Disease relevance of Andrology

• Specifically, the absence of THPK-PCI appears to be a reliable feature of obstructive azoospermia, and this test should be routinely practiced in andrology laboratories [1].
• We have previously observed (M. O. Suescun et al., 1994, Journal of Andrology, 15, 442-448) that rats with autoimmune orchitis (EAO) exhibit increased testosterone production in vitro by isolated testes [2].
• To accomplish this, the authors measured serum levels of INH, I-FSH, B-FSH, LH and testosterone (T) in 98 male patients attending the andrology Centre at Malphighi Hospital (Bologna) for infertility workup [3].

High impact information on Andrology

• The gonadotrophin releasing hormone (GnRH) [luteinising hormone-releasing hormone (LHRH); gonadorelin] agonist buserelin is a promising new agent in the treatment of a variety of disorders in gynaecology and andrology, paediatrics and oncology [4].
• Plasma follicle stimulating hormone, testosterone and urine 5-hydroxyindole acetic acid levels were measured in 300 patients seen at an andrology clinic [5].
• METHODS: Men were invited to attend 178 participating andrology centers for a free of charge visit for counselling about urologic or andrologic conditions [6].
• OBJECTIVE: To evaluate the possible relationships between sperm morphology, acrosome responsiveness to solubilized human zona pellucida, and sperm-zona binding potential among [1] consecutive andrology referrals and [2] randomly selected in vitro fertilization (IVF) cases [7].
• SETTING: Scanian Andrology Centre, Malmö, Sweden; ENEA Casaccia, Rome, Italy; and Department of Occupational Medicine, Aarhus University, Aarhus, Denmark [8].

Biological context of Andrology

• The effects of zinc therapy, low-dose (5-10 mg/day) androgen therapy, and combination therapy of both zinc and low-dose androgen, on sperm motility and seminal zinc concentration were studied in patients referred to the andrology clinic [9].
• Thus, these techniques are recommended for basic research rather than for routine andrology laboratories.Sperm chromatin structure evaluation is applied to detect male factors that may affect the chance of success with IVF as well as natural fertility [10].

Anatomical context of Andrology

• PATIENTS: Semen specimens were selected from the videotape archives of the University of California at Davis Andrology Laboratory and used to produce a videotape reference standard for CASA instrument testing and calibration [11].
• Re: Gonzales, G. F. & Villena, A. (2001) True corrected seminal fructose level: a marker of the function of seminal vesicles in infertile men. International Journal of Andrology 24, 255-60 [12].

Associations of Andrology with chemical compounds

• SETTING: A tertiary care center, the Andrology Clinic, Department of Internal Medicine, University of L'Aquila [13].
• DESIGN: Fresh sperm ejaculates obtained from normal donors to the University of Kentucky Andrology Donor Program were exposed to gossypol [14].
• Two cyclic AMP-independent protein kinase activities have been found associated with buffalo sperm chromatin: a histone kinase highly specific for arginine-rich histone was reported recently (Mudgal et al., 1997: Arch Andrology 38:191-199) and a casein kinase II is described here [15].
• The EAA International Quality Control Programme for Y-Chromosomal microdeletions. European Academy of Andrology [16].
• Re: Letter to the editor: Handelsman DJ and Wu FCW, Asian Joural of Andrology, 2000; (2): 78 [17].

Gene context of Andrology

• SETTING: Andrology laboratories, IVF laboratories, and sperm cryobanks [18].
• SETTING: Andrology laboratory at the Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, Lima, Peru. PATIENT(S): Forty-one male partners of infertile couples attending the andrology laboratory [19].
• Restructuring routinely collected patient data: ORCA applied to andrology [20].
• Low number of Y-chromosome deletions in infertile azoospermic men at a Swedish andrology centre [21].
• Endocrine profiles in pediatric andrology. II. Insulin-dependent diabetic adolescents [22].

Analytical, diagnostic and therapeutic context of Andrology

• This is one of the three bioassays chosen by the College of American Pathologists (CAP) for interlaboratory proficiency testing to assess the standards of in vitro fertilization (IVF) and andrology laboratories [23].

References