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MeSH Review

Headache Disorders

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Disease relevance of Headache Disorders


Psychiatry related information on Headache Disorders


High impact information on Headache Disorders

  • The efficacy of inhibitors of NOS has not been tested in patients with tension-type chronic headache [8].
  • Nerve growth factor (NGF) levels were determined in the CSF of patients with chronic daily headache (CDH) and correlated with levels of sensory neuropeptides [9].
  • These headache syndromes have been shown to respond to melatonin and lithium therapy, both of which have an indirect impact on the sleep-wake cycle [10].
  • The medication, which contained butalbital, was self-administered in escalating doses for the treatment of chronic headaches [11].
  • It was hypothesized that chronic headache patients (n = 83) would be characterized not so much by exposure to a continued surfeit of inherently major life events as by a tendency to appraise cognitively and emotionally any ongoing microstressor or daily hassle as being more arousing or impactful than headache-free controls (n = 51) [12].

Chemical compound and disease context of Headache Disorders


Biological context of Headache Disorders

  • An alteration in serotonin concentration has been found in patients with chronic headache caused by abuse of analgesic substances as well as an up-regulation of 5HT2 platelet receptors, which has been correlated with chronicization of the headache [18].
  • To investigate the relative frequency, clinical characteristics, and associated features of primary chronic daily headache in Omani patients, 171 patients visiting the Neurology Clinic at Sultan Qaboos University Hospital were evaluated [19].

Anatomical context of Headache Disorders


Gene context of Headache Disorders


Analytical, diagnostic and therapeutic context of Headache Disorders


  1. Chronic paroxysmal hemicrania: a disabling headache syndrome responding to indomethacin. Price, R.W., Posner, J.B. Ann. Neurol. (1978) [Pubmed]
  2. Evolution of the measurement of quality of life in migraine. Solomon, G.D. Neurology (1997) [Pubmed]
  3. Idiopathic intracranial hypertension without papilledema: a case-control study in a headache center. Wang, S.J., Silberstein, S.D., Patterson, S., Young, W.B. Neurology (1998) [Pubmed]
  4. Scaling the affective domain of pain: a study of the dimensionality of verbal descriptors. Morley, S., Pallin, V. Pain (1995) [Pubmed]
  5. Analgesic effect of octreotide in headache associated with acromegaly is not mediated by opioid mechanisms. Case report. Pascual, J., Freijanes, J., Berciano, J., Pesquera, C. Pain (1991) [Pubmed]
  6. Paroxetine. An update of its pharmacology and therapeutic use in depression and a review of its use in other disorders. Gunasekara, N.S., Noble, S., Benfield, P. Drugs (1998) [Pubmed]
  7. Personality characteristics and accompanying symptoms in temporomandibular joint dysfunction, headache, and facial pain. Mongini, F., Ciccone, G., Ibertis, F., Negro, C. Journal of orofacial pain. (2000) [Pubmed]
  8. Effect of inhibition of nitric oxide synthase on chronic tension-type headache: a randomised crossover trial. Ashina, M., Lassen, L.H., Bendtsen, L., Jensen, R., Olesen, J. Lancet (1999) [Pubmed]
  9. Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients. Sarchielli, P., Alberti, A., Floridi, A., Gallai, V. Neurology (2001) [Pubmed]
  10. Rare nocturnal headaches. Cohen, A.S., Kaube, H. Curr. Opin. Neurol. (2004) [Pubmed]
  11. Barbiturate withdrawal following Internet purchase of Fioricet. Romero, C.E., Baron, J.D., Knox, A.P., Hinchey, J.A., Ropper, A.H. Arch. Neurol. (2004) [Pubmed]
  12. The role of stressful life events in the persistence of primary headache: major events vs. daily hassles. De Benedittis, G., Lorenzetti, A. Pain (1992) [Pubmed]
  13. Trazodone and intractable headaches. Pies, R. The Journal of clinical psychiatry. (1983) [Pubmed]
  14. Valproate in intractable headache. Mathew, N.T. Cephalalgia : an international journal of headache. (1994) [Pubmed]
  15. A differential response to treatment with divalproex sodium in patients with intractable headache. Rothrock, J.F., Kelly, N.M., Brody, M.L., Golbeck, A. Cephalalgia : an international journal of headache. (1994) [Pubmed]
  16. Reduced serotonin vascular sensitivity in ergotamine abusers. Panconesi, A., Franchi, G., Del Bianco, P.L., Anselmi, B., Andreini, R., Sicuteri, F. Cephalalgia : an international journal of headache. (1989) [Pubmed]
  17. Histamine-free diet: treatment of choice for histamine-induced food intolerance and supporting treatment for chronic headaches. Wantke, F., Götz, M., Jarisch, R. Clin. Exp. Allergy (1993) [Pubmed]
  18. Nitric oxide pathway, Ca2+, and serotonin content in platelets from patients suffering from chronic daily headache. Sarchielli, P., Alberti, A., Russo, S., Codini, M., Panico, R., Floridi, A., Gallai, V. Cephalalgia : an international journal of headache. (1999) [Pubmed]
  19. Primary chronic daily headache: clinical and pharmacological aspects. A clinic-based study in Oman. Deleu, D., Hanssens, Y. Headache. (1999) [Pubmed]
  20. Glutamate and nitric oxide pathway in chronic daily headache: evidence from cerebrospinal fluid. Gallai, V., Alberti, A., Gallai, B., Coppola, F., Floridi, A., Sarchielli, P. Cephalalgia : an international journal of headache. (2003) [Pubmed]
  21. Headache response to glyceryl trinitrate in patients with and without obstructive coronary artery disease. Hsi, D.H., Roshandel, A., Singh, N., Szombathy, T., Meszaros, Z.S. Heart (2005) [Pubmed]
  22. Wine and headache. Jarisch, R., Wantke, F. Int. Arch. Allergy Immunol. (1996) [Pubmed]
  23. The effects of moclobemide on the pharmacokinetics of the 5-HT1B/1D agonist rizatriptan in healthy volunteers. Van Haarst, A.D., Van Gerven, J.M., Cohen, A.F., De Smet, M., Sterrett, A., Birk, K.L., Fisher, A.L., De Puy, M.E., Goldberg, M.R., Musson, D.G. British journal of clinical pharmacology. (1999) [Pubmed]
  24. Is serotonin hyperalgesic or analgesic? Sommer, C. Current pain and headache reports. (2006) [Pubmed]
  25. Provision of 24 hour acute neurology care by neurologists: manpower requirements in the UK. Carroll, C., Zajicek, J. J. Neurol. Neurosurg. Psychiatr. (2004) [Pubmed]
  26. Antimigraine drugs in the management of daily chronic headaches: clinical profiles of responsive patients. Micieli, G., Piazza, D., Sinforiani, E., Cavallini, A., Trucco, M., Gabellini, S., Mancuso, A., Pacchetti, C. Cephalalgia : an international journal of headache. (1985) [Pubmed]
  27. Paroxetine in the treatment of chronic daily headache. Foster, C.A., Bafaloukos, J. Headache. (1994) [Pubmed]
  28. Death by managed care-denial of hospitalization for headache. Young, W.B. Headache. (1999) [Pubmed]
  29. The role of occlusal adjustment in the management of temporomandibular disorders. Kirveskari, P. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. (1997) [Pubmed]
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