]
  10. Nonlinear dynamics in clinical pharmacology: the paradigm of cortisol secretion and suppression. Dokoumetzidis, A., Iliadis, A., Macheras, P. British journal of clinical pharmacology. (2002) [Pubmed]
  11. Propranolol increases the complexity of heart rate fluctuations--a mode of antiarrhythmic action? Lepoluoto, A., Nino, J., Tahvanainen, K., Ylitalo, R., Kuusela, T., Kähönen, M., Kaila, T. International journal of clinical pharmacology and therapeutics. (2005) [Pubmed]
  12. A mechanical model of vocal-fold collision with high spatial and temporal resolution. Gunter, H.E. The Journal of the Acoustical Society of America. (2003) [Pubmed]
  13. Nonlinear models of the first synapse in the light-adapted fly retina. Juusola, M., Weckström, M., Uusitalo, R.O., Korenberg, M.J., French, A.S. J. Neurophysiol. (1995) [Pubmed]
  14. Local Lyapunov exponents detect epileptic zones in spike-less interictal MEG recordings. Kowalik, Z.J., Schnitzler, A., Freund, H., Witte, O.W. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. (2001) [Pubmed]
  15. Pharmacokinetics of 5-fluorouracil and its penetration into pancreatic juice in dogs. Zhu, Z., Fu, Q., Nightingale, C.H., Zhao, Y.P., Liao, Q., Wang, H.N., Xue, C.Q., Yang, Z.Y., Li, D.K. Zhongguo yao li xue bao = Acta pharmacologica Sinica. (1998) [Pubmed]
  16. Quantitative PET studies in pretreated melanoma patients: a comparison of 6-[18F]fluoro-L-dopa with 18F-FDG and (15)O-water using compartment and noncompartment analysis. Dimitrakopoulou-Strauss, A., Strauss, L.G., Burger, C. J. Nucl. Med. (2001) [Pubmed]
  17. Noninvasive quantitative measurement of bacterial growth in porous media under unsaturated-flow conditions. Yarwood, R.R., Rockhold, M.L., Niemet, M.R., Selker, J.S., Bottomley, P.J. Appl. Environ. Microbiol. (2002) [Pubmed]
  18. Single-dose pharmacokinetics of intravenous ampicillin plus sulbactam in healthy elderly and young adult subjects. Rho, J.P., Jones, A., Woo, M., Castle, S., Smith, K., Bawdon, R.E., Norman, D.C. J. Antimicrob. Chemother. (1989) [Pubmed]
  19. Linear versus nonlinear models for hemoglobin adduct formation by acrylamide and its metabolite glycidamide: implications for risk estimation. Calleman, C.J., Stern, L.G., Bergmark, E., Costa, L.G. Cancer Epidemiol. Biomarkers Prev. (1992) [Pubmed]
  20. APOE alleles predict the rate of cognitive decline in Alzheimer disease: a nonlinear model. Martins, C.A., Oulhaj, A., de Jager, C.A., Williams, J.H. Neurology (2005) [Pubmed]
  21. Functional mapping of regional liver asialoglycoprotein receptor amount from single blood sample and SPECT. Shuke, N., Okizaki, A., Kino, S., Sato, J., Ishikawa, Y., Zhao, C., Kinuya, S., Watanabe, N., Yokoyama, K., Aburano, T. J. Nucl. Med. (2003) [Pubmed]
  22. Altered heart rate and blood pressure variability in mice lacking the Mas protooncogene. Walther, T., Wessel, N., Kang, N., Sander, A., Tschöpe, C., Malberg, H., Bader, M., Voss, A. Braz. J. Med. Biol. Res. (2000) [Pubmed]
  23. Dynamic structures of the fructose 6-phosphate/fructose 1,6-bisphosphate cycle in a reconstituted enzyme system. Schellenberger, W., Eschrich, K., Hofmann, E. Biomed. Biochim. Acta (1985) [Pubmed]
  24. Tamoxifen treatment failure in cancer and the nonlinear dynamics of TGFbeta. Turner, S., A Sherratt, J., Cameron, D. J. Theor. Biol. (2004) [Pubmed]
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