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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
MeSH Review

Hospital Charges

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Disease relevance of Hospital Charges

  • For patients having procedural complications (11 complications in 8 patients), surgical procedures, or cardiogenic shock, the mean hospital stay increased to 16.2 days (95% CI, 6.2 to 26.2; P less than 0.05) and the hospital charge increased to $44,400 (95% CI, 24,280 to 64,520; P less than 0.01) [1].
  • CONCLUSION: Methicillin resistance in S. aureus bacteremia is associated with significant increases in length of hospitalization and hospital charges [2].
  • Thus, ICD replacements in the EP laboratory cost less than in the OR due to significantly lower physician fees, hospital charges, and a shorter postprocedural convalescence [3].
  • Cost analyses based on hospital charges suggest that the cost of providing filgrastim therapy can be fully recouped if the drug is used as primary prophylaxis in previously untreated patients, for whom the risk of developing febrile neutropenia is at least 40% [4].

High impact information on Hospital Charges

  • This earlier hematopoietic engraftment after 3.0 micrograms/m2/d IL-1 alpha allowed earlier hospital discharge (median, 25 v 37 days for control or low-dose IL-1 alpha patients [P < .0001]) and a concomitant reduction (by $38,000) in median hospital charges (P = .01) [5].
  • In addition, the use of G-CSF-primed PBPC was associated with a significant reduction in hospital resource utilization, and a reduction in hospital charges [6].
  • The following variables were examined: donor sex, related versus nonrelated donation, operative time, blood loss, length of stay, time out of work, recipient and donor serum creatinine levels, hospital charges, and complications [7].
  • Prophylactic use of octreotide adds more than $75 to the daily hospital charge in the United States. In calendar year 1996, 288 patients received octreotide on the surgical service at the authors' institution, for total billed charges of $74,652 [8].
  • For 187 patients receiving therapy empirically, mean hospital charges for the interval in which the trial antibiotics were used were $3,550 +/- $1,740 for cefotaxime and $3,160 +/- $1,990 for nafcillin and tobramycin [9].

Anatomical context of Hospital Charges


Associations of Hospital Charges with chemical compounds

  • Hospital charges for intracervical PGE2 gel totaled $522 compared with $91 for the insertion of three dilators [11].
  • Uterine tachysystole was significantly more common (70 versus 11%, P < .001) and hospital charges significantly less with misoprostol [12].
  • Patients who received terbutaline by standardized protocol had significantly shorter ICU LOS (3.5 +/- 1.1 vs. 5.0 +/- 2.0 days, P = 0.01), shorter hospital LOS (5.5 +/- 1.3 vs. 8.3 +/- 2.7 days, P < 0.01), and reduced hospital charges ($19,298 +/- $10,516 vs. $26,528 +/- $12,328, P = 0.04) [13].
  • Hospital charges were $21,095 per patient less in the glutamine-supplemented group compared with charges for patients who received standard therapy [14].
  • Total hospital charges for the initial hospitalisation and through 1-year adjusted age for a hypothetical cohort of 100 infants treated with colfosceril palmitate were less than those for a comparable cohort in the air placebo group [15].

Gene context of Hospital Charges

  • Despite similar mean ages and lengths of hospital stay, TPA patients had had significantly higher total hospital charges and ancillary charges than had had concurrent MI patients who had not received TPA (p less than 0.0001) [16].
  • MRSA bacteremia had a median attributable length of stay of 2 days and a median attributable hospital charge of 6916 dollars [2].
  • RESULTS: Patients receiving at least one ABO-mismatched pool of platelets had a significantly longer hospital stay, more days of fever, greater total hospital charges, and more RBC transfusions [17].
  • The costs for surgical procedures, IVF treatment, medication, complications, management of pregnancy and delivery as well as of early pregnancy losses were calculated from standardized hospital charges [18].
  • The charts and hospital charges for 102 patients undergoing secundum ASD or sinus venosus defect surgery between March 1992 and July 1994 were reviewed; 36 patients (Group I) had surgery prior to introduction of the CPG, and 66 patients were managed according to the CPG [19].

Analytical, diagnostic and therapeutic context of Hospital Charges

  • CONCLUSIONS: All patients made functional improvement after inpatient rehabilitation, but women and patients 85 years and older had longer LOS and lower FIM efficiency, incurred greater hospital charges, and were less likely to be discharged to home than men and younger counterparts [20].
  • The hospital charges for all craniotomies and transsphenoidal procedures were gathered for a 4-year period from a single, non-profit hospital serving San Diego. Calif., USA [21].


  1. Percutaneous aortic balloon valvuloplasty in octogenarians: morbidity and mortality. Brady, S.T., Davis, C.A., Kussmaul, W.G., Laskey, W.K., Hirshfeld, J.W., Herrmann, H.C. Ann. Intern. Med. (1989) [Pubmed]
  2. The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges. Cosgrove, S.E., Qi, Y., Kaye, K.S., Harbarth, S., Karchmer, A.W., Carmeli, Y. Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America. (2005) [Pubmed]
  3. Replacing abdominally implanted defibrillators: effect of procedure setting on cost. Vorperian, V.R., Lawrence, S., Chlebowski, K. Pacing and clinical electrophysiology : PACE. (1999) [Pubmed]
  4. Filgrastim. A reappraisal of pharmacoeconomic considerations in the prophylaxis and treatment of chemotherapy-induced neutropenia. Frampton, J.E., Faulds, D. PharmacoEconomics. (1996) [Pubmed]
  5. Interleukin-1 alpha administered after autologous transplantation: a phase I/II clinical trial. Weisdorf, D., Katsanis, E., Verfaillie, C., Ramsay, N.K., Haake, R., Garrison, L., Blazar, B.R. Blood (1994) [Pubmed]
  6. Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Peters, W.P., Rosner, G., Ross, M., Vredenburgh, J., Meisenberg, B., Gilbert, C., Kurtzberg, J. Blood (1993) [Pubmed]
  7. Laparoscopic donor nephrectomy with a 23-hour stay: a new standard for transplantation surgery. Kuo, P.C., Johnson, L.B., Sitzmann, J.V. Ann. Surg. (2000) [Pubmed]
  8. Does prophylactic octreotide decrease the rates of pancreatic fistula and other complications after pancreaticoduodenectomy? Results of a prospective randomized placebo-controlled trial. Yeo, C.J., Cameron, J.L., Lillemoe, K.D., Sauter, P.K., Coleman, J., Sohn, T.A., Campbell, K.A., Choti, M.A. Ann. Surg. (2000) [Pubmed]
  9. Cefotaxime vs nafcillin and tobramycin for the treatment of serious infection. Comparative cost-effectiveness. Moore, R.D., Smith, C.R., Holloway, J.J., Lietman, P.S. Arch. Intern. Med. (1986) [Pubmed]
  10. Comparison of microscopic epididymal sperm aspiration and intracytoplasmic sperm injection/in-vitro fertilization with repeat microscopic reconstruction following vasectomy: is second attempt vas reversal worth the effort? Donovan, J.F., DiBaise, M., Sparks, A.E., Kessler, J., Sandlow, J.I. Hum. Reprod. (1998) [Pubmed]
  11. Pre-induction cervical ripening: a randomized comparison of two methods. Krammer, J., Williams, M.C., Sawai, S.K., O'Brien, W.F. Obstetrics and gynecology. (1995) [Pubmed]
  12. A randomized trial of misoprostol and oxytocin for induction of labor: safety and efficacy. Kramer, R.L., Gilson, G.J., Morrison, D.S., Martin, D., Gonzales, J.L., Qualls, C.R. Obstetrics and gynecology. (1997) [Pubmed]
  13. Protocol-based titration of intravenous terbutaline decreases length of stay in pediatric status asthmaticus. Carroll, C.L., Schramm, C.M. Pediatr. Pulmonol. (2006) [Pubmed]
  14. A cost-evaluation of glutamine-supplemented parenteral nutrition in adult bone marrow transplant patients. MacBurney, M., Young, L.S., Ziegler, T.R., Wilmore, D.W. Journal of the American Dietetic Association. (1994) [Pubmed]
  15. Economic outcomes of colfosceril palmitate rescue therapy in infants weighing 1250g or more with respiratory distress syndrome: results from a randomised trial. Backhouse, M.E., Mauskopf, J.A., Jones, D., Wold, D.E., Schumacher, R., Cotton, R., Long, W.A. PharmacoEconomics. (1994) [Pubmed]
  16. Community hospital experience with recombinant tissue plasminogen activator in acute myocardial infarction. Austin, S.M., Caro, M., Gemmel, D. Journal of general internal medicine : official journal of the Society for Research and Education in Primary Care Internal Medicine. (1992) [Pubmed]
  17. Association of ABO-mismatched platelet transfusions with morbidity and mortality in cardiac surgery. Blumberg, N., Heal, J.M., Hicks, G.L., Risher, W.H. Transfusion (2001) [Pubmed]
  18. Cost--effectiveness analysis of salpingectomy prior to IVF, based on a randomized controlled trial. Strandell, A., Lindhard, A., Eckerlund, I. Hum. Reprod. (2005) [Pubmed]
  19. Tracheal extubation of children in the operating room after atrial septal defect repair as part of a clinical practice guideline. Laussen, P.C., Reid, R.W., Stene, R.A., Pare, D.S., Hickey, P.R., Jonas, R.A., Freed, M.D. Anesth. Analg. (1996) [Pubmed]
  20. Sex and age effects on outcomes of total hip arthroplasty after inpatient rehabilitation. Vincent, H.K., Alfano, A.P., Lee, L., Vincent, K.R. Archives of physical medicine and rehabilitation. (2006) [Pubmed]
  21. A comparison of craniotomy and Gamma Knife charges in a community-based Gamma Knife Center. Ott, K. Stereotactic and functional neurosurgery. (1996) [Pubmed]
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