Disease relevance of Gastroepiploic Artery

• In the present study, we investigated the effect of lipoteichoic acid (LTA) from the cell wall of Staphylococcus aureus on contractions elicited by norepinephrine (NE) in rings cut from human gastroepiploic arteries [1].
• Spontaneous rupture of a left gastroepiploic artery aneurysm in a patient with autosomal-dominant polycystic kidney disease [2].
• Middle colic artery-gastroepiploic artery bypass for compromised collateral flow in distal pancreatectomy with celiac artery resection [3].

High impact information on Gastroepiploic Artery

• CONCLUSIONS: Gastroepiploic artery grafts implanted long-term are more reactive than grafted coronary arteries to ergometrine and nitrates [4].
• The radial and the gastroepiploic arteries with endothelium presented a higher contraction force than the internal mammary artery in response to norepinephrine and serotonin [5].
• The gastroepiploic artery had a lower sensitivity to thromboxane A2 mimetic than the two other vessels [5].
• In contrast, bradykinin induced potent relaxations in rings of the gastroepiploic artery but not in rings of the left internal mammary artery [6].
• This study describes the efficacy of the right gastroepiploic artery (GEA) as graft material for coronary artery bypass grafting (CABG) as assessed by exercise thallium 201 myocardial scintigraphy in eight patients (age, 59.4 +/- 9.35 years [mean +/- SD]) who underwent CABG with the GEA graft in the past 2 years [7].

Biological context of Gastroepiploic Artery

• Neurogenic double-peaked vasoconstriction of human gastroepiploic artery is mediated by both alpha1- and alpha2-adrenoceptors [8].

Anatomical context of Gastroepiploic Artery

• METHODS: Gastroepiploic artery and saphenous vein rings were mounted in an organ bath containing Krebs-Ringer bicarbonate solution aerated with 95% O2 and 5% CO2 at 37 degrees C. Endothelium dependent responses of acetylcholine, histamine, and bradykinin were examined on the precontracted rings of the vessels [9].
• RESULTS: (1) Renin activity in human gastroepiploic arteries with endothelium was significantly higher than in those without endothelium; (2) immunoreactive staining selectively occurred in the endothelial cells of human gastroepiploic arteries [10].
• Isolated human gastroepiploic vein tributaries responded to dopamine only with contractions, whereas the gastroepiploic artery branches in the same region of the omentum responded with relaxations [11].
• In stomachs infused exclusively by the right gastroepiploic artery, i.e. following ligation of all other gastric vessels on the stomach wall, both methods produced good fundal filling, while demonstrating consistently poor filling of a strip of stomach wall along the lesser curve [12].
• Comparison of prostacyclin production of human gastroepiploic artery and saphenous vein [13].

Associations of Gastroepiploic Artery with chemical compounds

• It may be concluded that relaxation of mesenteric and gastroepiploic arteries induced by histamine is mainly associated with the release of prostaglandin I2 from the arterial wall, which results from an activation of histaminergic H1 receptors [14].
• 1. This study describes attempts to compare prostacyclin (IP-) receptors in human, pig, horse, rabbit and rat platelets and in circular muscle of human, rabbit and dog mesenteric and pig gastroepiploic arteries [15].
• 1. The contribution of postjunctional P2X receptors and subtypes of alpha-adrenoceptors to vasoconstrictor responses following periarterial electrical nerve stimulation (PNS, 30 s trains of pulses at a frequency of 2, 4 or 8 Hz) was investigated in human gastroepiploic arteries [8].
• In helical strips of dog mesenteric and gastroepiploic arteries contracted with prostaglandin (PG) F2 alpha, the addition of histamine (10(-6) M) caused a relaxation, which was markedly attenuated by treatment with aspirin, indomethacin or tranylcypromine [14].
• Relaxations of mesenteric and gastroepiploic arteries induced by histamine were markedly attenuated or abolished by combined treatment with chlorpheniramine and cimetidine [14].

Gene context of Gastroepiploic Artery

• RT-PCR using PDE3A- or PDE3B-specific oligonucleotide primer demonstrated the existence of PDE3A sequence in the gastroepiploic artery [16].
• HR720 inhibited the Ang II-induced contraction of isolated rabbit aortic strips and human gastroepiploic arteries in a noncompetitive manner, pD'2=9.40 and 9.62 for rabbit aorta and human artery, respectively [17].
• Enhanced secretion of tissue plasminogen activator by simultaneous use of retinoic acid and ascorbic acid from tissue cultured gastroepiploic artery [18].
• Experiments in calves and pigs with CCK-8 infusions into the duodenal branches of the right gastroepiploic artery confirmed the results of luminal CCK-8 and questioned the physiological relevance of a direct mechanism of CCK on the pancreatic acini [19].
• DESIGN: Biochemical and immunohistochemical procedures were adopted to examine the existence of renin in human gastroepiploic arteries using an antibody raised against human recombinant renin or a specific renin inhibitor [10].

Analytical, diagnostic and therapeutic context of Gastroepiploic Artery

• Out of 195 patients, 165 patients were subjected for aortography, 18 of whom (10.9%), revealed atherosclerotic involvement of the celiac trunk, thereby contraindicating the use of gastroepiploic artery for myocardial revascularization [20].
• In summary, use of the gastroepiploic artery for coronary revascularization provides a reliable arterial conduit without increasing post-operative length of hospitalization, peri-operative morbidity or mortality [21].
• Postoperative coronary angiography in all patients documented a good patency rate (LITA 15/15, RA 21/21, right gastroepiploic artery (RGEA) 2/2, and saphenous vein graft (SVG) 0/2) [22].
• On standard cardiopulmonary bypass and cardioplegic arrest the right and the left mammary arteries (RIMA, LIMA) and the right gastroepiploic artery (RGEA) were anastomosed each to a major coronary branch (none of them as free graft) in each patient [23].

References