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Rickettsia rickettsii

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Disease relevance of Rickettsia rickettsii


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Chemical compound and disease context of Rickettsia rickettsii


Biological context of Rickettsia rickettsii


Anatomical context of Rickettsia rickettsii


Gene context of Rickettsia rickettsii


Analytical, diagnostic and therapeutic context of Rickettsia rickettsii


  1. Efficacy of doxycycline, azithromycin, or trovafloxacin for treatment of experimental Rocky Mountain spotted fever in dogs. Breitschwerdt, E.B., Papich, M.G., Hegarty, B.C., Gilger, B., Hancock, S.I., Davidson, M.G. Antimicrob. Agents Chemother. (1999) [Pubmed]
  2. In vitro susceptibilities of Coxiella burnetii, Rickettsia rickettsii, and Rickettsia conorii to the fluoroquinolone sparfloxacin. Raoult, D., Bres, P., Drancourt, M., Vestris, G. Antimicrob. Agents Chemother. (1991) [Pubmed]
  3. Penicillin-induced unstable intracellular formation of spheroplasts by rickettsiae. Wisseman, C.L., Silverman, D.J., Waddell, A., Brown, D.T. J. Infect. Dis. (1982) [Pubmed]
  4. Indirect hemagglutination test for human antibody to typhus and spotted fever group rickettsiae. Shirai, A., Dietel, J.W., Osterman, J.V. J. Clin. Microbiol. (1975) [Pubmed]
  5. Analysis of Leptospira spp., Leptonema illini, and Rickettsia rickettsii for the 39-kilodalton antigen (P39) of Borrelia burgdorferi. Schwan, T.G., Schrumpf, M.E., Gage, K.L., Gilmore, R.D. J. Clin. Microbiol. (1992) [Pubmed]
  6. Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression. Rydkina, E., Sahni, A., Silverman, D.J., Sahni, S.K. Infect. Immun. (2002) [Pubmed]
  7. NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection. Clifton, D.R., Goss, R.A., Sahni, S.K., van Antwerp, D., Baggs, R.B., Marder, V.J., Silverman, D.J., Sporn, L.A. Proc. Natl. Acad. Sci. U.S.A. (1998) [Pubmed]
  8. Tissue factor mRNA expression in the endothelium of an intact umbilical vein. Courtney, M.A., Haidaris, P.J., Marder, V.J., Sporn, L.A. Blood (1996) [Pubmed]
  9. Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response. Rydkina, E., Silverman, D.J., Sahni, S.K. Cell. Microbiol. (2005) [Pubmed]
  10. NF-kappaB activation during Rickettsia rickettsii infection of endothelial cells involves the activation of catalytic IkappaB kinases IKKalpha and IKKbeta and phosphorylation-proteolysis of the inhibitor protein IkappaBalpha. Clifton, D.R., Rydkina, E., Freeman, R.S., Sahni, S.K. Infect. Immun. (2005) [Pubmed]
  11. A Rickettsia WASP-like protein activates the Arp2/3 complex and mediates actin-based motility. Jeng, R.L., Goley, E.D., D'Alessio, J.A., Chaga, O.Y., Svitkina, T.M., Borisy, G.G., Heinzen, R.A., Welch, M.D. Cell. Microbiol. (2004) [Pubmed]
  12. In vitro sensitivity of Rickettsia rickettsii to doxycycline. Wisseman, C.L., Waddell, A. J. Infect. Dis. (1982) [Pubmed]
  13. Heparin protects human endothelial cells infected by Rickettsia rickettsii. Silverman, D.J., Santucci, L.A., Sekeyova, Z. Infect. Immun. (1991) [Pubmed]
  14. Prednisolone at anti-inflammatory or immunosuppressive dosages in conjunction with doxycycline does not potentiate the severity of Rickettsia rickettsii infection in dogs. Breitschwerdt, E.B., Davidson, M.G., Hegarty, B.C., Papich, M.G., Grindem, C.B. Antimicrob. Agents Chemother. (1997) [Pubmed]
  15. Reactogenicity, immunogenicity, and efficacy of a chick embryo cell-derived vaccine for Rocky Mountain spotted fever. Clements, M.L., Wisseman, C.L., Woodward, T.E., Fiset, P., Dumler, J.S., McNamee, W., Black, R.E., Rooney, J., Hughes, T.P., Levine, M.M. J. Infect. Dis. (1983) [Pubmed]
  16. In vitro guinea pig leukocyte reactions to Rickettsia rickettsii. Kenyon, R.H., Ascher, M.S., Kishimoto, R.A., Pedersen, C.E. Infect. Immun. (1977) [Pubmed]
  17. Nucleotide sequence of polymerase chain reaction product amplified from Rickettsia japonica DNA using Rickettsia rickettsii 190-kilodalton surface antigen gene primers. Yan, Y., Uchiyama, T., Uchida, T. Microbiol. Immunol. (1994) [Pubmed]
  18. False-positive results in serologic tests for Rocky Mountain spotted fever during pregnancy. Welch, K.J., Rumley, R.L., Levine, J.A. South. Med. J. (1991) [Pubmed]
  19. Initial clinical evaluation of a new Rocky Mountain spotted fever vaccine of tissue culture origin. Ascher, M.S., Oster, C.N., Harber, P.I., Kenyon, R.H., Pedersen, C.E. J. Infect. Dis. (1978) [Pubmed]
  20. Hemocytic rickettsia-like organisms in ticks: serologic reactivity with antisera to Ehrlichiae and detection of DNA of agent of human granulocytic ehrlichiosis by PCR. Magnarelli, L.A., Stafford, K.C., Mather, T.N., Yeh, M.T., Horn, K.D., Dumler, J.S. J. Clin. Microbiol. (1995) [Pubmed]
  21. Effects of ectopically expressed neuronal Wiskott-Aldrich syndrome protein domains on Rickettsia rickettsii actin-based motility. Harlander, R.S., Way, M., Ren, Q., Howe, D., Grieshaber, S.S., Heinzen, R.A. Infect. Immun. (2003) [Pubmed]
  22. Molecular and functional analysis of the lepB gene, encoding a type I signal peptidase from Rickettsia rickettsii and Rickettsia typhi. Rahman, M.S., Simser, J.A., Macaluso, K.R., Azad, A.F. J. Bacteriol. (2003) [Pubmed]
  23. Increased expression of plasminogen activator inhibitor-1 in R. rickettsii-infected endothelial cells. Shi, R.J., Simpson-Haidaris, P.J., Marder, V.J., Silverman, D.J., Sporn, L.A. Thromb. Haemost. (1996) [Pubmed]
  24. Superoxide dismutase-dependent, catalase-sensitive peroxides in human endothelial cells infected by Rickettsia rickettsii. Hong, J.E., Santucci, L.A., Tian, X., Silverman, D.J. Infect. Immun. (1998) [Pubmed]
  25. Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by Rickettsia conorii- and Rickettsia rickettsii-infected cultured endothelial cells. Drancourt, M., Alessi, M.C., Levy, P.Y., Juhan-Vague, I., Raoult, D. Infect. Immun. (1990) [Pubmed]
  26. Identification of Rickettsia rickettsii in formalin-fixed, paraffin-embedded tissues by immunofluorescence. Hall, W.C., Bagley, L.R. J. Clin. Microbiol. (1978) [Pubmed]
  27. Evaluation of immunoperoxidase techniques to detect Rickettsia rickettsii in fixed tissue sections. White, W.L., Patrick, J.D., Miller, L.R. Am. J. Clin. Pathol. (1994) [Pubmed]
  28. Detection of Rocky Mountain spotted fever antibodies by a latex agglutination test. Hechemy, K.E., Anacker, R.L., Philip, R.N., Kleeman, K.T., MacCormack, J.N., Sasowski, S.J., Michaelson, E.E. J. Clin. Microbiol. (1980) [Pubmed]
  29. Detection of Rickettsia rickettsii antibodies in human sera by crossed immunoelectrophoresis. Anacker, R.L., Philip, R.N., Wilfert, C.M., Kleeman, K.T., Turner, L., MacCormack, J.N., Hechemy, K.E. J. Clin. Microbiol. (1983) [Pubmed]
  30. Evaluation of a Western blot method for the detection of Yersinia Antibodies: evidence of serological cross-reactivity between Yersinia outer membrane proteins and Borrelia burgdorferi. Rawlins, M.L., Gerstner, C., Hill, H.R., Litwin, C.M. Clin. Diagn. Lab. Immunol. (2005) [Pubmed]
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