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MeSH Review

Weibel-Palade Bodies

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Disease relevance of Weibel-Palade Bodies


High impact information on Weibel-Palade Bodies


Biological context of Weibel-Palade Bodies


Anatomical context of Weibel-Palade Bodies


Associations of Weibel-Palade Bodies with chemical compounds


Gene context of Weibel-Palade Bodies


Analytical, diagnostic and therapeutic context of Weibel-Palade Bodies


  1. Sphingosine 1-phosphate activates Weibel-Palade body exocytosis. Matsushita, K., Morrell, C.N., Lowenstein, C.J. Proc. Natl. Acad. Sci. U.S.A. (2004) [Pubmed]
  2. Rickettsia rickettsii infection of cultured endothelial cells induces release of large von Willebrand factor multimers from Weibel-Palade bodies. Sporn, L.A., Shi, R.J., Lawrence, S.O., Silverman, D.J., Marder, V.J. Blood (1991) [Pubmed]
  3. Inducible secretion of large, biologically potent von Willebrand factor multimers. Sporn, L.A., Marder, V.J., Wagner, D.D. Cell (1986) [Pubmed]
  4. Angiopoietin-2 sensitizes endothelial cells to TNF-alpha and has a crucial role in the induction of inflammation. Fiedler, U., Reiss, Y., Scharpfenecker, M., Grunow, V., Koidl, S., Thurston, G., Gale, N.W., Witzenrath, M., Rosseau, S., Suttorp, N., Sobke, A., Herrmann, M., Preissner, K.T., Vajkoczy, P., Augustin, H.G. Nat. Med. (2006) [Pubmed]
  5. Rapid secretion of prestored interleukin 8 from Weibel-Palade bodies of microvascular endothelial cells. Utgaard, J.O., Jahnsen, F.L., Bakka, A., Brandtzaeg, P., Haraldsen, G. J. Exp. Med. (1998) [Pubmed]
  6. Interleukin 4 or oncostatin M induces a prolonged increase in P-selectin mRNA and protein in human endothelial cells. Yao, L., Pan, J., Setiadi, H., Patel, K.D., McEver, R.P. J. Exp. Med. (1996) [Pubmed]
  7. Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. Pinsky, D.J., Naka, Y., Liao, H., Oz, M.C., Wagner, D.D., Mayadas, T.N., Johnson, R.C., Hynes, R.O., Heath, M., Lawson, C.A., Stern, D.M. J. Clin. Invest. (1996) [Pubmed]
  8. Localization of alpha 1,3-fucosyltransferase VI in Weibel-Palade bodies of human endothelial cells. Schnyder-Candrian, S., Borsig, L., Moser, R., Berger, E.G. Proc. Natl. Acad. Sci. U.S.A. (2000) [Pubmed]
  9. Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin. Williams, R., Schlüter, T., Roberts, M.S., Knauth, P., Bohnensack, R., Cutler, D.F. Mol. Biol. Cell (2004) [Pubmed]
  10. Weibel-Palade body membrane proteins exhibit differential trafficking after exocytosis in endothelial cells. Arribas, M., Cutler, D.F. Traffic (2000) [Pubmed]
  11. Inhibition of protein tyrosine phosphatases suppresses P-selectin exocytosis in activated human platelets. Chen, M., Geng, J.G. Biochem. Biophys. Res. Commun. (2001) [Pubmed]
  12. Biogenesis of von Willebrand factor-containing organelles in heterologous transfected CV-1 cells. Voorberg, J., Fontijn, R., Calafat, J., Janssen, H., van Mourik, J.A., Pannekoek, H. EMBO J. (1993) [Pubmed]
  13. Activated platelets induce Weibel-Palade-body secretion and leukocyte rolling in vivo: role of P-selectin. Dole, V.S., Bergmeier, W., Mitchell, H.A., Eichenberger, S.C., Wagner, D.D. Blood (2005) [Pubmed]
  14. von Willebrand factor proteolytic processing and multimerization precede the formation of Weibel-Palade bodies. Vischer, U.M., Wagner, D.D. Blood (1994) [Pubmed]
  15. In vitro reconstruction of a human capillary-like network in a tissue-engineered skin equivalent. Black, A.F., Berthod, F., L'heureux, N., Germain, L., Auger, F.A. FASEB J. (1998) [Pubmed]
  16. Divergent fates of P- and E-selectins after their expression on the plasma membrane. Subramaniam, M., Koedam, J.A., Wagner, D.D. Mol. Biol. Cell (1993) [Pubmed]
  17. Control of proliferation of human vascular endothelial cells. Characterization of the response of human umbilical vein endothelial cells to fibroblast growth factor, epidermal growth factor, and thrombin. Gospodarowicz, D., Brown, K.D., Birdwell, C.R., Zetter, B.R. J. Cell Biol. (1978) [Pubmed]
  18. Relationship between human development and disappearance of unusually large von Willebrand factor multimers from plasma. Katz, J.A., Moake, J.L., McPherson, P.D., Weinstein, M.J., Moise, K.J., Carpenter, R.J., Sala, D.J. Blood (1989) [Pubmed]
  19. Desmopressin induces endothelial P-selectin expression and leukocyte rolling in postcapillary venules. Kanwar, S., Woodman, R.C., Poon, M.C., Murohara, T., Lefer, A.M., Davenpeck, K.L., Kubes, P. Blood (1995) [Pubmed]
  20. The endothelial cells of large and small blood vessels. Zetter, B.R. Diabetes (1981) [Pubmed]
  21. The tetraspanin CD63/lamp3 cycles between endocytic and secretory compartments in human endothelial cells. Kobayashi, T., Vischer, U.M., Rosnoblet, C., Lebrand, C., Lindsay, M., Parton, R.G., Kruithof, E.K., Gruenberg, J. Mol. Biol. Cell (2000) [Pubmed]
  22. Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells. Knop, M., Aareskjold, E., Bode, G., Gerke, V. EMBO J. (2004) [Pubmed]
  23. CD63 is a component of Weibel-Palade bodies of human endothelial cells. Vischer, U.M., Wagner, D.D. Blood (1993) [Pubmed]
  24. Human endothelial cell storage granules: a novel intracellular site for isoforms of the endothelin-converting enzyme. Russell, F.D., Skepper, J.N., Davenport, A.P. Circ. Res. (1998) [Pubmed]
  25. The Tie-2 ligand angiopoietin-2 is stored in and rapidly released upon stimulation from endothelial cell Weibel-Palade bodies. Fiedler, U., Scharpfenecker, M., Koidl, S., Hegen, A., Grunow, V., Schmidt, J.M., Kriz, W., Thurston, G., Augustin, H.G. Blood (2004) [Pubmed]
  26. P38 MAPK: critical molecule in thrombin-induced NF-kappa B-dependent leukocyte recruitment. Kaur, J., Woodman, R.C., Kubes, P. Am. J. Physiol. Heart Circ. Physiol. (2003) [Pubmed]
  27. Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP. Cleator, J.H., Zhu, W.Q., Vaughan, D.E., Hamm, H.E. Blood (2006) [Pubmed]
  28. PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells. Bonfanti, R., Furie, B.C., Furie, B., Wagner, D.D. Blood (1989) [Pubmed]
  29. Intracellular localization of factor VIII-related antigen and fibronectin in cultured human endothelial cells: evidence for divergent routes of intracellular translocation. Hormia, M., Lehto, V.P., Virtanen, I. Eur. J. Cell Biol. (1984) [Pubmed]
  30. Epithelioid hemangioendothelioma of the liver: report of two cases. Fedeli, G., Certo, M., Cannizzaro, O., Forti, G., Gimbo, G., Abagnale, R., Vecchio, F.M. The Italian journal of gastroenterology. (1991) [Pubmed]
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